This 2003 guide provides a method of assessing the cost-effectiveness of health interventions for an international audience. The authors aim to inform the policy maker and to maximize the generalizability of results across settings. Part I begins with a description of cost-effectiveness analysis. It then considers issues relating to study design, estimating costs, assessing health effects, discounting, uncertainty and sensitivity analysis, and reporting results. Part II provides examples to illustrate the principles in Part I. Detailed discussions of selected technical issues and applications are provided in a series of background papers, originally published in journals. The final chapter is devoted to ethical considerations.
Tan-Torres Edejer T, Baltussen R, Adam T et al, eds. Making Choices in Health: WHO Guide to Cost-Effectiveness Analysis. World Health Organization 2003. http://www.who.int/choice/book/en