Resources Repository
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ReviewPublication 2022Diagnostics for COVID-19: Moving from Pandemic Response to Control
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 …
Diagnostics are essential in managing the COVID-19 pandemic, with three primary methods for detecting SARS-CoV-2 infections. Each test type remains vital as we shift from responding to controlling the pandemic. Molecular tests, like PCR, are highly precise in identifying viral RNA and are endorsed by the WHO for confirming cases and guiding public health actions. Antigen rapid tests spot viral proteins and, while less accurate than molecular tests, are quicker, more affordable, simpler, and can…
Test Performance | Infectious Diseases | Health Systems | Clinical Care | Health/Medicine | Science/Technology -
ReviewPublication 2022Systematic Review of Economic Evaluations of COVID-19 Interventions: Non-Health Impacts and Distributional Issues
The authors conducted a systematic review of economic evaluations of COVID-19 interventions and assessed whether …
The authors conducted a systematic review of economic evaluations of COVID-19 interventions and assessed whether they incorporated non-health impacts and distributional concerns. Among the 70 articles included, more than half (56%) included at least one non-health impact, although only 21% incorporated non-economic consequences. Only 17% examined subgroups of interest. The median ICER for the entire sample was $67,000/quality-adjusted life-year (QALY) (interquartile range [IQR] $9000-$893,000/QALY). Interventions including a pharmaceutical component yielded a median ICER of $93,000/QALY (IQR…
Evidence Synthesis | Cost-Effectiveness Analysis | Infectious Diseases | Social Determinants | Culture/Society | Economics/Finance | Health/Medicine | North America -
ReviewPublication 2021Users' Guide to Medical Decision Analysis
The article emphasizes the significance of decision analysis in aiding clinicians to make evidence-based choices …
The article emphasizes the significance of decision analysis in aiding clinicians to make evidence-based choices between testing and treatment strategies. While clinicians may not conduct decision analyses themselves, they often rely on publications or guidelines derived from them. The review outlines the structure of a decision tree and equips clinicians with the skills to critically evaluate decision analyses and implement their findings in medical decision-making. It highlights two critical judgments clinicians can make: first, assessing…
Decision Analysis | Clinical Care | Health/Medicine -
OrganizationPublication 2024Based on Science
Since President Lincoln signed a congressional charter forming the National Academy of Sciences in 1863, …
Since President Lincoln signed a congressional charter forming the National Academy of Sciences in 1863, the National Academies have served the nation by drawing on the knowledge of the country’s top experts to deliver nonpartisan, objective advice on scientific matters. Based On Science uses the community of experts to provide the most up-to-date, evidence-based information about science and health questions that affect the decisions we make each day. This description was extracted from the Based…
Evidence Synthesis | Climate/Environment | Culture/Society | Energy/Engineering | Education/Labor | Health/Medicine | Science/Technology | North America -
ReviewPublication 2020Public Health and Online Misinformation: Challenges and Recommendations
The internet has become a popular resource to learn about health and to investigate one's …
The internet has become a popular resource to learn about health and to investigate one's own health condition. However, given the large amount of inaccurate information online, people can easily become misinformed. Individuals have always obtained information from outside the formal health care system, so how has the internet changed people's engagement with health information? This review explores how individuals interact with health misinformation online, whether it be through search, user-generated content, or mobile apps.…
Evidence Synthesis | Social Determinants | Health Systems | Culture/Society | Health/Medicine | North America -
ReviewPublication 2018Equity Considerations in CEA: Rotavirus Vaccine in LMIC's
The authors used a systematic review of the literature to identify economic evaluations of rotavirus …
The authors used a systematic review of the literature to identify economic evaluations of rotavirus vaccine in LMICs and assess the extent to which equity was considered in the objectives, analysis, and results. They used equity-related indicators provided in the Guidance on Priority Setting in Health Care (GPS-Health) checklist criteria resulting in 18 unique indicators tracked. The authors found that some articles incorporated the indicators in their model inputs (20%) while the majority (80%) presented…
Evidence Synthesis | Cost-Effectiveness Analysis | Infectious Diseases | Social Determinants | Health/Medicine | Global -
ReviewPublication 2018Setting Health Sector Priorities: A Brief Overview of Ethiopia's Experience
Based on Ethiopia’s commitment to attain universal health coverage by 2035, the authors use the …
Based on Ethiopia’s commitment to attain universal health coverage by 2035, the authors use the current national strategies including the national essential health service package in Ethiopia as a springboard to explore the criteria and processes Ethiopia uses to set the existing national health sector priorities. Addition the authors highlight the critical need to strengthen country-led efforts and investments in human capital in developing country contexts.
Evidence Synthesis | Priority Setting/Ethics | Health Systems | Policy/Regulation | Health/Medicine | Sub-Saharan Africa -
OrganizationWeb Portal 2024Council of Economic Advisers
The Council of Economic Advisers is an agency within the Executive Office of the President …
The Council of Economic Advisers is an agency within the Executive Office of the President and is charged with offering the President objective economic advice on the formulation of both domestic and international economic policy. The Council bases its recommendations and analysis on economic research and empirical evidence, using the best data available to support the President in setting our nation's economic policy. Learn about recent news and reports.
Evidence Synthesis | Risk Analysis | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Policy/Regulation | Economics/Finance | Government/Law | North America -
ReviewPublication 2017Validation and Calibration of Structural Models that Combine Information from Multiple Sources
This is a review of calibration and validation methods in mathematical modeling. Such models that …
This is a review of calibration and validation methods in mathematical modeling. Such models that attempt to capture structural relationships between their components and combine information from multiple sources are increasingly used in medicine. The authors provide an overview of methods for model validation and calibration and survey studies comparing alternative approaches. Model validation entails a confrontation of models with data, background knowledge, and other models, and can inform judgments about model credibility. Calibration involves…
Mathematical Models | Calibration/Validation | Health/Medicine