Resources Repository
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BookPublication 2003WHO Guide to Cost-Effectiveness Analysis
This 2003 guide provides a method of assessing the cost-effectiveness of health interventions for an …
This 2003 guide provides a method of assessing the cost-effectiveness of health interventions for an international audience. The authors aim to inform the policy maker and to maximize the generalizability of results across settings. Part I begins with a description of cost-effectiveness analysis. It then considers issues relating to study design, estimating costs, assessing health effects, discounting, uncertainty and sensitivity analysis, and reporting results. Part II provides examples to illustrate the principles in Part I. Detailed discussions…
Priority Setting/Ethics | Mathematical Models | Health Outcomes | Global | Costing Methods | Evidence Synthesis | Cost-Effectiveness Analysis | Health Systems | Health/Medicine -
ReviewPublication 2001Modeling for Health Care and Other Policy Decisions: Uses, Roles and Validity
This is a review article of the role of modeling approaches to guide decision making …
This is a review article of the role of modeling approaches to guide decision making in health care and other domains. The role of models to support recommendations on the cost-effective use of medical technologies and pharmaceuticals is controversial. At the heart of the controversy is the degree to which experimental or other empirical evidence should be required prior to model use. The authors argue that the controversy stems in part from a misconception that…
Priority Setting/Ethics | Mathematical Models | Technology Assessment | North America | Evidence Synthesis | Environmental Health | Health Systems | Policy/Regulation | Business/Industry | Climate/Environment | Economics/Finance | Energy/Engineering | Government/Law | Health/Medicine -
BookPublication 1996Cost-Effectiveness in Health and Medicine, 1st Edition
In 1993, the US Public Health Service convened a panel of 13 nongovernment scientists and …
In 1993, the US Public Health Service convened a panel of 13 nongovernment scientists and scholars with expertise in economics, clinical medicine, ethics, and statistics to review the state of cost-effectiveness analysis and to develop recommendations for its conduct and use in health and medicine. Publishing their results in 1996, they proposed the most explicit set of guidelines (together with their rationale) ever defined on the conduct of CEAs. The panel recommended analysts include a "reference-case"…
Priority Setting/Ethics | Preferences/Values | Health Outcomes | North America | Costing Methods | Evidence Synthesis | Value of Information | Cost-Effectiveness Analysis | Health Systems | Policy/Regulation | Economics/Finance | Health/Medicine -
Working PaperPublication 2024Economic Evaluation Primer
Economic evaluation is a powerful tool, encouraging the systematic collection and assessment of the evidence …
Economic evaluation is a powerful tool, encouraging the systematic collection and assessment of the evidence needed to support sound policy decisions. In low- and middle-income countries, where resources are especially scarce and needs are very great, such decisions are exceptionally difficult. In these settings, economic evaluation can be particularly useful in determining how to best improve health and welfare. Typically, cost-effectiveness analysis (CEA) is used to prioritize interventions within the health care sector. This approach…
Priority Setting/Ethics | Health Outcomes | Global | Costing Methods | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Policy/Regulation -
ReviewPublication 2023Adaptive Health Technology Assessment: A Scoping Review of Methods
This study explores adaptive health technology assessment (aHTA) as an expedited alternative to full HTA, …
This study explores adaptive health technology assessment (aHTA) as an expedited alternative to full HTA, aiming to support universal health coverage by leveraging HTA evidence from other settings. The scoping review identified and mapped existing aHTA methods, examining their triggers, strengths, and weaknesses. Methods included searching HTA agencies' and networks' websites, and published literature, with findings narratively synthesized. The review found aHTA methods in 20 countries and one HTA network across the Americas, Europe, Africa,…
Priority Setting/Ethics | Technology Assessment | Global | Cost-Effectiveness Analysis | Health/Medicine -
ArticlePublication 2023Catalogues of EQ-5D-3L Health-Related Quality of Life Scores for 199 Chronic Conditions and Health Risks for Use in the UK & the U.S.
This study aimed to create UK and US EQ-5D-3L-based health-related quality of life (HRQoL) utility …
This study aimed to create UK and US EQ-5D-3L-based health-related quality of life (HRQoL) utility population catalogues for 199 chronic conditions using ICD-10 codes and health risks. It also sought to develop regression models to predict these utilities in other populations. Methods involved applying UK and US EQ-5D-3L value sets to responses from a Danish dataset, which combined national health survey data with national registers containing patient information on diagnoses, healthcare activities, and socio-demographics. Adjusted…
Preferences/Values | Health Outcomes | North America | Health/Medicine | Europe -
ArticlePublication 2023Simulation-Based Estimates and Projections of Global, Regional and Country-Level Maternal Mortality by Cause, 1990-2050
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given …
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given the many causes and frequent underreporting of maternal deaths. The authors developed a structural microsimulation model of Global Maternal Health (GMatH) for 200 countries and territories using demographic, epidemiologic, clinical and health system data synthesized from the medical literature, Civil Registration Vital Statistics systems and Demographic and Health Survey data. The model was calibrated to empirical data from 1990 to…
Calibration/Validation | Health Outcomes | Global | Evidence Synthesis | Microsimulation | Maternal/Reproductive Health | Health Systems | Clinical Care | Health/Medicine -
DataPublication 2023Trends in Maternal Mortality 2000 to 2020
This report presents global, regional, and country-level estimates and trends for maternal mortality between 2000 …
This report presents global, regional, and country-level estimates and trends for maternal mortality between 2000 and 2020 produced by the United Nations Maternal Mortality Estimation Inter-Agency Group (MMEIG).* The estimates are intended to inform progress in maternal mortality to support national efforts to meet Sustainable Development Goal (SDG) target 3.1, to reduce maternal mortality to less than 70 maternal deaths per 100,000 live births by 2030. The report is accompanied by a set of country…
Mathematical Models | Health Outcomes | Global | Evidence Synthesis | Maternal/Reproductive Health | Health/Medicine -
ArticlePublication 2023Achieving the Cancer Moonshot Goal
The Cancer Moonshot seeks to reduce age-standardized cancer mortality rates by at least 50% over …
The Cancer Moonshot seeks to reduce age-standardized cancer mortality rates by at least 50% over the next 25 years. This article estimates trends in U.S. cancer mortality for all cancers and the six leading types and reviews opportunities to prevent, detect, and treat these common cancers.
Priority Setting/Ethics | Mathematical Models | North America | Health Systems | Clinical Care | Health/Medicine