Resources Repository
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ArticlePublication 2023Single-Arm Trial Design Estimates Efficacy
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and …
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and of vaccination modifications are needed, but randomized controlled trials are costly and face logistical and ethical challenges. In this study, the authors demonstrate proof-of-principle that a single-arm design yields valid estimates with similar precision to a randomized controlled trial.
Health Outcomes | Global | Infectious Diseases | Maternal/Reproductive Health | Policy/Regulation | Health/Medicine -
ArticlePublication 2021COVID-19 Mortality and Self-Imposed Behavior Change/Government Regulations
Countries have adopted different approaches, at different times, to reduce the transmission of COVID-19. Cross-country …
Countries have adopted different approaches, at different times, to reduce the transmission of COVID-19. Cross-country comparison could indicate the relative efficacy of these approaches. This article assesses various nonpharmaceutical interventions, comparing the effects of voluntary behavior change and of changes enforced via official regulations, by examining their impacts on subsequent death rates. Voluntarily reduced mobility, occurring prior to government policies, decreases the percent change in deaths per day by 9.2% (95% confidence interval [CI] 4.5–14.0).…
Health Outcomes | Global | Infectious Diseases | Policy/Regulation -
ArticlePublication 2022Re-Evaluating the Health Impact and Cost-Effectiveness of Tuberculosis Prevention for Modern ART Cohorts
TB preventive therapy (TPT) is widely accepted to be cost-effective for reducing TB incidence in …
TB preventive therapy (TPT) is widely accepted to be cost-effective for reducing TB incidence in HIV-infected individuals receiving antiretroviral therapy (ART). However, as individuals initiate ART earlier in the course of disease, TB incidence is lower, and it is unclear how ART cost-effectiveness has changed. This study assessed the cost-effectiveness of TPT in contemporary ART cohorts. The authors developed a microsimulation model of TB and HIV and parameterised it using data from a large HIV…
Microsimulation | Global | Infectious Diseases | Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2021New Microsimulation Models to Inform Cervical Cancer Control
Health decision models consider the lifetime natural history of human papillomavirus (HPV) infection and pathogenesis …
Health decision models consider the lifetime natural history of human papillomavirus (HPV) infection and pathogenesis of cervical cancer, and estimate the long-term impact of preventive interventions. We propose a new health decision modeling framework that de-emphasizes previously used cytologic-colposcopic-histologic diagnoses, which are subjective and lack reproducibility, relying instead on HPV type and duration of infection as the major determinants of model transition probabilities. We posit that new model health states and corollary transitions are universal,…
Microsimulation | Global | Infectious Diseases | Mathematical Models | Calibration/Validation | Decision Analysis | Cost-Effectiveness Analysis -
ArticlePublication 2020Interpreting COVID-19 Test Results: A Bayesian Approach
This article considers the following question with respect to interpreting the results of polymerase chain reaction …
This article considers the following question with respect to interpreting the results of polymerase chain reaction (PCR) assays from nasal and pharyngeal swabs for COVID-19 to inform clinical decision making: "While a positive result in an acutely ill patient is straightforward, how should physicians interpret negative tests in patients with suspected COVID-19 infection?" Using an assumption of near-perfect specificity of PCR assays for COVID-19, the authors acknowledge the uncertainty of test sensitivity. They consider two clinical scenarios…
Test Performance | Global | Infectious Diseases | Probability/Bayes | Health/Medicine | Science/Technology -
DataPublication 2019Global Multidimensional Poverty Index 2019: Illuminating Inequalities
This data publication developed by the United Nations Development Programme (UNDP) and the Oxford Poverty …
This data publication developed by the United Nations Development Programme (UNDP) and the Oxford Poverty and Human Development Initiative (OPHI) offers data for 101 countries and 5.7 billion people, comparing acute multidimensional poverty at regional, national, and subnational levels using the global Multidimensional Poverty Index (MPI). The global MPI, developed by the OPHI in 2010, is one tool to comprehensively measure progress towards Sustainable Development Goal (SDG) 1, which aims to end poverty in all…
Health Outcomes | Global | Health Systems | Social Determinants | Climate/Environment | Economics/Finance | Education/Labor -
DataPublication 2019HDR Country Profile: Afghanistan
This country profile on Afghanistan is published by the United Nations Development Programme (UNDP). Each …
This country profile on Afghanistan is published by the United Nations Development Programme (UNDP). Each online country profile also links to a downloadable data table and a briefing note for its country. The Human Development Report Office releases data each year, including the Human Development Index (HDI), the Inequality-Adjusted Human Development Index (IHDI), the Gender Development Index (GDI), the Gender Inequality Index (GII), and the Multidimensional Poverty Index (MPI). These indices reflect the UNDP human…
Health Outcomes | Global | Health Systems | Evidence Synthesis | Social Determinants | Climate/Environment | Economics/Finance | Education/Labor | Health/Medicine | Science/Technology | Asia & Pacific -
DataInteractive 2018Beyond Income: A Broader Picture of Poverty
This interactive web portal, hosted by the United Nations Development Programme (UNDP), explores the multidimensional …
This interactive web portal, hosted by the United Nations Development Programme (UNDP), explores the multidimensional nature of poverty around the world. The Multidimensional Poverty Index (MPI) measures poverty across three dimensions—health, education, and living standards—and uses 10 indicators such as lacking access to clean water, adequate nutrition, or primary education. This web portal allows users to explore each of these 10 indicators through illustrative, media-rich country cases.
Health Outcomes | Global | Health Systems | Evidence Synthesis | Social Determinants | Climate/Environment | Economics/Finance | Education/Labor | Health/Medicine | Science/Technology -
DataWeb Portal 2022Global Human Development Indicators: Country Profiles
This web portal, published by the United Nations Development Programme (UNDP), provides the most recent …
This web portal, published by the United Nations Development Programme (UNDP), provides the most recent human development data for countries across the world. Topics examined range from health and education, to poverty and human security. Each online country profile also links to a downloadable data table and a briefing note for its country. The Human Development Report Office releases five indices each year: the Human Development Index (HDI), the Inequality-Adjusted Human Development Index (IHDI), the…
Health Outcomes | Global | Health Systems | Evidence Synthesis | Social Determinants | Climate/Environment | Economics/Finance | Education/Labor | Health/Medicine | Science/Technology