Resources Repository
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ArticlePublication 2019Spatial Distribution and Characteristics of HIV
This article, published in Tropical Medicine & International Health, aims to identify the spatial and …
This article, published in Tropical Medicine & International Health, aims to identify the spatial and temporal trends, and epidemiologic correlates, of HIV clusters in Ethiopia. The authors use biomarker and survey data from the 2005, 2011, and 2016 Ethiopia Demographic and Health Surveys (DHS), and the spatial-temporal distribution of HIV is estimated using the Kulldorff spatial scan statistic, a likelihood-based method for determining clustering. The study results indicate that in Ethiopia, geographic HIV clusters are…
Mathematical Models | Health/Medicine | Infectious Diseases | Health Systems | Sub-Saharan Africa -
ArticlePublication 2019Cost-Effectiveness of Clinic, Home, or Ambulatory Blood Pressure Measurement for Hypertension Diagnosis
This study compared three methods of blood pressure (BP) measurement for diagnosing hypertension in primary …
This study compared three methods of blood pressure (BP) measurement for diagnosing hypertension in primary care settings, accounting for the possibility of false-positive (white-coat hypertension) and false-negative (masked hypertension) clinic measurements. Outcomes included quality-adjusted life years (QALYs) and lifetime costs associated with clinic BP measurement, home BP monitoring, and ambulatory blood pressure monitoring (ABPM) under two scenarios: positive and negative initial screening. Data were from published literature, public data sources, and expert input. In the…
Mathematical Models | Health/Medicine | Cost-Effectiveness Analysis | Chronic Disease/Risk | Clinical Care | North America -
ArticlePublication 2019Systematic Review of Economic Evaluations of Vaccination Strategies Against Tuberculosis
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis, but its effectiveness is limited …
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis, but its effectiveness is limited and varies by age, so a valid cost-effectiveness study is needed to assist decision-makers in the implementation of cost-effective strategies for BCG vaccination. Using the Quality of Health Economic Studies (QHES) instrument, the authors assessed the quality of published studies involving economic evaluations of BCG vaccination strategies in a variety of regions, target populations, and vaccine types. Most of the…
Mathematical Models | Health/Medicine | Evidence Synthesis | Cost-Effectiveness Analysis | Infectious Diseases | Global -
Lesson/ModuleVideo, Teaching Resource 2018Sensitivity Analyses
This video is intended to provide an introduction to the use of sensitivity analyses to …
This video is intended to provide an introduction to the use of sensitivity analyses to test how uncertainty impacts model predicted results. Uncertainty from point estimates used for model inputs is discussed as is testing using deterministic and probabilistic sensitivity analyses. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of Veterans Affairs Health Services Research and Development group focused on cost-effectiveness analysis and…
Mathematical Models | Health/Medicine | Decision Analysis | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Evidence Synthesis Part II: Quantitative Pooling
This video is intended to provide researchers with an introduction to the second part of conducting …
This video is intended to provide researchers with an introduction to the second part of conducting a meta-analysis: quantitatively pooling. The goal of this meta-analysis is to synthesize multiple published estimates from parameters of interest (such as disease-related mortality or the efficacy of a treatment) into a single input for use in a decision model. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of…
Mathematical Models | Health/Medicine | Evidence Synthesis | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Evidence Synthesis Part I: Systematic Literature Review
This video is intended to provide researchers with an introduction to the first part of …
This video is intended to provide researchers with an introduction to the first part of conducting a meta-analysis: a systematic literature review. The goal of this meta-analysis is to synthesize multiple published estimates from parameters of interest (such as disease-related mortality or the efficacy of a treatment) into a single input for use in a decision model. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the…
Mathematical Models | Health/Medicine | Evidence Synthesis | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Estimating Transition Probabilities for a Model
This video is intended to provide a discussion on various methods for deriving probabilities that are …
This video is intended to provide a discussion on various methods for deriving probabilities that are needed for decision models. Presented are the concepts of literature based Odds Ratios and Relative Risks, which need to be transformed into probabilities, how to deal with probability estimates from time frames not relevant to the model in question, and how to derive probabilities from published summary statistics. This lecture is aimed at the researcher who is interested in operationalizing…
Mathematical Models | Health/Medicine | Probability/Bayes | Evidence Synthesis | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018An Overview of Decision Analysis
This video is intended to provide high-level overview of the field of decision analysis and …
This video is intended to provide high-level overview of the field of decision analysis and presents topics that include: why engage in decision analysis; what are the differences between cost-effectiveness analysis, cost-utility analysis, cost-benefit analysis, and budget impact analysis; and different ways to conduct a decision analysis – such as modeling or measuring alongside a clinical trial. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the…
Mathematical Models | Health/Medicine | Decision Analysis | Cost-Effectiveness Analysis | Health Systems | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ReportPublication 2013Decision and Simulation Modeling Alongside Systematic Reviews
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks …
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The chapter discusses the role of decision analysis and decision-analytic models in health care, specifically within the context of the current emphasis on evidence-based medicine and the proliferation of systematic reviews. It describes the types of model available…
State-Transition | Health/Medicine | Evidence Synthesis | Dynamic Transmission | Microsimulation | Dynamic Simulation | Health Systems | Clinical Care