Diagnostics for COVID-19: Moving from Pandemic Response to Control
2022
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 infections. Each test type remains vital as we shift from responding to controlling the pandemic. Molecular tests, like PCR, are highly precise in identifying viral RNA and are endorsed by the WHO for confirming cases and guiding public health actions. Antigen rapid tests spot viral proteins and, while less accurate than molecular tests, are quicker, more affordable, simpler, and can identify those most infectious. These tests support public health by screening high-risk individuals, ensuring safe travel, reopening schools and social activities, and aiding economic rebound. As vaccines become more widespread, antibody tests monitor the response to infection or vaccination. They are valuable for public health insights but aren't suitable for confirming immunity due to uncertain protection correlates.
Diagnostics for COVID-19: Moving from Pandemic Response to Control
Source:
Peeling RW, Heymann DL, Teo YY et al. Diagnostics for COVID-19: Moving from Pandemic Response to Control. The Lancet 2022; 399 (10326): 757-768. https://doi.org/10.1016/s0140-6736(21)02346-1