Resources Repository
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ArticlePublication 2021Measuring the Impact of COVID-19 Vaccine Misinformation on Vaccination Intent in the U.K. and U.S.
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight …
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight the COVID-19 pandemic, but high uptake achievement will be a challenge and may be impeded by online misinformation. This article is a randomized controlled trial in the U.K. and the U.S. with the objective to quantify how exposure to online misinformation around COVID-19 vaccines affects intent to vaccinate to protect oneself or others. The authors report that in both countries…
Infectious Diseases | Europe | Social Determinants | Decision Psychology | Preferences/Values | Child/Nutrition | Culture/Society | Health/Medicine | Science/Technology | North America -
ArticlePublication 2018DALYS and QALYs – Does the Choice of Measure Matter?
This article discusses the measurement of health benefits as a key issue in health economic …
This article discusses the measurement of health benefits as a key issue in health economic evaluations. Authors adapted two previously published models, a Markov model for human papilloma virus (HPV) vaccination, and a pneumococcal vaccination deterministic model (PNEUMO) that reported outputs in QALYs to estimate DALYs in 3 settings, Argentina, Chile, and the United Kingdom. While the authors found that QALY gains were larger than DALYs avoided in all countries for HPV, differences using QALYs…
Infectious Diseases | Latin America & Caribbean | Europe | Cost-Effectiveness Analysis | Policy/Regulation | Health/Medicine -
DataWeb Portal 2024OECD Health Statistics
The Organisation for Economic Co-operation and Development (OECD) Health Database offers a comprehensive source of …
The Organisation for Economic Co-operation and Development (OECD) Health Database offers a comprehensive source of comparable statistics on health and health systems across OECD countries. These data serve to facilitate and support comparative analyses, and can be useful for researchers, educators and policy makers looking to draw lessons from international comparisons of diverse health systems. General categories of data include population demographics, health status and determinants of health, as well as data on the societal responses to health…
Latin America & Caribbean | Europe | Social Determinants | Health Outcomes | Maternal/Reproductive Health | Child/Nutrition | Chronic Disease/Risk | Mental Health | Health Systems | Policy/Regulation | Economics/Finance | Education/Labor | Health/Medicine | Science/Technology | North America | Oceania -
ArticlePublication 2022Spatial-Mechanistic Model to Estimate Sub-National Tuberculosis Burden in Brazilian Municipalities
Reliable subnational estimates of TB incidence are needed to focus disease control resources in areas …
Reliable subnational estimates of TB incidence are needed to focus disease control resources in areas of highest need. This study developed an approach for generating small area estimates of TB incidence, and the fraction of individuals missed by routine case detection, based on available notification and mortality data. The approach is demonstrated by estimating TB outcomes for 5568 municipalities in Brazil, revealing substantial subnational differences in disease burden and other metrics useful for designing high-impact…
Infectious Diseases | Latin America & Caribbean | Health Outcomes | Mathematical Models | Health/Medicine -
ArticlePublication 2022Emerging Therapies for COVID-19: The Value of Information From More Clinical Trials
The COVID-19 pandemic necessitated time-sensitive policy and implementation decisions regarding new therapies in the face …
The COVID-19 pandemic necessitated time-sensitive policy and implementation decisions regarding new therapies in the face of uncertainty. This study aimed to quantify consequences of approving therapies or pursuing further research. The authors used a cohort state-transition model for hospitalized patients with COVID-19 to estimate quality-adjusted life-years (QALYs) and costs associated with multiple drug regimens and usual care. For each they assessed immediate approval, use only in research, emergency use authorization or reject. They conducted cost-effectiveness…
Infectious Diseases | Europe | Value of Information | State-Transition | Benefit-Cost Analysis | Policy/Regulation | Economics/Finance | North America -
ArticlePublication 2022Early HPV Natural History Transitions
Microsimulation models used to evaluate the cost-effectiveness of novel cervical cancer screening technologies rely on …
Microsimulation models used to evaluate the cost-effectiveness of novel cervical cancer screening technologies rely on accurate transition risks for human papillomavirus (HPV) infection, persistence (or absence of HPV clearance), progression to precancerous lesions, and invasion. To inform the refinement of such models, we compared the early natural history of HPV types using prospective data from immunocompetent women in the Guanacaste Natural History Study, the ASCUS-LSIL Triage Study, and the Costa Rica HPV Vaccine Trial. We…
Infectious Diseases | Latin America & Caribbean | Mathematical Models | Microsimulation | Cost-Effectiveness Analysis | North America -
ArticlePublication 2021Impact of COVID-19 on Cancer Diagnosis and Survival in Chile
This paper estimates the impact of the COVID-19 pandemic on delays in cancer diagnosis in …
This paper estimates the impact of the COVID-19 pandemic on delays in cancer diagnosis in Chile, using a microsimulation model of five cancers: breast, cervix, colorectal, prostate, and stomach. The model simulates cancer incidence and progression, as well as stage-specific cancer detection and survival probabilities, and was calibrated to empirical data on monthly detected cases, stage at diagnosis, and 5-year net survival. The analysis accounted for the impact of COVID-19 on month-by-month excess mortality and…
Infectious Diseases | Latin America & Caribbean | Health Outcomes | Microsimulation | Calibration/Validation | Chronic Disease/Risk -
ReviewPublication 2021European News Consumers' Perceptions of Misinformation
This study indicated that news users across ten different European countries are quite concerned about …
This study indicated that news users across ten different European countries are quite concerned about misinformation in their information environment. Respondents were most likely to associate politicians, corporations, and foreign actors with misinformation. They perceived misinformation to be most common for topics like immigration, the economy, and the environment. This offered support for the increasingly more relative and politicized status of facts in people’s credibility perceptions. Yet, differences across sources and issues were relatively modest,…
Europe | Social Determinants | Decision Psychology | Preferences/Values | Culture/Society | Education/Labor | Health/Medicine | Science/Technology -
Resource PortalWeb Portal, Teaching Resource 2024Millennium Mathematics Project (MMP)
The Millennium Mathematics Project (MMP), a collaboration between the Faculties of Mathematics and Education at the …
The Millennium Mathematics Project (MMP), a collaboration between the Faculties of Mathematics and Education at the University of Cambridge, is a maths education and outreach initiative for ages 3 to 19 and the general public. The focus is on increasing mathematical understanding, confidence and enjoyment, developing problem-solving skills, and promoting creative and imaginative approaches to maths. The project consists of a family of complementary programmes, including the NRICH website, Plus online mathematics magazine, Wild Maths, and…
Infectious Diseases | Europe | Probability/Bayes | Test Performance | Mathematical Models | Decision Analysis | Risk Analysis | Child/Nutrition | Environmental Health | Health/Medicine | Science/Technology | High School | College | Graphics/Visualization | Quantitative Literacy