Resources Repository
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Tutorial/PrimerPublication, Teaching Resource 2015White Paper: Retrospective Benefit-Cost Analysis
In this article the authors consider how benefit-cost analysis can be used retrospectively to promote …
In this article the authors consider how benefit-cost analysis can be used retrospectively to promote understanding of the impacts after a policy is implemented. Serving as a brief primer, the authors propose that analysis can be useful for identifying needed reforms as well as in improving the conduct of future prospective analyses. The major challenges relate to estimating what would have occurred in the absence of the policy and separating the effects of the policy…
Economics/Finance | Priority Setting/Ethics | Benefit-Cost Analysis | Social Determinants | Environmental Health | Policy/Regulation | Culture/Society | Government/Law | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Policy Translation -
Tutorial/PrimerPublication, Teaching Resource 2015Educational Review of the Statistical Issues in Utility Data for CEA
The aim of cost-utility analysis is to support decision making in healthcare by providing a …
The aim of cost-utility analysis is to support decision making in healthcare by providing a standardized mechanism for comparing resource use and health outcomes across programmes of work. The focus of this review is the denominator of the cost-utility analysis, specifically the methodology and statistical challenges associated with calculating QALYs from patient-level data collected as part of a trial. The authors provide a brief description of the most common questionnaire used to calculate patient level…
Health/Medicine | Preferences/Values | Health Outcomes | Cost-Effectiveness Analysis -
ReportPublication 2015Improving Diagnosis in Health Care
Getting the right diagnosis is a key aspect of health care - it provides an …
Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. This report, Improving Diagnosis in Health Care, explains that diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients.…
Health/Medicine | Probability/Bayes | Health Outcomes | Test Performance | Value of Information | Health Systems | North America -
ReportPublication 2015Modeling to Improve Policy Decisions in the Americas: Noncommunicable Diseases
In the Region of the Americas, noncommunicable diseases (NCDs) are a clear threat not only …
In the Region of the Americas, noncommunicable diseases (NCDs) are a clear threat not only to human health, but also to a country’s economic development and growth. The evidence on both of these counts is compelling. In 2012, cardiovascular disease, diabetes, cancers, chronic respiratory conditions including asthma, and other NCDs were the cause of 4.5 million deaths in the Americas. Of that total number, 1.5 million of them were premature, occurring among people aged 30-69…
Health/Medicine | Priority Setting/Ethics | Costing Methods | Mathematical Models | State-Transition | Microsimulation | Decision Analysis | Cost-Effectiveness Analysis | Chronic Disease/Risk | Mental Health | Latin America & Caribbean -
ReportPublication 2015Opioid Dependence: Final Report
This report from the Institute for Clinical and Economic Review (ICER) examines the comparative effectiveness and value …
This report from the Institute for Clinical and Economic Review (ICER) examines the comparative effectiveness and value of interventions for the management of opioid dependence. The goals of the report are to document the federal and New England state regulations affecting treatment options, provide an overview of existing clinical guidelines and payer coverage policies, and summarize the evidence on the different management approaches for opioid dependence, including special considerations for adolescents. An appendix is provided by ICER.…
Health/Medicine | Preferences/Values | Health Outcomes | Evidence Synthesis | Cost-Effectiveness Analysis | Technology Assessment | Chronic Disease/Risk | Mental Health | Health Systems | Policy/Regulation | Business/Industry | Government/Law | Science/Technology | North America -
ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Calibration/Validation | Health/Medicine | Health Outcomes | Mathematical Models | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Global | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
Lesson/ModulePublication, Teaching Resource 2014Scientific Decision-Making: Teacher's Guide
This guide provides high-school level activities and readings on how decision-making can affect our health, …
This guide provides high-school level activities and readings on how decision-making can affect our health, focusing on cardiovascular health. Exercises include: Decisions and Risks Smarter Choices Introduction to Personal Stories Heart: Basic Measurements Calculating Coronary Artery Disease Risk Team Diagnosis of Three Cases Comparative Effectiveness Decision-Making Tools These exercises explore the biology of the heart, a coronary disease model, risk factors for heart disease, and a wider range of activities around health decision-making.
Health/Medicine | Decision Theory | Decision Analysis | Chronic Disease/Risk | Social Determinants | High School | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
GuidelinesPublication 2014Methods for Economic Evaluation Project
This report details the work of the Methods for Economic Evaluation Project (MEEP), which aims …
This report details the work of the Methods for Economic Evaluation Project (MEEP), which aims to promote a consistency in the methods used for economic evaluations. The report is targeted especially at low and middle-income countries (LMICs). The Bill and Melinda Gates Foundation is a major funder of health economic evaluations in LMICs, but there is substantial variation in the methods used and the quality of the analyses produced. The report drew on expertise from…
Health/Medicine | Priority Setting/Ethics | Costing Methods | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Climate/Environment | Education/Labor | Global -
ArticlePublication 2013Validation and Calibration of a Simulation Model of Pediatric HIV Infection
The authors developed a microsimulation model of pediatric HIV disease progression using the Cost-Effectiveness of …
The authors developed a microsimulation model of pediatric HIV disease progression using the Cost-Effectiveness of Preventing AIDS Complications (CEPAC) model framework. This CEPAC-Pediatric model was then validated by varying CD4 data and comparing the corresponding model-generated survival curves to empirical survival curves obtained from the International Epidemiologic Database to Evaluate AIDS (IeDEA). The model was calibrated to other African countries by systematically varying immunologic and HIV mortality-related input parameters. In the calibration analyses, the model-generated…
Calibration/Validation | Health/Medicine | Microsimulation | Infectious Diseases | Child/Nutrition | Sub-Saharan Africa