Resources Repository
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ReviewPublication 2017Validation and Calibration of Structural Models that Combine Information from Multiple Sources
This is a review of calibration and validation methods in mathematical modeling. Such models that …
This is a review of calibration and validation methods in mathematical modeling. Such models that attempt to capture structural relationships between their components and combine information from multiple sources are increasingly used in medicine. The authors provide an overview of methods for model validation and calibration and survey studies comparing alternative approaches. Model validation entails a confrontation of models with data, background knowledge, and other models, and can inform judgments about model credibility. Calibration involves…
Mathematical Models | Calibration/Validation | Health/Medicine -
ReviewPublication 2011Simulation Models of Obesity: A Review of the Literature
Simulation models combine information from a variety of sources to provide a useful tool for …
Simulation models combine information from a variety of sources to provide a useful tool for examining how the effects of obesity unfold over time and impact population health. They can aid in the understanding of the complex interaction of the drivers of diet and activity and their relation to health outcomes. This paper provided an overview of different types of simulation models used to evaluate the potential impact of policies to address the obesity epidemic.…
Mathematical Models | Calibration/Validation | State-Transition | Microsimulation | Decision Analysis | Cost-Effectiveness Analysis | Child/Nutrition | Chronic Disease/Risk | Economics/Finance | Food/Agriculture | Health/Medicine -
ReviewPublication 2010Validation of Population-Based Disease Simulation Models: A Review
This article develops a framework for validating population-based chronic disease simulation models, and reviews the …
This article develops a framework for validating population-based chronic disease simulation models, and reviews the principles and methods for such models. While computer simulation models are used increasingly to support public health research and policy, questions about their quality persist. Based on the review, the authors formulated a set of recommendations for gathering evidence of model credibility. They find that evidence of model credibility derives from examining: 1) the process of model development, 2) the…
Mathematical Models | Calibration/Validation | Chronic Disease/Risk | Social Determinants | Health/Medicine -
ReviewPublication 2008Modeling Cervical Cancer Prevention in Developed Countries
Decision-analytic models are increasingly developed to simulate disease burden and interventions in different settings in …
Decision-analytic models are increasingly developed to simulate disease burden and interventions in different settings in order to evaluate the benefits and cost-effectiveness of primary and secondary interventions. This article is a review of mathematical models that have been used to evaluate HPV vaccination in the context of developed countries with existing screening programs. Despite variations in model assumptions and uncertainty in existing data, pre-adolescent vaccination of females in the setting of current screening practices has…
Mathematical Models | Calibration/Validation | State-Transition | Dynamic Transmission | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Health/Medicine | Science/Technology -
ReportPublication 2003ISPOR Task Force Report: Good Practice for Decision Analytic Modeling in Health-Care
This report describes the consensus of a task force convened to provide modelers with guidelines …
This report describes the consensus of a task force convened to provide modelers with guidelines for conducting and reporting modeling studies. While published more than a decade ago, it remains a clearly written resource for thinking about how to accurately describe the components of models and their quality. Criteria for assessing the quality of models fell into three areas: model structure, data used as inputs to models, and model validation. Several major themes cut across…
Mathematical Models | Calibration/Validation | Health/Medicine | Science/Technology | Global -
ReviewPublication 2023Handbook of Vaccine Health Economics
The open-access book, "Handbook of Applied Health Economics in Vaccines," looks at the complexities of …
The open-access book, "Handbook of Applied Health Economics in Vaccines," looks at the complexities of vaccine discovery, financing, and distribution. It highlights the inadequacy of standard economic models for vaccines. The book explores alternative principles challenging market-based approaches and equips readers with tools for assessing costs and benefits through practical exercises. It serves as a comprehensive resource for decision-making in vaccine development and distribution and emphasizes the importance of considering broader perspectives beyond economic efficiency.…
Benefit-Cost Analysis | Costing Methods | Health Outcomes | Evidence Synthesis | Decision Analysis | Cost-Effectiveness Analysis | Policy/Regulation | Health/Medicine | Global | Graduate | Doctoral | Professional -
ReportPublication 2021Valuing COVID-19 Mortality and Morbidity Risks
In this report, the researchers develop an approach for valuing COVID-19 mortality and morbidity risk …
In this report, the researchers develop an approach for valuing COVID-19 mortality and morbidity risk reductions that builds on the U.S. Department of Health and Human Services (HHS) Guidelines for Regulatory Impact Analysis. They review the differences between COVID-19 mortality risks and the types of risks that are more commonly studied, and find that the impacts of these differences on the value of mortality risk reductions (the value per statistical life, VSL) are uncertain. They…
Benefit-Cost Analysis | Preferences/Values | Infectious Diseases | Policy/Regulation | Government/Law | North America -
ReportPublication 2019Reference Case Guidelines for BCA in Global Health and Development
The "Benefit‐Cost Analysis Reference Case: Principles, Methods, and Standards" project, with support from the Bill …
The "Benefit‐Cost Analysis Reference Case: Principles, Methods, and Standards" project, with support from the Bill & Melinda Gates Foundation, culminates in the final “Reference Case Guidelines for Benefit-Cost Analysis in Global Health and Development.” These guidelines aim to facilitate the utilization and effectiveness of benefit-cost analysis by providing clarity on essential concepts, aiding implementation, and suggesting default values for key parameters, along with options for standardized sensitivity analysis. Targeted at practitioners with economic evaluation expertise…
Benefit-Cost Analysis | Health/Medicine | Global -
ReportPublication 2017DCP3: Improving Health and Reducing Poverty
This report from the World Bank is the ninth and final volume of the Disease …
This report from the World Bank is the ninth and final volume of the Disease Control Priorities, Third Edition (DCP3) series. It provides an overview of the findings and methods explored in the first eight volumes, placing them within a framework that identifies an efficient pathway toward essential universal health coverage through the implementation of 21 essential packages that include health interventions and fiscal and intersectoral policies. The Disease Control Priorities Network (DCP) promotes and…
Benefit-Cost Analysis | Costing Methods | Health Outcomes | Evidence Synthesis | Cost-Effectiveness Analysis | Infectious Diseases | Maternal/Reproductive Health | Child/Nutrition | Chronic Disease/Risk | Mental Health | Injuries/Accidents | Social Determinants | Health Systems | Policy/Regulation | Global Governance | Economics/Finance | Government/Law | Health/Medicine | Science/Technology | Global