Resources Repository
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GuidelinesPublication 2012Dynamic Transmission Modeling: A Report of the ISPOR-SMDM Modeling Task Force-5
This paper reports the consensus-based guidelines on dynamic transmission modeling in health care. The transmissible …
This paper reports the consensus-based guidelines on dynamic transmission modeling in health care. The transmissible nature of communicable diseases is what sets them apart from other diseases modeled by health economists. The probability of a susceptible individual becoming infected at any one point in time (the force of infection) is related to the number of infectious individuals in the population, will change over time, and will feed back into the future force of infection. These…
Mathematical Models | Dynamic Transmission | Dynamic Simulation | Infectious Diseases | Health/Medicine -
GuidelinesPublication 2012Modeling Good Research Practices - Overview: A Report of the ISPOR-SMDM Modeling Task Force-1
This paper provides an overview of the work of the joint Task Force between the …
This paper provides an overview of the work of the joint Task Force between the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) and the Society for Medical Decision Making (SMDM), provides the overarching recommendations, and discusses future work that is needed. The audience for these papers includes anyone who build models, stakeholders who utilize their results, and those concerned with the use of models to support decision making. This article is part 1 of…
Mathematical Models | Dynamic Transmission | Costing Methods | Health Outcomes | Value of Information | State-Transition | Microsimulation | Calibration/Validation | Dynamic Simulation | Decision Analysis | Infectious Diseases | Health/Medicine -
DataPublication 2023Trends in Maternal Mortality 2000 to 2020
This report presents global, regional, and country-level estimates and trends for maternal mortality between 2000 …
This report presents global, regional, and country-level estimates and trends for maternal mortality between 2000 and 2020 produced by the United Nations Maternal Mortality Estimation Inter-Agency Group (MMEIG).* The estimates are intended to inform progress in maternal mortality to support national efforts to meet Sustainable Development Goal (SDG) target 3.1, to reduce maternal mortality to less than 70 maternal deaths per 100,000 live births by 2030. The report is accompanied by a set of country…
Mathematical Models | Health Outcomes | Evidence Synthesis | Maternal/Reproductive Health | Health/Medicine | Global -
ReportPublication 2013Decision and Simulation Modeling Alongside Systematic Reviews
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks …
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The chapter discusses the role of decision analysis and decision-analytic models in health care, specifically within the context of the current emphasis on evidence-based medicine and the proliferation of systematic reviews. It describes the types of model available…
Dynamic Transmission | Evidence Synthesis | State-Transition | Microsimulation | Dynamic Simulation | Health Systems | Clinical Care | Health/Medicine -
GuidelinesPublication 2016Decision Models in Clinical Preventive Services Recommendations
The U.S. Preventive Services Task Force (USPSTF) develops evidence-based recommendations about preventive care based on …
The U.S. Preventive Services Task Force (USPSTF) develops evidence-based recommendations about preventive care based on comprehensive systematic reviews of the best available evidence. Decision models provide a complementary, quantitative approach to support the USPSTF as it deliberates about the evidence and develops recommendations for clinical and policy use. This article describes the rationale for using modeling, an approach to selecting topics for modeling, and how modeling may inform recommendations about clinical preventive services.
Mathematical Models | Health Outcomes | Evidence Synthesis | Decision Analysis | Health Systems | Policy/Regulation | Health/Medicine | North America -
GuidelinesPublication 2016Estimating Health-State Utility for Economic Models: ISPOR Task Force Report
Cost-utility models are increasingly used in many countries to establish whether the cost of a …
Cost-utility models are increasingly used in many countries to establish whether the cost of a new intervention can be justified in terms of health benefits. Health-state utility (HSU) estimates (the preference for a given state of health on a cardinal scale where 0 represents dead and 1 represents full health) are typically among the most important and uncertain data inputs in cost-utility models. Clinical trials represent an important opportunity for the collection of health-utility data.…
Mathematical Models | Preferences/Values | Health Outcomes | Cost-Effectiveness Analysis | Technology Assessment | Health Systems | Health/Medicine | Science/Technology | North America | Europe -
ReportPublication 2016Modeling to Inform Strategies to Improve Population Health
This workshop report summarizes a workshop convened by the Institute of Medicine to explore the potential …
This workshop report summarizes a workshop convened by the Institute of Medicine to explore the potential uses of simulation and other types of modeling for improving health. Participants worked to identify how modeling could inform population health decision making (selecting and refining potential strategies, ranging from interventions to investments) based on lessons learned from models that have been, or have not been, used successfully, opportunities and barriers to incorporating models into decision making, and data needs and…
Mathematical Models | State-Transition | Microsimulation | Dynamic Simulation | Decision Analysis | Chronic Disease/Risk | Environmental Health | Health Systems | Policy/Regulation | Business/Industry | Climate/Environment | Government/Law | Health/Medicine | North America -
GuidelinesPublication 2016Methods for Health Economic Evaluation of Vaccines
This article describes the development of a consensus for health economic evaluations of vaccines to …
This article describes the development of a consensus for health economic evaluations of vaccines to support the development of national guidelines in Europe. While guidelines advocating more standardization of health economic evaluations exist, this article aims to address several immunization-specific aspects (e.g. indirect effects or discounting approach) which are still a subject of debate. The systematic literature review search was informed by expert opinion. 2,838 articles were returned from the search and 26 were finally…
Dynamic Transmission | Costing Methods | Cost-Effectiveness Analysis | Infectious Diseases | Health Systems | Health/Medicine | Europe -
ReportPublication 2015Chapter 4: Cervical Cancer
This chapter focuses on the possibility of primary prevention of cervical cancer as a result …
This chapter focuses on the possibility of primary prevention of cervical cancer as a result of the introduction of two commercially available vaccines against human papillomavirus (HPV). Few low- and middle-income countries (LMICs) have initiated or sustained cytology-based cervical cancer prevention programs, and these countries experience very high incidence and mortality rates. Fortunately, alternative strategies to prevent cervical cancer have been investigated and extensively evaluated in these settings. The authors report findings from cost-effectiveness analyses…
Mathematical Models | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Clinical Care | Health/Medicine | Science/Technology | Global