Resources Repository
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ArticlePublication 2023Single-Arm Trial Design Estimates Efficacy
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and …
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and of vaccination modifications are needed, but randomized controlled trials are costly and face logistical and ethical challenges. In this study, the authors demonstrate proof-of-principle that a single-arm design yields valid estimates with similar precision to a randomized controlled trial.
Maternal/Reproductive Health | Health Outcomes | Infectious Diseases | Policy/Regulation | Health/Medicine | Global -
ArticlePublication 2023Effects of Public Financing of Essential Maternal and Child Health Interventions Across Wealth Quintiles in Nigeria: An Extended Cost-Effectiveness Analysis
This study evaluates the potential health and financial risk protection benefits of public financing for …
This study evaluates the potential health and financial risk protection benefits of public financing for maternal, newborn, and child health (MNCH) interventions in Nigeria, focusing on different wealth quintiles. Employing extended cost-effectiveness analysis, the research assesses the impact of a policy ensuring zero out-of-pocket costs for 18 essential MNCH services. Three scenarios were modeled: status quo, uniform scale-up, and pro-poor scale-up. Findings suggest that a 5% increase in coverage for all quintiles could prevent significant…
Maternal/Reproductive Health | Health Outcomes | Mathematical Models | Cost-Effectiveness Analysis | Policy/Regulation | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2022WHO ACTION-I Trial in Low Resource Countries
This study evaluated the cost-effectiveness of dexamethasone administration in dexamethasone in pregnant women at risk …
This study evaluated the cost-effectiveness of dexamethasone administration in dexamethasone in pregnant women at risk of early preterm birth using data from a multicentre, randomized, placebo-controlled trial in Bangladesh, India, Kenya, Nigeria, and Pakistan. Primary cost data were collected in 28 hospitals across the 5 countries. A decision tree model was used to compare dexamethasone treatment to no intervention from a health-care sector perspective. Administration of dexamethasone averted 38 neonatal deaths per 1000 woman–baby units…
Maternal/Reproductive Health | Health Outcomes | Mathematical Models | Cost-Effectiveness Analysis | Child/Nutrition | Clinical Care | Global | Sub-Saharan Africa | Asia & Pacific -
ArticlePublication 2019Estimation of Eating Disorders Prevalence by Age and Associations with Mortality in a Simulated Nationally Representative U.S. Cohort
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, …
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, and estimates the association of increased treatment coverage with ED-related mortality. Using an individual-level Markov state transition model calibrated to nationally-representative US survey data from 2007 and 2011, the authors simulated a virtual cohort of 100,000 individuals (50% male) from birth to age 40 years and modelled 4 ED diagnoses: anorexia nervosa, bulimia nervosa, binge eating disorder, and other specified…
Mental Health | Health Outcomes | Microsimulation | Calibration/Validation | Child/Nutrition | North America -
Tools/ModelsWeb Portal, Teaching Resource 2019Australia & New Zealand Health Intervention Interactive League Table
This interactive league table contains more than 800 Australian and New Zealand evaluations of public …
This interactive league table contains more than 800 Australian and New Zealand evaluations of public health intervention impacts on health gains (in quality/disability/health adjusted life years), health system costs and cost effectiveness. It allows users (policy-makers, researchers, health professionals, general public) to compare the health gains and costs associated with different interventions. The web portal provides access to a Users Guide and a Plain Language Summary of how to interpret table and graph outputs. Read the research…
Mental Health | Priority Setting/Ethics | Health Outcomes | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Health/Medicine | Asia & Pacific | Oceania | College | Graduate | Doctoral | Professional | Graphics/Visualization -
ArticlePublication 2022Comparing Health Gains, Costs & Cost-Effectiveness of Interventions in Australia & New Zealand
This paper synthesizes the health gains, costs, and cost-effectiveness of health interventions in Australia and New …
This paper synthesizes the health gains, costs, and cost-effectiveness of health interventions in Australia and New Zealand (NZ) from studies conducted with comparable methods, and reports results in the form of an online interactive league table. Studies from the Australia Cost-Effectiveness research and NZ Burden of Disease Epidemiology, Equity and Cost-Effectiveness Programmes and studies were included which reported health-adjusted life years (HALYs) and net health system costs and/or incremental cost-effectiveness ratios, used a time horizon of…
Mental Health | Priority Setting/Ethics | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Health/Medicine | Asia & Pacific | Oceania -
ArticlePublication 2021Using Health Management Information System Data: Case Study and Verification of Institutional Deliveries in Ethiopia
This article investigates the quality of Health Management Information Systems (HMIS) data in Ethiopia through …
This article investigates the quality of Health Management Information Systems (HMIS) data in Ethiopia through a data verification study, aiming to enhance its utility in research and policy. By linking HMIS data to the 2016 Emergency Obstetric and Newborn Care Assessment, the study compares reported delivery and caesarean section (C-section) visits in HMIS to source documents from 2,425 health facilities across Ethiopia. Findings indicate that two-thirds of facilities exhibit 'good' HMIS reporting for deliveries, with…
Maternal/Reproductive Health | Health Systems | Health/Medicine | Sub-Saharan Africa -
OrganizationWeb Portal 2024RAND Corporation
The RAND Corporation (“Research and Development”) is a research organization that develops solutions to public …
The RAND Corporation (“Research and Development”) is a research organization that develops solutions to public policy challenges to help make communities throughout the world safer and more secure, healthier and more prosperous. RAND is nonprofit, nonpartisan, and committed to the public interest. RAND’s research findings and recommendations are based on data and evidence and therefore do not necessarily reflect the policy preferences or interests of its clients, donors, or…
Environmental Health | Child/Nutrition | Injuries/Accidents | Policy/Regulation | Business/Industry | Climate/Environment | Energy/Engineering | Education/Labor | Government/Law | Health/Medicine | Military/Defense | Science/Technology | Global -
ArticlePublication 2020Premature Deaths, Statistical Lives, and Years of Life
This article clarifies some misconceptions about mortality risk and economic valuation. The mortality effects of …
This article clarifies some misconceptions about mortality risk and economic valuation. The mortality effects of exposure to environmental hazards such as air pollution are often described by the estimated number of “premature deaths” and the economic value of an exposure reduction as the number of “statistical lives saved” multiplied by the “value per statistical life.” These terms can be misleading because the number of deaths advanced by exposure cannot be determined from mortality data; it…
Environmental Health | Preferences/Values | Health Outcomes | Benefit-Cost Analysis | Policy/Regulation | College | Graduate | Critical Thinking/Analysis