Resources Repository
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BookPublication 1980Clinical Decision Analysis
This text was conceived and developed in the Harvard T.H. Chan School of Public Health …
This text was conceived and developed in the Harvard T.H. Chan School of Public Health at the Center for the Analysis of Health Practices. The book had its origins in a set of classroom materials developed during the academic year 1974-75 for an elective course in medical decision making at the Harvard Medical School. In this book students are shown how to structure clinical decision problems, how to systematically formulate the intertwining roles of diagnosis and treatment, how to…
Decision Analysis | State-Transition | Health Outcomes | Health/Medicine | Global | Probability/Bayes | Preferences/Values | Costing Methods | Test Performance | Value of Information | Cost-Effectiveness Analysis | Infectious Diseases | Child/Nutrition | Chronic Disease/Risk | Economics/Finance | North America | Europe | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ArticlePublication 2023Simulation-Based Comparative Effectiveness Analysis of Policies to Improve Global Maternal Health Outcomes
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) …
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) to less than 70 maternal deaths per 100,000 live births by 2030, with no individual country exceeding 140. However, on current trends the goals are unlikely to be met. The authors used an empirically calibrated Global Maternal Health microsimulation model, which simulates individual women in 200 countries and territories to evaluate the impact of different interventions and strategies from 2022…
Microsimulation | Health Outcomes | Health/Medicine | Global | Mathematical Models | Calibration/Validation | Maternal/Reproductive Health | Health Systems | Clinical Care -
ArticlePublication 2023Simulation-Based Estimates and Projections of Global, Regional and Country-Level Maternal Mortality by Cause, 1990-2050
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given …
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given the many causes and frequent underreporting of maternal deaths. The authors developed a structural microsimulation model of Global Maternal Health (GMatH) for 200 countries and territories using demographic, epidemiologic, clinical and health system data synthesized from the medical literature, Civil Registration Vital Statistics systems and Demographic and Health Survey data. The model was calibrated to empirical data from 1990 to…
Microsimulation | Health Outcomes | Health/Medicine | Global | Evidence Synthesis | Calibration/Validation | Maternal/Reproductive Health | Health Systems | Clinical Care -
ReviewPublication 2023Handbook of Vaccine Health Economics
The open-access book, "Handbook of Applied Health Economics in Vaccines," looks at the complexities of …
The open-access book, "Handbook of Applied Health Economics in Vaccines," looks at the complexities of vaccine discovery, financing, and distribution. It highlights the inadequacy of standard economic models for vaccines. The book explores alternative principles challenging market-based approaches and equips readers with tools for assessing costs and benefits through practical exercises. It serves as a comprehensive resource for decision-making in vaccine development and distribution and emphasizes the importance of considering broader perspectives beyond economic efficiency.…
Decision Analysis | Health Outcomes | Health/Medicine | Global | Costing Methods | Evidence Synthesis | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Policy/Regulation | Graduate | Doctoral | Professional -
Working PaperPublication 2018Valuing Nonfatal Health Risk Reductions
This paper explores approaches for valuing nonfatal risk reductions associated with policy choices in low- …
This paper explores approaches for valuing nonfatal risk reductions associated with policy choices in low- and middle-income countries. The approach for valuation ideally would be based on estimates of individuals’ willingness to pay for changes in their own risks. However, high quality valuation research is not available for many nonfatal conditions even in high-income settings. Typically, two approaches are used either alone or in combination as rough proxies. The first involves applying an estimate of…
Decision Analysis | Health Outcomes | Health/Medicine | Global | Preferences/Values | Priority Setting/Ethics | Benefit-Cost Analysis | Social Determinants | Policy/Regulation | Economics/Finance | Critical Thinking/Analysis -
Resource PackWeb Portal, Teaching Resource 2018Resource Pack: Cervical Cancer Models
This resource pack, curated by the Center for Health Decision Science, is a collection of …
This resource pack, curated by the Center for Health Decision Science, is a collection of models of HPV-related cervical cancer, differing in design, structure and features based on analytic objectives. In many ways, HPV and its related diseases represent a prototypical public health problem given the communicable and non-communicable nature of disease, opportunities for intervention along the entire disease spectrum (e.g., primary and secondary prevention, diagnosis, treatment), the varied ages at which interventions are targeted…
Microsimulation | State-Transition | Health/Medicine | Global | Mathematical Models | Dynamic Transmission | Calibration/Validation | Dynamic Simulation | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Clinical Care | Business/Industry | Economics/Finance | Science/Technology -
ArticlePublication 2017Cost-Effectiveness of Testing and Treatment for Latent TB
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve …
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve TB elimination in the United States. This analysis estimated health outcomes, costs, and cost-effectiveness of LTBI testing and treatment among non-US born residents with and without medical comorbidities (e.g., diabetes, HIV infection, and end-stage renal disease). A decision analytic tree and Markov cohort simulation model was used to compare the following strategies: no testing, tuberculin skin test (TST), interferon gamma release assay…
Microsimulation | State-Transition | Health/Medicine | Global | Test Performance | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Economics/Finance | North America -
Resource PortalWeb Portal, Teaching Resource 2024Decision Sciences Institute
The Decision Sciences Institute (DSI) was founded in 1968 as the American Institute for the …
The Decision Sciences Institute (DSI) was founded in 1968 as the American Institute for the Decision Sciences (renamed to the Decision Science Institute in 1986). DSI is an independent non-profit organization with a mission to enrich the discipline of decision sciences and improve educational programs and instruction in decision sciences. DSI conducts annual meetings at the national and the regional levels, and produces a monthly news publication called “Decision Line” as well as two journals,…
Operations Research | Decision Analysis | Health/Medicine | Global | Business/Industry | Climate/Environment | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Quantitative Literacy -
OrganizationWeb Portal 2024Operational Research Society
The Operational Research Society (ORS) was founded over 60 years ago as a successor to …
The Operational Research Society (ORS) was founded over 60 years ago as a successor to the Operations Research Club that had been set up in 1948. The UK’s OR Society is the oldest-established learned society catering to the Operational Research (O.R.) profession, and one of the largest in the world, with 2,700 members from 66 countries. Core activities of ORS include publishing journals to disseminate the latest developments in O.R., and organizing national, international and specialist conferences. The Journal…
Operations Research | Decision Analysis | Health/Medicine | Global | Government/Law | Military/Defense