Resources Repository
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Lesson/ModuleWeb Portal, Teaching Resource 2016DNA Evidence: Case Study in Probabilities
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case …
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case in which federal courts at every level discerned “inaccuracies” in the testimony of a leading expert about probabilities associated with the DNA evidence. By embedding these legal materials in background explanations, critical questions, and short problems, the module supports self-study and class discussions that together can elucidate key principles in scientific reasoning and quantitative analysis and that can help students…
Risk Analysis | Global | Test Performance | Probability/Bayes | Injuries/Accidents | Government/Law | Health/Medicine | Science/Technology | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Resource PackPublication, Teaching Resource 2023Resource Pack: Diagnostic Tests, Bayes, and COVID-19
This resource pack provides a curated set of articles, perspectives, and interactives about diagnostic testing …
This resource pack provides a curated set of articles, perspectives, and interactives about diagnostic testing for COVID-19. The pack provides materials that will be particularly useful for educators who are teaching diagnostic test performance, value of information, and probability revision using Bayes’ theorem. The majority of papers focus on PCR or rapid antigen testing on samples obtained from the respiratory tract by nasopharyngeal swab. The mechanism of false negative results (e.g., timing of sample collection…
Global | Test Performance | Probability/Bayes | Value of Information | Decision Analysis | Health/Medicine | Science/Technology | High School | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Graphics/Visualization | Quantitative Literacy -
ArticlePublication 2020Perceptions of COVID-19 around the World
This study evaluates public risk perception of COVID-19 around the world in ten countries across …
This study evaluates public risk perception of COVID-19 around the world in ten countries across Europe, America, and Asia. They found that significant predictors of risk perception included personal experience with the virus, individualistic and prosocial values, hearing about the virus from friends and family, trust in government, science, and medical professionals, personal knowledge of government strategy, and personal and collective efficacy. Although there was substantial variability across cultures, individualistic worldviews, personal experience, prosocial values,…
Risk Analysis | Global | Decision Psychology | Preferences/Values | Infectious Diseases | Culture/Society | Health/Medicine -
EditorialPublication 2020Waiting for Certainty on COVID-19 Antibody Tests — At What Cost?
This perspective anticipates the availability of serologic antibody testing and considers its potential usefulness in mitigation …
This perspective anticipates the availability of serologic antibody testing and considers its potential usefulness in mitigation policy to reduce COVID-19 transmission. For example: Could we screen for serologic antibodies as a proxy for possible immunity and identify people who could return to the workplace with less severe mitigation measures? The authors acknowledge the uncertainties raised by many policy actors, including the WHO, such as, "Do antibodies confer immunity and, if so, for how long? How accurate is…
Global | Test Performance | Probability/Bayes | Technology Assessment | Infectious Diseases | Health Systems | Policy/Regulation | Government/Law | Health/Medicine | North America -
ArticlePublication 2020Interpreting COVID-19 Test Results: A Bayesian Approach
This article considers the following question with respect to interpreting the results of polymerase chain reaction …
This article considers the following question with respect to interpreting the results of polymerase chain reaction (PCR) assays from nasal and pharyngeal swabs for COVID-19 to inform clinical decision making: "While a positive result in an acutely ill patient is straightforward, how should physicians interpret negative tests in patients with suspected COVID-19 infection?" Using an assumption of near-perfect specificity of PCR assays for COVID-19, the authors acknowledge the uncertainty of test sensitivity. They consider two clinical scenarios…
Global | Test Performance | Probability/Bayes | Infectious Diseases | Health/Medicine | Science/Technology -
Online LearningMultimedia, Teaching Resource 2024Cochrane Interactive Learning
Cochrane Interactive Learning provides over 10 hours of self-directed learning on the complete systematic review …
Cochrane Interactive Learning provides over 10 hours of self-directed learning on the complete systematic review process for both new and experienced authors of systematic reviews following Cochrane methodology. It is useful for both introductory-level learners and more experienced learners who want to refresh and update their knowledge. Trainers may use it for blended learning, combining the online modules as an introduction to more advanced learning in a face-to-face setting. Cochrane Interactive Learning consists of nine modules, each…
Global | Test Performance | Evidence Synthesis | Technology Assessment | Health/Medicine | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Policy Translation | Quantitative Literacy -
ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Risk Analysis | Global | Dynamic Transmission | Decision Analysis | Infectious Diseases | Health Systems | Policy/Regulation | Government/Law | Health/Medicine | Science/Technology -
ArticlePublication 2017Cost-Effectiveness of Testing and Treatment for Latent TB
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve …
Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve TB elimination in the United States. This analysis estimated health outcomes, costs, and cost-effectiveness of LTBI testing and treatment among non-US born residents with and without medical comorbidities (e.g., diabetes, HIV infection, and end-stage renal disease). A decision analytic tree and Markov cohort simulation model was used to compare the following strategies: no testing, tuberculin skin test (TST), interferon gamma release assay…
Global | Test Performance | State-Transition | Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Economics/Finance | Health/Medicine | North America -
Resource PortalWeb Portal, Teaching Resource 2024Cochrane
Cochrane produces reviews which study all of the best available evidence generated through research and …
Cochrane produces reviews which study all of the best available evidence generated through research and make it easier to inform decisions about health. In addition to the production and dissemination of systematic reviews, housed in the Cochrane Library, they provide a host of resources such as handbooks and guidelines, interactive learning modules, web casts and other educational public goods. Cochrane is a not-for profit organisation with collaborators from more than 120 countries working together to produce…
Global | Test Performance | Evidence Synthesis | Technology Assessment | Health Systems | Health/Medicine