- decision psychology
- priority setting/ethics
- methods and metrics
- costing methods
- health outcomes
- evidence synthesis
- test performance
- value of information
- models and tools
- mathematical models
- state-transition
- dynamic transmission
- microsimulation
- calibration/validation
- decision analysis
- operations research
Resources Repository
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ReportPublication 2014Redirecting Innovation in U.S. Health Care
This report from RAND Health explores methods of reducing health care spending and developing medical …
This report from RAND Health explores methods of reducing health care spending and developing medical products that provide cost value with health benefits. It summarizes literature and explores case studies to provide policy recommendations to meet these goals. It identifies a wide range of factors that affect the costs, risks, and rewards of medical product invention. Some of these features include treatment creep, the medical arms race, costs and risks of FDA approval, limited reward…
Evidence Synthesis | Costing Methods | Health Outcomes | Health Systems | Policy/Regulation | Economics/Finance | Government/Law | Health/Medicine | Science/Technology | North America -
ReviewPublication 2014Markov Modeling & Discrete Event Simulation in Health Care: Systematic Comparison
This review assesses whether the use of Markov modeling (MM) or discrete event simulation (DES) …
This review assesses whether the use of Markov modeling (MM) or discrete event simulation (DES) for cost-effectiveness analysis (CEA) may alter healthcare resource allocation decisions. A systematic literature search and review of empirical and non-empirical studies comparing MM and DES techniques used in the CEA of healthcare technologies was conducted. The primary advantages described for DES over MM were the ability to model queuing for limited resources, capture individual patient histories, accommodate complexity and uncertainty,…
Microsimulation | Mathematical Models | State-Transition | Health Systems | Clinical Care | Health/Medicine -
ReviewPublication 2011Dynamic Microsimulation Models for Health Outcomes: A Review
This review article presents an overview of microsimulation modeling, focusing on the development and application …
This review article presents an overview of microsimulation modeling, focusing on the development and application of these models for health policy questions. Microsimulation models for health outcomes simulate individual event histories associated with key components of a disease process; these simulated life histories can be aggregated to estimate population-level effects of treatment on disease outcomes and the comparative effectiveness of treatments. The authors argue that methodological improvements in modeling approaches have been slowed by the…
Microsimulation | Calibration/Validation | Health Outcomes | Health/Medicine -
ReviewPublication 2001Modeling for Health Care and Other Policy Decisions: Uses, Roles and Validity
This is a review article of the role of modeling approaches to guide decision making …
This is a review article of the role of modeling approaches to guide decision making in health care and other domains. The role of models to support recommendations on the cost-effective use of medical technologies and pharmaceuticals is controversial. At the heart of the controversy is the degree to which experimental or other empirical evidence should be required prior to model use. The authors argue that the controversy stems in part from a misconception that…
Evidence Synthesis | Priority Setting/Ethics | Mathematical Models | Technology Assessment | Environmental Health | Health Systems | Policy/Regulation | Business/Industry | Climate/Environment | Economics/Finance | Energy/Engineering | Government/Law | Health/Medicine | North America -
ReportPublication 2023Roadmap for Increasing the Usefulness and Impact of Patient-Preference Studies in Decision Making in Health
This ISPOR Task Force report examines the integration of patient preferences into healthcare decision-making, emphasizing …
This ISPOR Task Force report examines the integration of patient preferences into healthcare decision-making, emphasizing the growing significance of both qualitative and quantitative methods for studying these preferences. The report synthesizes current best practices to enhance the utility and impact of patient-preference studies. The methods involved reviewing existing literature and practices to construct the ISPOR Roadmap for Patient Preferences in Decision Making. This roadmap encourages collaboration among researchers, decision-makers, patients, patient groups, and other stakeholders.…
Evidence Synthesis | Health Outcomes | Preferences/Values | Health/Medicine -
ReviewPublication 2023Systematic Review of Cost-Effectiveness Studies of Newer Non-Insulin Antidiabetic Drugs: Trends in Decision-Analytical Models for Modelling of Type 2 Diabetes Mellitus
This systematic review analyzed cost-effectiveness analyses (CEAs) using decision-analytical modeling (DAM) to compare non-insulin antidiabetic …
This systematic review analyzed cost-effectiveness analyses (CEAs) using decision-analytical modeling (DAM) to compare non-insulin antidiabetic drugs (NIADs) within glucagon-like peptide-1 (GLP1) receptor agonists, sodium-glucose cotransporter-2 (SGLT2) inhibitors, or dipeptidyl peptidase-4 (DPP4) inhibitors for treating type 2 diabetes mellitus (T2DM). The study focused on economic results and underlying methodological choices. Methods included searching PubMed, Embase, and Econlit databases from January 1, 2018, to November 15, 2022. Two reviewers screened titles, abstracts, and full texts for relevance…
Evidence Synthesis | Mathematical Models | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health/Medicine | Europe -
ReviewPublication 2023How Values Are Discussed, Reflected Upon, and Acted on by Patients and Family Caregivers in the Context of Heart Failure: Scoping Review
The study examines how values influence decision-making and coping among heart failure (HF) patients and …
The study examines how values influence decision-making and coping among heart failure (HF) patients and their family caregivers (FCGs). Through a scoping review of 16 empirical studies, patient values were found to influence self-care behaviors and left ventricular assist device (LVAD) implantation decisions, with variations in prioritization over time and contexts. Conflicts between prioritized values and recommended self-care activities led to modifications in behavior. Patient survival emerged as a top value during cardiac device decisions.…
Evidence Synthesis | Decision Psychology | Preferences/Values | Chronic Disease/Risk | Health/Medicine -
ReviewPublication 2021Review of Web-Based Tools for Value-of-Information Analysis
Value-of-information analysis (VOI) is an analytic approach used to inform research priorities, guide clinical trial …
Value-of-information analysis (VOI) is an analytic approach used to inform research priorities, guide clinical trial design, and provide information for decisions about reimbursement. The authors review existing web-based tools to facilitate VOI calculations. These include Sheffield Accelerated Value of Information (SAVI), the web interface to the BCEA (Bayesian Cost-Effectiveness Analysis) R package (BCEAweb), Rapid Assessment of Need for Evidence (RANE), and Value of Information for Cardiovascular Trials and Other Comparative Research (VICTOR).
Priority Setting/Ethics | Value of Information | Decision Theory | Cost-Effectiveness Analysis | Economics/Finance | Health/Medicine -
ReportPublication 2017Communicating Science Effectively: A Research Agenda
Science and technology are embedded in virtually every aspect of modern life. As a result, …
Science and technology are embedded in virtually every aspect of modern life. As a result, people face an increasing need to integrate information from science with their personal values and other considerations as they make important life decisions about medical care, the safety of foods, what to do about climate change, and many other issues. Communicating science effectively, however, is a complex task and an acquired skill. Moreover, the approaches to communicating science that will…
Priority Setting/Ethics | Decision Psychology | Preferences/Values | Social Determinants | Climate/Environment | Culture/Society | Energy/Engineering | Education/Labor | Health/Medicine | Science/Technology | North America