Resources Repository
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ReviewPublication 2008Modeling Cervical Cancer Prevention in Developed Countries
Decision-analytic models are increasingly developed to simulate disease burden and interventions in different settings in …
Decision-analytic models are increasingly developed to simulate disease burden and interventions in different settings in order to evaluate the benefits and cost-effectiveness of primary and secondary interventions. This article is a review of mathematical models that have been used to evaluate HPV vaccination in the context of developed countries with existing screening programs. Despite variations in model assumptions and uncertainty in existing data, pre-adolescent vaccination of females in the setting of current screening practices has…
Calibration/Validation | Dynamic Transmission | State-Transition | Science/Technology | Mathematical Models | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Health/Medicine -
Resource PackPublication, Teaching Resource 2018Resource Pack: Models for Health Decision Science
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to …
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to mathematical models used in health decision science (e.g., microsimulation, dynamic transmission, agent-based, etc.). Resources include overviews, guidelines, tutorials, and applications relevant to a broad range of clinical and public health topics. A decision analytic approach relies on the use of a mathematical model to formally structure the components of the decision over time. Models are particularly useful when multiple data sources…
Dynamic Transmission | State-Transition | Science/Technology | Mathematical Models | Microsimulation | Dynamic Simulation | Climate/Environment | Economics/Finance | Health/Medicine -
Resource PackPublication, Teaching Resource 2023Resource Pack: Books on Decision Making and Thinking
This resource pack, curated by the Center for Health Decision Science, features books about how …
This resource pack, curated by the Center for Health Decision Science, features books about how we think, learn, and decide. We aim to provide an introduction to some of the core concepts in decision theory and psychology with this collection, and hope that it will stimulate further inquiry. These books are geared to a general audience; the majority are very accessible reads. The collection is broadly divided into three categories. The first is made up of…
Decision Psychology | Business/Industry | Science/Technology | Decision Theory | Probability/Bayes | Preferences/Values | Climate/Environment | Culture/Society | Economics/Finance | Health/Medicine | Global | High School | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Policy Translation -
ArticlePublication 2013Estimated Mortality Impact of Vaccinations 2011–2020 in 73 GAVI Alliance Countries
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted …
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted by the GAVI Alliance and the Bill & Melinda Gates Foundation to estimate the impact of vaccination in 73 countries supported by the GAVI Alliance. The number of deaths averted in persons projected to be vaccinated during 2011–2020 was estimated for ten antigens: hepatitis B, yellow fever, Haemophilus influenzae type B (Hib), Streptococcus pneumoniae, rotavirus, Neisseria meningitidis serogroup A, Japanese…
Dynamic Transmission | State-Transition | Science/Technology | Health Outcomes | Mathematical Models | Microsimulation | Infectious Diseases | Global Governance | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
BookPublication 2010Predictably Irrational: The Hidden Forces That Shape Our Decisions
This book explores the “hidden forces” that shape decisions as an argument against the common …
This book explores the “hidden forces” that shape decisions as an argument against the common assumption that people act in fundamentally rational ways. From drinking coffee to losing weight, people consistently overpay, underestimate, and procrastinate. Ariely shows that such misguided behaviors are systematic and predictable or “predictably irrational.”
Decision Psychology | Business/Industry | Science/Technology | Culture/Society | Economics/Finance | Education/Labor | Health/Medicine -
ArticlePublication 2008Health and Economic Implications of HPV Vaccination in the U.S.
This article reports on a study using models of HPV-16 and HPV-18 transmission and cervical …
This article reports on a study using models of HPV-16 and HPV-18 transmission and cervical carcinogenesis to compare the health and economic outcomes of vaccinating preadolescent girls in the US (at 12 years of age), and vaccinating older girls and women in catch-up programs (to 18, 21, or 26 years of age). The study also examined the health benefits of averting other HPV-16-related and HPV-18-related cancers, the prevention of HPV-6-related and HPV-11-related genital warts and…
Calibration/Validation | Dynamic Transmission | Science/Technology | Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Clinical Care | Economics/Finance | Health/Medicine | North America -
ArticlePublication 2008Mathematical Models of Cervical Cancer Prevention in Latin America and the Caribbean
This article reports on a model-based approach estimated averted cervical cancer cases and deaths, disability-adjusted …
This article reports on a model-based approach estimated averted cervical cancer cases and deaths, disability-adjusted life years (DALYs) and incremental cost-effectiveness ratios (I$/DALY averted) for human papillomavirus (HPV) vaccination of young adolescent girls using population and epidemiologic data for 33 countries in Latin America and the Caribbean (LAC). The authors found that an absolute reduction in lifetime cancer risk varied between countries, depending on incidence, proportion attributable to HPV-16 and 18, and population age-structure; for…
Calibration/Validation | State-Transition | Science/Technology | Costing Methods | Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Latin America & Caribbean -
ReviewPublication 2008Cost-Effectiveness of Vaccination: Review of Modelling Approaches
This review examines the modelling approaches used in cost-effectiveness analyses (CEAs) of vaccination programs. After …
This review examines the modelling approaches used in cost-effectiveness analyses (CEAs) of vaccination programs. After overviewing the key attributes of models used in CEAs, a framework for categorizing theoretical models is presented. Categories are based on three main attributes: static/dynamic; stochastic/deterministic; and aggregate/individual based.
Dynamic Transmission | State-Transition | Science/Technology | Mathematical Models | Microsimulation | Dynamic Simulation | Cost-Effectiveness Analysis | Infectious Diseases | Health/Medicine | Global -
ArticlePublication 2023Benefits and Costs of COVID-19 Vaccine Mandates
Written mid-pandemic, this article evaluates the direct costs and health benefits of requiring COVID-19 vaccinations …
Written mid-pandemic, this article evaluates the direct costs and health benefits of requiring COVID-19 vaccinations for U.S. federal employees and healthcare and private sector workers. These mandates were controversial and some were halted by litigation. If they had been implemented as intended, the net benefits would depend on the course of the pandemic. If a more transmissible variant (such as Omicron) emerges, the net benefits may be large. If the pandemic instead fades, the benefits…
State-Transition | Business/Industry | Mathematical Models | Benefit-Cost Analysis | Infectious Diseases | Policy/Regulation | Economics/Finance | Government/Law | Health/Medicine | North America