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Resources Repository
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ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Risk Analysis | Decision Analysis | Dynamic Transmission | Government/Law | Science/Technology | Global | Infectious Diseases | Health Systems | Policy/Regulation | Health/Medicine -
BookPublication 2017What's In, What's Out: Designing Benefits for Universal Health Coverage
Many low- and middle-income countries now aspire to universal health coverage, where governments ensure that …
Many low- and middle-income countries now aspire to universal health coverage, where governments ensure that all people have access to the quality health services they need without risk of impoverishment. But for universal health coverage to become reality, the health services offered must be consistent with the funds available-and this implies tough everyday choices for policymakers. This publication argues that the creation of an explicit health benefits plan-a defined list of services that are and are…
Priority Setting/Ethics | Technology Assessment | Cost-Effectiveness Analysis | Government/Law | Science/Technology | Global | Health Outcomes | Evidence Synthesis | Health Systems | Policy/Regulation | Economics/Finance | Health/Medicine -
ReviewPublication 2008Cost-Effectiveness of Vaccination: Review of Modelling Approaches
This review examines the modelling approaches used in cost-effectiveness analyses (CEAs) of vaccination programs. After …
This review examines the modelling approaches used in cost-effectiveness analyses (CEAs) of vaccination programs. After overviewing the key attributes of models used in CEAs, a framework for categorizing theoretical models is presented. Categories are based on three main attributes: static/dynamic; stochastic/deterministic; and aggregate/individual based.
Dynamic Simulation | Microsimulation | Mathematical Models | Cost-Effectiveness Analysis | Dynamic Transmission | State-Transition | Science/Technology | Global | Infectious Diseases | Health/Medicine -
ReviewPublication 2016Decision Support for Infectious Disease Control
This report from RAND reviews decision-support tools, including models and nonmodeling approaches, that are relevant to …
This report from RAND reviews decision-support tools, including models and nonmodeling approaches, that are relevant to infectious disease prevention, detection, and response and aligns these tools with real-world policy questions that the tools can help address. This overview is designed to help modelers and other technical experts understand the questions that policymakers will raise and the decisions they must make. The report also presents policymakers with the capabilities and limitations of the different tools that may…
Dynamic Simulation | Microsimulation | Mathematical Models | Dynamic Transmission | State-Transition | Government/Law | Global | Infectious Diseases | Global Governance | Health/Medicine | Military/Defense -
BookPublication 2014Decision Making in Health and Medicine: Integrating Evidence and Values
Decision making in health care involves consideration of a complex set of diagnostic, therapeutic and …
Decision making in health care involves consideration of a complex set of diagnostic, therapeutic and prognostic uncertainties. Medical therapies have side effects, surgical interventions may lead to complications, and diagnostic tests can produce misleading results. Furthermore, patient values and service costs must be considered. Decisions in clinical and health policy require careful weighing of risks and benefits and are commonly a trade-off of competing objectives: maximizing quality of life vs maximizing life expectancy vs minimizing…
Preferences/Values | Mathematical Models | Test Performance | Cost-Effectiveness Analysis | Decision Analysis | Government/Law | Global | Probability/Bayes | Costing Methods | Health Outcomes | Value of Information | Health Systems | Economics/Finance | Health/Medicine | North America | Europe | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
BookPublication 2010Problem Solving, Decision Making, and Professional Judgment
This book includes material drawn from statistics, decision science, social and cognitive psychology, the judgment …
This book includes material drawn from statistics, decision science, social and cognitive psychology, the judgment and decision making literature, and behavioral economics. It combines quantitative approaches to empirical analysis and decision making (i.e., statistics and decision science) with the psychological literature illustrating the systematic errors of the intuitive decision maker.
Priority Setting/Ethics | Preferences/Values | Test Performance | Cost-Effectiveness Analysis | Decision Analysis | Government/Law | Global | Probability/Bayes | Value of Information | Policy/Regulation | Health/Medicine | North America -
ArticlePublication 2017When Cost-Effective Interventions Are Unaffordable
Many health interventions deemed cost-effective are not affordable. Despite the importance of affordability to policymakers, …
Many health interventions deemed cost-effective are not affordable. Despite the importance of affordability to policymakers, little of the cost-effectiveness literature in global health addresses this issue. Budget impact analysis (BIA) describes an intervention's short-term costs and savings from the payer's perspective. This paper assesses the current use of budget impact analysis (BIA) and cost-effectiveness analysis (CEA) in health economic assessments conducted for low- and middle-income countries (LMICs). The authors recommend steps researchers and policymakers can…
Priority Setting/Ethics | Cost-Effectiveness Analysis | Government/Law | Science/Technology | Global | Costing Methods | Infectious Diseases | Chronic Disease/Risk | Health Systems | Economics/Finance | Health/Medicine -
Tools/ModelsPublication, Teaching Resource 2017Publicly Available Software Tools for Decision-Makers During an Emergent Epidemic
Epidemics and emerging infectious diseases are becoming an increasing threat to global populations-challenging public health …
Epidemics and emerging infectious diseases are becoming an increasing threat to global populations-challenging public health practitioners, decision makers and researchers to plan, prepare, identify and respond to outbreaks in near real-timeframes. The aim of this research is to evaluate the range of public domain and freely available software epidemic modelling tools. Twenty freely utilizable software tools underwent assessment of software usability, utility and key functionalities. Stochastic and agent based tools were found to be highly…
Dynamic Simulation | Mathematical Models | Dynamic Transmission | Science/Technology | Global | Infectious Diseases | Health Systems | Climate/Environment | Health/Medicine | Graduate | Doctoral | Professional | Quantitative Literacy -
ArticlePublication 2016Accounting for Technical, Ethical, and Political Factors in Priority Setting
This article investigates two cases of priority setting to explore how, in addition to technical …
This article investigates two cases of priority setting to explore how, in addition to technical considerations, ethical and political factors shape the allocation of health resources. First, they discuss how Thai authorities adjudicated a coverage decision for HLA-B*1502 screening, which meets the national cost-effectiveness threshold for only some of the conditions it can detect. Second, they consider England’s Cancer Drugs Fund to investigate the interplay of technical decision making and political reality. The findings suggest four concluding…
Priority Setting/Ethics | Cost-Effectiveness Analysis | Government/Law | Science/Technology | Global | Chronic Disease/Risk | Health Systems | Policy/Regulation | Climate/Environment | Health/Medicine | Europe