Resources Repository
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Resource PackWeb Portal, Teaching Resource 2023Resource Pack: Cost-Effectiveness of Screening and Treatment for Hypertension
Hypertension is a relevant example for teaching clinical decision making, diagnostic test performance, positivity criterion, …
Hypertension is a relevant example for teaching clinical decision making, diagnostic test performance, positivity criterion, and cost-effectiveness analysis. This resource pack provides examples of decision analyses and cost-effectiveness analyses for the management and treatment of hypertension, with a predominant focus on the U.S. Analyses are included that predate the 2017 American College of Cardiology/American Heart Association Clinical Practice Guidelines, along with more recent examples that followed release of the guidelines. Resources are also included that…
Decision Analysis | Clinical Care | Preferences/Values | Test Performance | Cost-Effectiveness Analysis | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Science/Technology | North America | Europe | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Policy Translation | Quantitative Literacy -
Tutorial/PrimerPublication, Teaching Resource 2024Tutorial: Introduction to Programming Decision Trees
This self-directed tutorial walks through the development of a decision tree using Amua to evaluate …
This self-directed tutorial walks through the development of a decision tree using Amua to evaluate three initial management strategies for ductal carcinoma in situ (DCIS) based on a published analysis: Soeteman DI, Stout NK, Ozanne EM et al. Modeling the Effectiveness of Initial Management Strategies for Ductal Carcinoma in Situ. J Natl Cancer Inst 2013; 105 (11): 774-781. The tutorial describes how to build the model structure, parameterize the model probabilities and outcomes based on…
Decision Analysis | Clinical Care | Mathematical Models | Health/Medicine | Graduate | Doctoral | Professional -
ArticlePublication 2023Achieving the Cancer Moonshot Goal
The Cancer Moonshot seeks to reduce age-standardized cancer mortality rates by at least 50% over …
The Cancer Moonshot seeks to reduce age-standardized cancer mortality rates by at least 50% over the next 25 years. This article estimates trends in U.S. cancer mortality for all cancers and the six leading types and reviews opportunities to prevent, detect, and treat these common cancers.
Priority Setting/Ethics | Clinical Care | Mathematical Models | Health Systems | Health/Medicine | North America -
ArticlePublication 2019Global Childhood Cancer Survival Estimates and Priority-Setting: A Simulation-Based Analysis
This modelling study provides estimates of global childhood cancer survival, accounting for the impact of …
This modelling study provides estimates of global childhood cancer survival, accounting for the impact of multiple factors that affect cancer outcomes in children. The authors developed a microsimulation model to simulate childhood cancer survival for 200 countries/territories, accounting for clinical and epidemiologic factors, including country-specific treatment variables, such as availability of chemotherapy, radiation, and surgery, and calibrated the model to empirical data from the CONCORD-2 and CONCORD-3 studies using an Approximate Bayesian Computation approach. The…
Priority Setting/Ethics | Clinical Care | Health Outcomes | Microsimulation | Child/Nutrition | Chronic Disease/Risk | Global -
ArticlePublication 2020Incorporating Perspective into Clinical Decisions
Part of a six-part series of articles on clinical decision making, in this article, the …
Part of a six-part series of articles on clinical decision making, in this article, the authors discuss how to incorporate perspective into clinical decisions, explicitly acknowledging that the treating physician is not the only stakeholder in these decisions. The authors use 2 case studies to demonstrate how changes in perspective can alter the clinical decision as well lead to both intended and unintended consequences to the outcomes.
Priority Setting/Ethics | Clinical Care | Preferences/Values | Health Outcomes | Health Systems | Health/Medicine -
ArticlePublication 2020Weighing Evidence to Inform Clinical Decisions
The authors use a clinical example to simulate how treatment discussions can be complicated when new evidence is introduced …
The authors use a clinical example to simulate how treatment discussions can be complicated when new evidence is introduced that conflicts with existing guidelines. Even when evidence is consistent, the authors point out that current guidelines can have interpretations that don't agree with available evidence. They develop a step-wise algorithm to help guide individual clinical decisions even in the absence of general consensus related to appropriate testing and treatment.
Priority Setting/Ethics | Clinical Care | Evidence Synthesis | Health/Medicine -
Resource PortalWeb Portal, Teaching Resource 2021Disease Control Priorities (DCP3)
DCP3 includes a comprehensive review of the efficacy, effectiveness, and cost-effectiveness of priority health interventions …
DCP3 includes a comprehensive review of the efficacy, effectiveness, and cost-effectiveness of priority health interventions with the goal of influencing program design and resource allocation at global and country levels. DCP3 includes nine individual volumes, with the first eight structured around packages of conceptually related interventions, and the ninth providing an overview of main findings. Publicly available resources include journal articles and reports, both DCP3 and non-DCP3 related, as well as presentations, working papers, and book…
Priority Setting/Ethics | Injuries/Accidents | Costing Methods | Evidence Synthesis | Cost-Effectiveness Analysis | Infectious Diseases | Maternal/Reproductive Health | Child/Nutrition | Chronic Disease/Risk | Mental Health | Health Systems | Policy/Regulation | Health/Medicine | Science/Technology | Global | High School | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Policy Translation -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Valuing Individual Health Outcomes
In this teaching pack on Valuing Individual Health Outcomes, students learn how to assign quantitative …
In this teaching pack on Valuing Individual Health Outcomes, students learn how to assign quantitative values to health outcomes at the individual level, including: expected utility theory, the axioms of this theory, distinguishing between preference-based measures of value and health-related quality of life outcomes, measuring utility using the standard gamble, the time trade-off, and the visual analog scale, and understanding the limitations of these measures. Materials include an instructor's note, videos, companion slides, a glossary,…
Decision Analysis | Injuries/Accidents | Preferences/Values | Health Outcomes | Economics/Finance | Health/Medicine | College | Graduate | Doctoral -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Population Health Outcomes
In this teaching pack on Population Health Outcomes, students learn how to describe outcomes at a …
In this teaching pack on Population Health Outcomes, students learn how to describe outcomes at a population level using quality adjusted life years (QALYs), including how to calculate QALYs, the assumptions underlying them, how to derive QALYs using indirect utility measures, and what are some of the ethical criticisms of QALYs. Materials include an instructor’s note, videos, companion slides, a glossary, an annotated bibliography, and sample exercises. Learning Objectives Define Quality-Adjusted Life Years (QALYs)…
Priority Setting/Ethics | Injuries/Accidents | Preferences/Values | Health Outcomes | Health/Medicine | College | Graduate | Doctoral