Resources Repository
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ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Chronic Disease/Risk | Health Outcomes | Mathematical Models | Calibration/Validation | Cost-Effectiveness Analysis | Infectious Diseases | Health Systems | Health/Medicine | Global | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
Lesson/ModuleWeb Portal, Teaching Resource 2014Maths and Our Health
This learning module provides teaching packs to explore biomedical real-world applications of probability and statistics …
This learning module provides teaching packs to explore biomedical real-world applications of probability and statistics in decision-making. Each pack provides videos and supplemental materials, including presentations, worksheets, and games. Topics include: “Eating Bacon Sandwiches is Bad for You!” Evaluating Risk Epidemics: Modelling with Mathematics Life Saving Maths: How Does Vaccination Work? The Economics of Health: How Do We Decide? The Test is Positive: But What Are the Odds It’s Wrong?
Chronic Disease/Risk | Test Performance | Decision Theory | Mathematical Models | Decision Analysis | Infectious Diseases | Child/Nutrition | Economics/Finance | Health/Medicine | Science/Technology | Global | Middle School | High School | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ArticlePublication 2014Cost of a Primary Care-Based Childhood Obesity Prevention Intervention
This study evaluated the cost of a primary care-based obesity prevention intervention (High Five for …
This study evaluated the cost of a primary care-based obesity prevention intervention (High Five for Kids) for children ages 2-6 years, compared to usual care. U.S. pediatric guidelines recommend that childhood obesity counseling be done in primary care settings. The clinical trial aimed to modify children’s nutrition and TV viewing habits through a motivational interviewing intervention. The authors assessed the visit-related costs for children enrolled in the trial, and found that the mean costs for…
Chronic Disease/Risk | Costing Methods | Decision Analysis | Child/Nutrition | Clinical Care | Economics/Finance | Health/Medicine | North America -
GuidelinesPublication 2013Decision and Simulation Modeling in Systematic Reviews
The purpose of this review is to provide guidance for determining when incorporating a decision-analytic …
The purpose of this review is to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The purpose of systematic reviews is to synthesize the current scientific literature on a particular topic in the form of evidence reports and technology assessments to assist public and private organizations in developing strategies that improve the quality of health care and decision making. However, there…
Chronic Disease/Risk | Evidence Synthesis | Mathematical Models | Decision Analysis | Infectious Diseases | Child/Nutrition | Health/Medicine | North America -
ArticlePublication 2011Model-Based Analyses to Compare Health and Economic Outcomes of Cancer Control: Inclusion of Disparities
In order to identify strategies that improve both population health and ensure its equitable distribution, …
In order to identify strategies that improve both population health and ensure its equitable distribution, the authors developed a typology of cancer disparities that considers types of inequalities among black, white, and Hispanic populations across different cancers. This paper reports on the typology using an existing disease simulation model of cervical cancer that was calibrated to clinical, epidemiological, and cost data in the United States and presents characteristics important for policy discussions. The typology proposed…
Chronic Disease/Risk | State-Transition | Priority Setting/Ethics | Cost-Effectiveness Analysis | Social Determinants | Health Systems | Clinical Care | Culture/Society | Health/Medicine | Science/Technology | North America -
ReviewPublication 2011Simulation Models of Obesity: A Review of the Literature
Simulation models combine information from a variety of sources to provide a useful tool for …
Simulation models combine information from a variety of sources to provide a useful tool for examining how the effects of obesity unfold over time and impact population health. They can aid in the understanding of the complex interaction of the drivers of diet and activity and their relation to health outcomes. This paper provided an overview of different types of simulation models used to evaluate the potential impact of policies to address the obesity epidemic.…
Chronic Disease/Risk | State-Transition | Mathematical Models | Microsimulation | Calibration/Validation | Decision Analysis | Cost-Effectiveness Analysis | Child/Nutrition | Economics/Finance | Food/Agriculture | Health/Medicine -
ReviewPublication 2008Modeling Cervical Cancer Prevention in Developed Countries
Decision-analytic models are increasingly developed to simulate disease burden and interventions in different settings in …
Decision-analytic models are increasingly developed to simulate disease burden and interventions in different settings in order to evaluate the benefits and cost-effectiveness of primary and secondary interventions. This article is a review of mathematical models that have been used to evaluate HPV vaccination in the context of developed countries with existing screening programs. Despite variations in model assumptions and uncertainty in existing data, pre-adolescent vaccination of females in the setting of current screening practices has…
Chronic Disease/Risk | State-Transition | Mathematical Models | Dynamic Transmission | Microsimulation | Calibration/Validation | Infectious Diseases | Health/Medicine | Science/Technology -
ArticlePublication 2002Empirically Calibrated Model of Hepatitis C Virus Infection in the United States
This article presents an epidemiologic model of hepatitis C in the United States. The authors …
This article presents an epidemiologic model of hepatitis C in the United States. The authors used empirical calibration of model parameters to gain insights into uncertainty in the natural history of hepatitis C and to improve future projections. The authors identified model inputs by way of a systematic review. Model simulations were conducted and model predictions were compared with epidemiologic data on infection prevalence and mortality from liver cancer. Goodness-of-fit criteria were used to identify…
Chronic Disease/Risk | State-Transition | Mathematical Models | Calibration/Validation | Infectious Diseases | Health/Medicine | North America