Resources Repository
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ArticlePublication 2022Comparison of Home Antigen Testing With RT-PCR and Viral Culture During the Course of SARS-CoV-2 Infection
As the availability of at-home self-collected antigen tests for SARS-CoV-2 increases, understanding their efficacy is …
As the availability of at-home self-collected antigen tests for SARS-CoV-2 increases, understanding their efficacy is crucial. A study in San Diego and Denver between January and May 2021 assessed the reliability of these tests against standard RT-PCR tests and viral cultures. Of the 225 participants with confirmed infections, the antigen test sensitivity was found to be 50% during the infectious period, 64% against the same-day RT-PCR, and 84% against the same-day cultures. Sensitivity was highest…
Science/Technology | Clinical Care | Test Performance | Infectious Diseases | Culture/Society | Health/Medicine -
ReviewPublication 2022Diagnostics for COVID-19: Moving from Pandemic Response to Control
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 …
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 infections. Each test type remains vital as we shift from responding to controlling the pandemic. Molecular tests, like PCR, are highly precise in identifying viral RNA and are endorsed by the WHO for confirming cases and guiding public health actions. Antigen rapid tests spot viral proteins and, while less accurate than molecular tests, are quicker, more affordable, simpler, and can…
Science/Technology | Clinical Care | Test Performance | Infectious Diseases | Health Systems | Health/Medicine -
ArticlePublication 2021Individual and Social Determinants of COVID-19 Vaccine Uptake
This article examined the individual, communication and social determinants associated with COVID-19 vaccine uptake using …
This article examined the individual, communication and social determinants associated with COVID-19 vaccine uptake using national survey data collected before vaccines were available in the U.S. Of note, individuals under the federal poverty level and racial and ethnic minorities were oversampled. Outcomes included the likelihood of vaccinating self and dependents (e.g., children). Independent variables included perceptions of risk, exposure to different media for COVID-19 news, political party identification, confidence in scientists and social determinants of…
Science/Technology | Clinical Care | Health Outcomes | Evidence Synthesis | Infectious Diseases | Social Determinants | Policy/Regulation | Culture/Society | Health/Medicine | North America -
ReportPublication 2021What the American Public Thinks About Vaccines and How Framing Can Help
This paper explores the question of public understandings, beliefs, and attitudes about vaccination in general, …
This paper explores the question of public understandings, beliefs, and attitudes about vaccination in general, and childhood vaccination more specifically. The authors provide an overview of the existing literature on public thinking about vaccination and on effective communication strategies and interventions that have been either suggested or empirically tested. This description was extracted from the publication abstract.
Science/Technology | Child/Nutrition | Preferences/Values | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | North America -
ArticlePublication 2021Measuring the Impact of COVID-19 Vaccine Misinformation on Vaccination Intent in the U.K. and U.S.
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight …
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight the COVID-19 pandemic, but high uptake achievement will be a challenge and may be impeded by online misinformation. This article is a randomized controlled trial in the U.K. and the U.S. with the objective to quantify how exposure to online misinformation around COVID-19 vaccines affects intent to vaccinate to protect oneself or others. The authors report that in both countries…
Science/Technology | Child/Nutrition | Decision Psychology | Preferences/Values | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | North America | Europe -
ArticlePublication 2017Misinformation Lingers in Memory: Failure of Three Pro-Vaccination Strategies
People's inability to update their memories in light of corrective information may have important public …
People's inability to update their memories in light of corrective information may have important public health consequences, as in the case of vaccination choice. The authors compare three potentially effective strategies in vaccine promotion: (1) one contrasting myths vs. facts, (2) one employing fact and icon boxes, and (3) one showing images of non-vaccinated sick children. Beliefs in the autism/vaccines link and in vaccines side effects, along with intention to vaccinate a future child, were…
Science/Technology | Child/Nutrition | Decision Psychology | Preferences/Values | Infectious Diseases | Culture/Society | Government/Law | Health/Medicine | North America -
ArticlePublication 2019Countering Misinformation with Lessons from Public Health
The internet is often praised as a tool for freedom of speech, democracy, and truth. …
The internet is often praised as a tool for freedom of speech, democracy, and truth. However, the internet increasingly has become polluted by misinformation – the inadvertent spread of misleading and false information – and disinformation – the deliberate and coordinated spread of misleading and false information. Individuals online knowingly and unknowingly spread dangerous rumors and propaganda at an alarming rate, which can mislead or manipulate the worldview of those who encounter it. False information…
Science/Technology | Child/Nutrition | Decision Psychology | Preferences/Values | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | Global | North America -
ToolInteractive 2020COVID-19 Antibody Tests: Calculator for Interpreting Test Results
Antibody testing can determine previous exposure to SARS-CoV-2 virus. This interactive calculator, linked to the article …
Antibody testing can determine previous exposure to SARS-CoV-2 virus. This interactive calculator, linked to the article below* on antibody testing for SARS-CoV-2 virus, allows users to vary the prior probability of infection, the sensitivity of SARS-CoV-2 antibody testing, and the specificity of SARS-CoV-2 antibody testing. Key points made in the article accompanying the interactive include: (1) antibody testing is likely to be most useful 2 weeks after infection, (2) sensitivity and specificity will vary over time and…
Science/Technology | Clinical Care | Probability/Bayes | Test Performance | Technology Assessment | Infectious Diseases | Health/Medicine -
Tools/ModelsInteractive, Teaching Resource 2020Interactive Graphic: Interpreting a COVID-19 Test Result
Currently, the most common diagnostic test for COVID-19 relies on reverse transcriptase polymerase chain reaction …
Currently, the most common diagnostic test for COVID-19 relies on reverse transcriptase polymerase chain reaction (RT-PCR), and most often uses samples obtained from the respiratory tract by nasopharyngeal swab. This interactive graphic demonstrates the influence of the prior probability of COVID-19, the test sensitivity (i.e., the probability of a positive test conditional on disease presence), and the test specificity (i.e., the probability of a negative test conditional on disease absence) on the post-test probability of…
Science/Technology | Clinical Care | Probability/Bayes | Test Performance | Infectious Diseases | Health/Medicine | High School | College | Graduate | Doctoral | Professional | Graphics/Visualization | Quantitative Literacy