Resources Repository
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ReportPublication 2015Modeling to Improve Policy Decisions in the Americas: Noncommunicable Diseases
In the Region of the Americas, noncommunicable diseases (NCDs) are a clear threat not only …
In the Region of the Americas, noncommunicable diseases (NCDs) are a clear threat not only to human health, but also to a country’s economic development and growth. The evidence on both of these counts is compelling. In 2012, cardiovascular disease, diabetes, cancers, chronic respiratory conditions including asthma, and other NCDs were the cause of 4.5 million deaths in the Americas. Of that total number, 1.5 million of them were premature, occurring among people aged 30-69…
Decision Analysis | Mental Health | Microsimulation | Priority Setting/Ethics | Costing Methods | Mathematical Models | State-Transition | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health/Medicine | Latin America & Caribbean -
ArticlePublication 2006Can Discrete Event Simulation be of Use in Modeling Major Depression?
This article, published in Cost Effectiveness and Resource Allocation, reviews the published literature on Markov …
This article, published in Cost Effectiveness and Resource Allocation, reviews the published literature on Markov models in depression and identified potential limitations in using this particular modelling approach in this disease area. Additionally, the authors develop a “Discrete Event Simulation” (DES) model to investigate the benefits and drawbacks of this simulation method compared with Markov modelling techniques. The findings of this study indicate that the most important limitation of using Markov models in depression is…
Decision Analysis | Mental Health | Microsimulation | State-Transition | Health/Medicine -
ArticlePublication 2019Estimation of Eating Disorders Prevalence by Age and Associations with Mortality in a Simulated Nationally Representative U.S. Cohort
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, …
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, and estimates the association of increased treatment coverage with ED-related mortality. Using an individual-level Markov state transition model calibrated to nationally-representative US survey data from 2007 and 2011, the authors simulated a virtual cohort of 100,000 individuals (50% male) from birth to age 40 years and modelled 4 ED diagnoses: anorexia nervosa, bulimia nervosa, binge eating disorder, and other specified…
Mental Health | Microsimulation | Health Outcomes | Calibration/Validation | Child/Nutrition | North America -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Valuing Individual Health Outcomes
In this teaching pack on Valuing Individual Health Outcomes, students learn how to assign quantitative …
In this teaching pack on Valuing Individual Health Outcomes, students learn how to assign quantitative values to health outcomes at the individual level, including: expected utility theory, the axioms of this theory, distinguishing between preference-based measures of value and health-related quality of life outcomes, measuring utility using the standard gamble, the time trade-off, and the visual analog scale, and understanding the limitations of these measures. Materials include an instructor's note, videos, companion slides, a glossary,…
Decision Analysis | Injuries/Accidents | Preferences/Values | Health Outcomes | Economics/Finance | Health/Medicine | College | Graduate | Doctoral -
ReviewPublication 2017Model-Based Economic Evaluation of Treatments for Depression: A Systematic Review
This article, published in Pharmacoeconomics, systematically reviews the literature in order to identify model-based studies …
This article, published in Pharmacoeconomics, systematically reviews the literature in order to identify model-based studies evaluating the cost-effectiveness of treatments for depression and examine the appropriateness of different modelling technique for simulating the natural course of depression. The review yielded 41 model-based studies, of which 21 used decision trees (DTs), 15 used cohort-based state-transition Markov models (CMMs), two used individual-based state-transition models (ISMs), and three used discrete-event simulation (DES) models. Just over half of the…
Mental Health | Microsimulation | Mathematical Models | State-Transition | Cost-Effectiveness Analysis | Health/Medicine -
Resource PackPublication, Teaching Resource 2017Resource Pack: U.S. Opioid Epidemic
Opioid misuse and addiction in the United States is an ongoing and rapidly evolving public …
Opioid misuse and addiction in the United States is an ongoing and rapidly evolving public health crisis, requiring an urgent coordinated response and innovative scientific solutions. This resource pack was curated for educators and students interested in how decision analytic methods and tools can be applied to the problem of opioid addiction.
Decision Analysis | Mental Health | Preferences/Values | Evidence Synthesis | Mathematical Models | Cost-Effectiveness Analysis | Chronic Disease/Risk | Social Determinants | Health Systems | Policy/Regulation | Economics/Finance | Government/Law | Health/Medicine | North America | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Policy Translation -
Lesson/ModulePublication, Teaching Resource 2016Surviving the Surge
This case study explores the experiences of three Manhattan-based hospitals during Superstorm Sandy in 2012. …
This case study explores the experiences of three Manhattan-based hospitals during Superstorm Sandy in 2012. It focuses on decisions made by each institution, as Sandy approached, about whether to shelter-in-place or evacuate hundreds of medically fragile patients, and how each of the three hospitals took a different approach, informed by differing perceptions of risk and related factors. The case will be useful for public health students and administrators in understanding decision-making in settings of an…
Decision Analysis | Injuries/Accidents | Risk Analysis | Social Determinants | Environmental Health | Business/Industry | Climate/Environment | Health/Medicine | North America | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership -
Lesson/ModulePublication, Teaching Resource 2014CDC Science Ambassador Workshop 2014 Lesson Plan: Master of Disaster
This lesson plan from the Centers for Disease Control and Prevention (CDC) was curated to …
This lesson plan from the Centers for Disease Control and Prevention (CDC) was curated to teach high school students, grades 9-10, to explore decision-making around natural disaster emergencies. The lesson includes a video, public health emergency response data, and a response plan. It explores interactive cases of cholera in Haiti after an earthquake and breaks down risk factors and different approaches to the scenario. Students make informed decisions based on this data, exploring public health…
Decision Analysis | Injuries/Accidents | Environmental Health | Policy/Regulation | Climate/Environment | Culture/Society | Economics/Finance | Health/Medicine | Science/Technology | North America | Latin America & Caribbean | High School | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ArticlePublication 2012Modeling the Risks and Benefits of Depression Treatment for Children and Young Adults
This article, published in Value in Health, presents a discrete event simulation model to quantify …
This article, published in Value in Health, presents a discrete event simulation model to quantify the trade-offs with respect to clinical benefits and the risk of fatal and non-fatal suicidal behavior of alternative treatment strategies for a U.S. pediatric population with major depressive disorder. The authors evaluate treatment strategies including: selective serotonin reuptake inhibitors (SSRIs), cognitive behavioral therapy (CBT), and a combination of both. The results show that the use of SSRIs is associated with…
Mental Health | Microsimulation | Health Outcomes | Technology Assessment | Health/Medicine | North America