Resources Repository
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ReviewPublication 2022Significance of Advanced COVID-19 Diagnostic Testing in Pandemic Control Measures
Over the past two years of the COVID-19 pandemic, the scientific community has mounted significant …
Over the past two years of the COVID-19 pandemic, the scientific community has mounted significant efforts to combat the highly transmissible SARS-CoV-2 virus. Despite substantial progress in vaccines and treatments, leading to lower hospitalization and death rates, the virus has continued to evolve, primarily through mutations. From the onset, diagnostic tests have been crucial in identifying and controlling the virus spread. The scientific world has pioneered various diagnostic techniques, including nucleic acid, antigen, and antibody-based…
Test Performance | Health Systems | Infectious Diseases | Clinical Care | Health/Medicine | Science/Technology | North America -
ReviewPublication 2022Diagnostics for COVID-19: Moving from Pandemic Response to Control
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 …
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 infections. Each test type remains vital as we shift from responding to controlling the pandemic. Molecular tests, like PCR, are highly precise in identifying viral RNA and are endorsed by the WHO for confirming cases and guiding public health actions. Antigen rapid tests spot viral proteins and, while less accurate than molecular tests, are quicker, more affordable, simpler, and can…
Test Performance | Health Systems | Infectious Diseases | Clinical Care | Health/Medicine | Science/Technology -
EditorialPublication 2020Waiting for Certainty on COVID-19 Antibody Tests — At What Cost?
This perspective anticipates the availability of serologic antibody testing and considers its potential usefulness in mitigation …
This perspective anticipates the availability of serologic antibody testing and considers its potential usefulness in mitigation policy to reduce COVID-19 transmission. For example: Could we screen for serologic antibodies as a proxy for possible immunity and identify people who could return to the workplace with less severe mitigation measures? The authors acknowledge the uncertainties raised by many policy actors, including the WHO, such as, "Do antibodies confer immunity and, if so, for how long? How accurate is…
Test Performance | Government/Law | Health Systems | Probability/Bayes | Technology Assessment | Infectious Diseases | Policy/Regulation | Health/Medicine | Global | North America -
ArticlePublication 2020Translating Population Evidence to Individual Patients
In this paper, the authors describe the differences in population level outcomes compared to individual …
In this paper, the authors describe the differences in population level outcomes compared to individual patients and discuss ways that these are differences. The authors cover topics including the difference between relative and absolute risk and benefit. They use an example of the decision to start anticoagulation in new-onset atrial fibrillation to discuss translating population level evidence to treatment of an individual. These options include generalizability, subgroup analysis, prediction rules, following response to therapy, and even…
Test Performance | Health Systems | Evidence Synthesis | Clinical Care | Health/Medicine -
ArticlePublication 2019Measuring Progress Towards Universal Health Coverage
This article, published in BMJ Global Health, aims to estimate the 2015 national and subnational …
This article, published in BMJ Global Health, aims to estimate the 2015 national and subnational universal health coverage (UHC) service coverage status for Ethiopia. The UHC service coverage index is constructed from the geometric means of component indicators: first, within each of four major categories and then across all components to obtain the final summary index. The authors estimate UHC service coverage at the subnational level using a variety of surveys and routinely collected administrative…
Test Performance | Health Systems | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2017Cost-Effectiveness of Testing and Treatment for Latent TB
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve …
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve TB elimination in the United States. This analysis estimated health outcomes, costs, and cost-effectiveness of LTBI testing and treatment among non-US born residents with and without medical comorbidities (e.g., diabetes, HIV infection, and end-stage renal disease). A decision analytic tree and Markov cohort simulation model was used to compare the following strategies: no testing, tuberculin skin test (TST), interferon gamma release assay…
Test Performance | Health Systems | State-Transition | Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Global | North America -
Resource PortalWeb Portal, Teaching Resource 2024Cochrane
Cochrane produces reviews which study all of the best available evidence generated through research and …
Cochrane produces reviews which study all of the best available evidence generated through research and make it easier to inform decisions about health. In addition to the production and dissemination of systematic reviews, housed in the Cochrane Library, they provide a host of resources such as handbooks and guidelines, interactive learning modules, web casts and other educational public goods. Cochrane is a not-for profit organisation with collaborators from more than 120 countries working together to produce…
Test Performance | Health Systems | Evidence Synthesis | Technology Assessment | Health/Medicine | Global -
Teaching PackWeb Portal, Teaching Resource 2018Teaching Pack: Teaching Prototypes for Decision Analysis
These videos, developed by Professor Myriam Hunink during an immersion residency at the Center for …
These videos, developed by Professor Myriam Hunink during an immersion residency at the Center for Health Decision Science (CHDS) Media Hub, reflect experiments to augment brick and mortar teaching with multimedia materials that emphasize visualization of basic concepts. The first video introduces decision making under uncertainty, and illustrates the use of probability and odds to quantitatively express uncertainty. The second and third videos introduce probability revision visually and analytically, showing how an initial probability is…
Test Performance | Health Systems | Probability/Bayes | Value of Information | Chronic Disease/Risk | Health/Medicine | North America | Europe | High School | College | Graduate | Doctoral | Critical Thinking/Analysis | Graphics/Visualization | Quantitative Literacy -
DataWeb Portal 2024Healthcare Cost and Utilization Project (HCUP)
The Healthcare Cost and Utilization Project (HCUP) is the most comprehensive source of hospital data in …
The Healthcare Cost and Utilization Project (HCUP) is the most comprehensive source of hospital data in the United States, including information on in-patient care, ambulatory care, and emergency department visits. HCUP enables researchers, insurers, policymakers and others to study health care delivery and patient outcomes over time, and at the national, regional, State, and community levels. The Agency for Healthcare Research and Quality (AHRQ) provides a range of data resources in the form of online, searchable…
Test Performance | Government/Law | Health Systems | Costing Methods | Health Outcomes | Evidence Synthesis | Cost-Effectiveness Analysis | Technology Assessment | Infectious Diseases | Maternal/Reproductive Health | Child/Nutrition | Chronic Disease/Risk | Mental Health | Injuries/Accidents | Social Determinants | Policy/Regulation | Economics/Finance | Health/Medicine | Science/Technology | North America