Resources Repository
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OrganizationPublication 2024Based on Science
Since President Lincoln signed a congressional charter forming the National Academy of Sciences in 1863, …
Since President Lincoln signed a congressional charter forming the National Academy of Sciences in 1863, the National Academies have served the nation by drawing on the knowledge of the country’s top experts to deliver nonpartisan, objective advice on scientific matters. Based On Science uses the community of experts to provide the most up-to-date, evidence-based information about science and health questions that affect the decisions we make each day. This description was extracted from the Based…
Climate/Environment | Science/Technology | Evidence Synthesis | Culture/Society | Energy/Engineering | Education/Labor | Health/Medicine | North America -
ReviewPublication 2021European News Consumers' Perceptions of Misinformation
This study indicated that news users across ten different European countries are quite concerned about …
This study indicated that news users across ten different European countries are quite concerned about misinformation in their information environment. Respondents were most likely to associate politicians, corporations, and foreign actors with misinformation. They perceived misinformation to be most common for topics like immigration, the economy, and the environment. This offered support for the increasingly more relative and politicized status of facts in people’s credibility perceptions. Yet, differences across sources and issues were relatively modest,…
Preferences/Values | Decision Psychology | Science/Technology | Social Determinants | Culture/Society | Education/Labor | Health/Medicine | Europe -
ReviewPublication 2016Strengthening Cost-Effectiveness Analysis for Public Health Policy
Many important opportunities to improve health lie outside the health sector and involve improving the …
Many important opportunities to improve health lie outside the health sector and involve improving the conditions in which we live and work: safe design and maintenance of roads, bridges, train tracks, and airports; control of environmental pollutants; occupational safety; healthy buildings; a safe and healthy food supply; safe manufacture of consumer products; a healthy social environment; and others. Faced with the overwhelming array of possibilities, U.S. decision makers need help identifying those that can contribute the…
Preferences/Values | Climate/Environment | Priority Setting/Ethics | Costing Methods | Cost-Effectiveness Analysis | Social Determinants | Environmental Health | Health Systems | Policy/Regulation | Economics/Finance | Food/Agriculture | Health/Medicine | North America -
ReviewPublication 2023Inclusion of Environmental Spillovers in Applied Economic Evaluations of Healthcare Products
This review examines the inclusion of environmental spillovers in economic evaluations of healthcare products and …
This review examines the inclusion of environmental spillovers in economic evaluations of healthcare products and health technology assessments (HTA). Environmental spillovers, such as CO2 emissions, water and energy consumption, and waste disposal, significantly impact human and planetary health but are often excluded from HTAs. The review's objective is to identify economic evaluations and guidelines incorporating environmental dimensions. Methods included electronic searches of PubMed, Scopus, and EMBASE, as well as official health agencies' guidelines. Documents were…
Climate/Environment | Evidence Synthesis | Cost-Effectiveness Analysis | Technology Assessment | Environmental Health | Health/Medicine | Global -
ReviewPublication 2021Considerations for Diagnostic COVID-19 Tests
During the initial stages of the COVID-19 pandemic, there was a rush by numerous diagnostic …
During the initial stages of the COVID-19 pandemic, there was a rush by numerous diagnostic test manufacturers to create, validate, and implement testing methods. This review discusses the pivotal role of diagnostic tests during the pandemic's first global wave, highlighting the challenges in technology and implementation experienced early on. The study also offers insights for enhancing the use of diagnostics, especially syndromic ones, should there be future spikes or regional outbreaks of COVID-19. The overarching…
Test Performance | Science/Technology | Infectious Diseases | Clinical Care | Health/Medicine | North America -
ReviewPublication 2022Rapid, Point-of-Care Antigen Tests for Diagnosis of SARS-CoV-2 Infection
This study reviewed the diagnostic accuracy of rapid, point-of-care antigen tests for detecting SARS-CoV-2 infection, …
This study reviewed the diagnostic accuracy of rapid, point-of-care antigen tests for detecting SARS-CoV-2 infection, differentiating results between symptomatic and asymptomatic individuals. Using data from 155 study cohorts, the study found that the sensitivity of antigen tests was generally higher for symptomatic individuals, especially during the first week after symptom onset, due to higher viral loads. For example, average sensitivity was higher in symptomatic (73.0%) compared to asymptomatic participants (54.7). Average sensitivity was higher in…
Test Performance | Science/Technology | Infectious Diseases | Clinical Care | Health/Medicine | North America -
ReviewPublication 2022Significance of Advanced COVID-19 Diagnostic Testing in Pandemic Control Measures
Over the past two years of the COVID-19 pandemic, the scientific community has mounted significant …
Over the past two years of the COVID-19 pandemic, the scientific community has mounted significant efforts to combat the highly transmissible SARS-CoV-2 virus. Despite substantial progress in vaccines and treatments, leading to lower hospitalization and death rates, the virus has continued to evolve, primarily through mutations. From the onset, diagnostic tests have been crucial in identifying and controlling the virus spread. The scientific world has pioneered various diagnostic techniques, including nucleic acid, antigen, and antibody-based…
Test Performance | Science/Technology | Infectious Diseases | Health Systems | Clinical Care | Health/Medicine | North America -
ReviewPublication 2022Diagnostics for COVID-19: Moving from Pandemic Response to Control
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 …
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 infections. Each test type remains vital as we shift from responding to controlling the pandemic. Molecular tests, like PCR, are highly precise in identifying viral RNA and are endorsed by the WHO for confirming cases and guiding public health actions. Antigen rapid tests spot viral proteins and, while less accurate than molecular tests, are quicker, more affordable, simpler, and can…
Test Performance | Science/Technology | Infectious Diseases | Health Systems | Clinical Care | Health/Medicine -
ReviewPublication 2016Choosing an Epidemiological Model Structure for Economic Evaluation
This review presents a taxonomy of epidemiological model structures and applies it to the economic …
This review presents a taxonomy of epidemiological model structures and applies it to the economic evaluation of public health interventions for non-communicable diseases. Growing pressures on health services and on social care have led to a greater need for prevention of chronic diseases. In order for decision makers to make informed judgements about how to best spend finite public health resources, they must be able to quantify the anticipated costs, benefits, and opportunity costs of…
Dynamic Transmission | Climate/Environment | Mathematical Models | State-Transition | Microsimulation | Dynamic Simulation | Chronic Disease/Risk | Social Determinants | Environmental Health | Health Systems | Culture/Society | Health/Medicine