Resources Repository
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ArticlePublication 2020Impact of Treatment and Imaging Modalities on 5-Year Net Survival of 11 Cancers in 200 Countries
This analysis describes the development of a microsimulation model of stage-specific cancer survival in 200 …
This analysis describes the development of a microsimulation model of stage-specific cancer survival in 200 countries/territories for 11 cancers (oesophagus, stomach, colon, rectum, anus, liver, pancreas, lung, breast, cervix uteri, and prostate). The paper estimated current 5-year net survival for diagnosed cancers in each country and potential survival gains from increasing the availability of individual treatment and imaging modalities, and more comprehensive packages of scale-up. Global 5-year net survival for all 11 cancers (combined) is…
Global | Priority Setting/Ethics | Health Outcomes | Microsimulation | Calibration/Validation | Chronic Disease/Risk | Health Systems -
ArticlePublication 2020Role and Contribution of Treatment and Imaging Modalities in Global Cervical Cancer Management
Using a microsimulation model of global cancer survival, this analysis estimates the impact of scaling …
Using a microsimulation model of global cancer survival, this analysis estimates the impact of scaling up treatment and imaging modalities on cervical cancer survival in 200 countries/territories. The paper evaluates the potential survival effect of scaling up treatment (chemotherapy, surgery, radiotherapy, and targeted therapy), and imaging modalities (ultrasound, x-ray, CT, MRI, PET, and single photon emission CT [SPECT]) to the mean level of high-income countries, both individually and in combination. The model estimates that global…
Global | Priority Setting/Ethics | Health Outcomes | Microsimulation | Chronic Disease/Risk | Health Systems -
ArticlePublication 2021Global Costs, Health Benefits, & Economic Benefits of Scaling Up Treatment and Imaging Modalities for Survival of 11 Cancers
This analysis estimated the costs and lifetime health and economic benefits of scaling up imaging …
This analysis estimated the costs and lifetime health and economic benefits of scaling up imaging and treatment modality packages on cancer survival in 200 countries/territories for patients diagnosed with one of 11 cancers (oesophagus, stomach, colon, rectum, anus, liver, pancreas, lung, breast, cervix uteri, and prostate). Using a microsimulation model of global cancer survival, the paper evaluated the costs and health and economic benefits of scaling up packages of treatment (chemotherapy, surgery, radiotherapy, and targeted…
Global | Priority Setting/Ethics | Health Outcomes | Microsimulation | Benefit-Cost Analysis | Chronic Disease/Risk | Health Systems -
ArticlePublication 2021Impact of Treatment and Imaging Modalities on Global Breast Cancer Survival
This analysis used a microsimulation model of global cancer survival to simulate 5-year net survival …
This analysis used a microsimulation model of global cancer survival to simulate 5-year net survival for women with newly diagnosed breast cancer in 200 countries/territories in 2018, accounting for the availability and stage-specific survival impact of specific treatment modalities (chemotherapy, radiotherapy, surgery, and targeted therapy), imaging modalities (ultrasound, x-ray, CT, MRI, PET, and single-photon emission computed tomography [SPECT]), and quality of cancer care. The model was calibrated to empirical data on 5-year net breast cancer…
Global | Health Outcomes | Microsimulation | Calibration/Validation | Chronic Disease/Risk | Health Systems | Clinical Care -
ArticlePublication 2014Step-by-Step Guideline for Disease-Specific Costing Studies in LMIC
Disease-specific costing studies can be used as input into cost-effectiveness analyses and provide important information …
Disease-specific costing studies can be used as input into cost-effectiveness analyses and provide important information for efficient resource allocation. This paper provides a step-by-step guideline for conducting disease-specific costing studies in LMICs where data availability is limited and illustrates how the guideline was applied in a costing study of cardiovascular disease prevention care in rural Nigeria. The step-by-step guideline provides practical recommendations on methods and data requirements for six sequential steps: 1) definition of the study…
Sub-Saharan Africa | Costing Methods | Chronic Disease/Risk | Health Systems | Health/Medicine -
ArticlePublication 2022Healthcare Cost of Overweight & Obesity in South Africa
This analysis estimates the healthcare cost associated with treatment of weight-related conditions from the perspective …
This analysis estimates the healthcare cost associated with treatment of weight-related conditions from the perspective of the South African public sector payer. The authors report that the total cost of overweight and obesity is estimated to be ZAR33,194 million in 2020, representing approximately 15% of government health expenditure and equivalent to 0.67% of GDP. This analysis is an example of a bottom-up gross costing approach. The study draws South African data from multiple sources to estimate…
Sub-Saharan Africa | Costing Methods | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health Systems | Health/Medicine -
ArticlePublication 2022Priority Setting in Early Childhood Development: An Analytical Framework
Early childhood development (ECD) sets the foundation for healthy and successful lives with important consequences …
Early childhood development (ECD) sets the foundation for healthy and successful lives with important consequences for education, labor market outcomes, and other domains of well-being. Even though many ECD interventions are implemented and evaluated globally, there is currently no standardized framework for comparing these interventions’ relative cost-effectiveness. The investigators developed an economic evaluation framework that focuses on the immediate impact of ECD interventions targeting motor, cognitive, language, and socioemotional skills. They applied the framework to compute…
Global | Priority Setting/Ethics | Decision Analysis | Cost-Effectiveness Analysis | Child/Nutrition -
ArticlePublication 2022Hospitalization Costs for COVID-19 in Ethiopia: Empirical Data and Analysis from Addis Ababa's Largest Dedicated Treatment Center
This study examines the comprehensive costs of hospitalization for COVID-19 disease at Ekka Kotebe COVID-19 …
This study examines the comprehensive costs of hospitalization for COVID-19 disease at Ekka Kotebe COVID-19 treatment center in Addis Ababa, Ethiopia, the largest dedicated hospital for COVID-19 patient care in the country. Through retrospective collection and analysis of clinical and cost data from March to November 2020, including personnel time, drugs, medical supplies, and facility utilities, the study estimates the cost per treated COVID-19 episode stratified by disease severity. Over the study period, 2,543 COVID-19…
Sub-Saharan Africa | Costing Methods | Infectious Diseases | Health/Medicine -
ArticlePublication 2022Potential Distributional Health & Financial Benefits of Increased Tobacco Taxes in Ethiopia: Findings from a Modeling Study
This study evaluates the potential impacts of Ethiopia's tobacco tax increase in 2020, which raised …
This study evaluates the potential impacts of Ethiopia's tobacco tax increase in 2020, which raised cigarette prices by approximately 67%. Employing parameters such as price elasticity of demand and smoking prevalence, the analysis utilizes existing literature and secondary data to model the effects of the reform on various outcomes, focusing on life years, tax revenues, cigarette expenditures, and catastrophic health expenditures (CHE). Concentrating solely on male smokers due to low female smoking rates, the results…
Sub-Saharan Africa | Health Outcomes | Mathematical Models | Cost-Effectiveness Analysis | Policy/Regulation | Health/Medicine