Resources Repository
-
ArticlePublication 2023Simulation-Based Comparative Effectiveness Analysis of Policies to Improve Global Maternal Health Outcomes
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) …
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) to less than 70 maternal deaths per 100,000 live births by 2030, with no individual country exceeding 140. However, on current trends the goals are unlikely to be met. The authors used an empirically calibrated Global Maternal Health microsimulation model, which simulates individual women in 200 countries and territories to evaluate the impact of different interventions and strategies from 2022…
Microsimulation | Health Outcomes | Global | Maternal/Reproductive Health | Mathematical Models | Calibration/Validation | Health Systems | Clinical Care | Health/Medicine -
ArticlePublication 2023Simulation-Based Estimates and Projections of Global, Regional and Country-Level Maternal Mortality by Cause, 1990-2050
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given …
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given the many causes and frequent underreporting of maternal deaths. The authors developed a structural microsimulation model of Global Maternal Health (GMatH) for 200 countries and territories using demographic, epidemiologic, clinical and health system data synthesized from the medical literature, Civil Registration Vital Statistics systems and Demographic and Health Survey data. The model was calibrated to empirical data from 1990 to…
Microsimulation | Health Outcomes | Global | Maternal/Reproductive Health | Evidence Synthesis | Calibration/Validation | Health Systems | Clinical Care | Health/Medicine -
DataPublication 2023Trends in Maternal Mortality 2000 to 2020
This report presents global, regional, and country-level estimates and trends for maternal mortality between 2000 …
This report presents global, regional, and country-level estimates and trends for maternal mortality between 2000 and 2020 produced by the United Nations Maternal Mortality Estimation Inter-Agency Group (MMEIG).* The estimates are intended to inform progress in maternal mortality to support national efforts to meet Sustainable Development Goal (SDG) target 3.1, to reduce maternal mortality to less than 70 maternal deaths per 100,000 live births by 2030. The report is accompanied by a set of country…
Health Outcomes | Global | Maternal/Reproductive Health | Evidence Synthesis | Mathematical Models | Health/Medicine -
ArticlePublication 2010Alternative Strategies to Reduce Maternal Mortality in India: A Cost-Effectiveness Analysis
This article, published in PLoS Medicine, conducted a cost-effectiveness analysis of strategies to improve pregnancy …
This article, published in PLoS Medicine, conducted a cost-effectiveness analysis of strategies to improve pregnancy and childbirth safety in India. Country- and region-specific data were synthesized using a computer-based model that simulates the natural history of pregnancy and pregnancy-associated complications in individual women, and considers delivery location, attendant, and facility level. Model validation compared projected maternal indicators with empiric data. Strategies consisted of improving coverage of effective interventions that could be provided individually or packaged…
Microsimulation | Global | Maternal/Reproductive Health | Evidence Synthesis | Mathematical Models | Cost-Effectiveness Analysis | Economics/Finance | Health/Medicine | Asia & Pacific -
ArticlePublication 2023Single-Arm Trial Design Estimates Efficacy
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and …
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and of vaccination modifications are needed, but randomized controlled trials are costly and face logistical and ethical challenges. In this study, the authors demonstrate proof-of-principle that a single-arm design yields valid estimates with similar precision to a randomized controlled trial.
Health Outcomes | Global | Maternal/Reproductive Health | Infectious Diseases | Policy/Regulation | Health/Medicine -
ArticlePublication 2022WHO ACTION-I Trial in Low Resource Countries
This study evaluated the cost-effectiveness of dexamethasone administration in dexamethasone in pregnant women at risk …
This study evaluated the cost-effectiveness of dexamethasone administration in dexamethasone in pregnant women at risk of early preterm birth using data from a multicentre, randomized, placebo-controlled trial in Bangladesh, India, Kenya, Nigeria, and Pakistan. Primary cost data were collected in 28 hospitals across the 5 countries. A decision tree model was used to compare dexamethasone treatment to no intervention from a health-care sector perspective. Administration of dexamethasone averted 38 neonatal deaths per 1000 woman–baby units…
Health Outcomes | Global | Maternal/Reproductive Health | Mathematical Models | Cost-Effectiveness Analysis | Child/Nutrition | Clinical Care | Sub-Saharan Africa | Asia & Pacific -
DataInteractive 2017Monitoring Health for the SDGs: Data Visualization Dashboard
This web portal from the World Health Organization (WHO) accompanies the 2017 report, World Health …
This web portal from the World Health Organization (WHO) accompanies the 2017 report, World Health Statistics: Monitoring Health for the SDGs. Powered by data in the WHO’s Global Health Observatory (GHO), the portal presents visualizations on 22 health and health-related targets of the Sustainable Development Goals from all member countries, covering a number of topics including poverty, health and well-being, malnutrition, sanitation, clean energy, sustainable urban development, and more.Published every year since 2005, World Health…
Health Outcomes | Global | Environmental Health | Child/Nutrition | Chronic Disease/Risk | Social Determinants | Global Governance | Climate/Environment | Education/Labor | Government/Law | Health/Medicine -
DataWeb Portal 2024CEA Registry
The CEA Registry is a comprehensive database containing detailed information on more than 14,500 standardized …
The CEA Registry is a comprehensive database containing detailed information on more than 14,500 standardized cost-effectiveness ratios and more than 21,900 utility weights published in over 5,600 peer-reviewed cost-utility analyses. It details studies published from 1976 through 2016 and is regularly updated. These studies estimate health benefits, in terms of quality-adjusted life-years (QALYs), and incremental costs for a wide range of health and medical interventions. Open access is provided for basic search functions against the…
Health Outcomes | Global | Maternal/Reproductive Health | Cost-Effectiveness Analysis | Technology Assessment | Infectious Diseases | Child/Nutrition | Chronic Disease/Risk | Mental Health | Injuries/Accidents | Health Systems | Health/Medicine -
ArticlePublication 2016Costs and Benefits of Integrated RMNCH
This chapter assesses the costs and benefits of delivering a set of integrated reproductive, maternal, …
This chapter assesses the costs and benefits of delivering a set of integrated reproductive, maternal, newborn and child health interventions in countries with high child and maternal mortality to demonstrate that very high returns can be achieved through this investment and to underscore the importance of an accurate assessment of those returns. This includes the full range of costs involved in delivering integrated care and the full range of benefits that flow from the interventions.…
Priority Setting/Ethics | Global | Maternal/Reproductive Health | Costing Methods | Child/Nutrition | Health Systems | Economics/Finance | Health/Medicine