Resources Repository
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ArticlePublication 2022Conceptualizing Monetary Benchmarks for Health Investments toward Poverty Reduction
Public spending can improve population well-being, for example, by averting or reducing poverty. This article …
Public spending can improve population well-being, for example, by averting or reducing poverty. This article aims to conceptualize monetary benchmarks for health sector investments oriented towards poverty alleviation in low- and lower-middle-income countries. Priority setting in low- and lower-middle-income countries could be informed by health-sector PRBs (poverty reduction benchmarks), in addition to burden of disease and cost-effectiveness considerations. The computed PRBs, expressed in dollars per poverty case averted, can possibly be viewed in a manner…
Evidence Synthesis | Priority Setting/Ethics | Health/Medicine | Global | Health Systems | Social Determinants | Economics/Finance -
ArticlePublication 2016Accounting for Technical, Ethical, and Political Factors in Priority Setting
This article investigates two cases of priority setting to explore how, in addition to technical …
This article investigates two cases of priority setting to explore how, in addition to technical considerations, ethical and political factors shape the allocation of health resources. First, they discuss how Thai authorities adjudicated a coverage decision for HLA-B*1502 screening, which meets the national cost-effectiveness threshold for only some of the conditions it can detect. Second, they consider England’s Cancer Drugs Fund to investigate the interplay of technical decision making and political reality. The findings suggest four concluding…
Priority Setting/Ethics | Health/Medicine | Climate/Environment | Global | Health Systems | Cost-Effectiveness Analysis | Chronic Disease/Risk | Policy/Regulation | Government/Law | Science/Technology | Europe -
ArticlePublication 2023Simulation-Based Estimates and Projections of Global, Regional and Country-Level Maternal Mortality by Cause, 1990-2050
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given …
While progress has been made globally to reduce maternal deaths, measurement remains a challenge given the many causes and frequent underreporting of maternal deaths. The authors developed a structural microsimulation model of Global Maternal Health (GMatH) for 200 countries and territories using demographic, epidemiologic, clinical and health system data synthesized from the medical literature, Civil Registration Vital Statistics systems and Demographic and Health Survey data. The model was calibrated to empirical data from 1990 to…
Evidence Synthesis | Health/Medicine | Global | Health Systems | Health Outcomes | Microsimulation | Calibration/Validation | Maternal/Reproductive Health | Clinical Care -
ArticlePublication 2022Comparative Health Systems Analysis of Differences in Catastrophic Health Expenditure
The growing burden of non-communicable diseases (NCDs) in low- and middle-income countries may have implications …
The growing burden of non-communicable diseases (NCDs) in low- and middle-income countries may have implications for health system performance in the area of financial risk protection, as measured by catastrophic health expenditure (CHE). This article compares non-communicable diseases catastrophic health expenditure to the CHE cases caused by communicable diseases across health systems to examine whether: (1) disease burden and catastrophic health expenditure are linked, (2) Catastrophic health expenditures secondary to NCDs disproportionately affect wealthier households and (3) whether the drivers…
Evidence Synthesis | Health/Medicine | Global | Health Systems | Costing Methods | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Economics/Finance -
ArticlePublication 2018Applications of ECEA Methodology in DCP3
Extended cost-effectiveness analyses (ECEAs) build on cost-effectiveness analyses (CEAs) by assessing consequences in both the …
Extended cost-effectiveness analyses (ECEAs) build on cost-effectiveness analyses (CEAs) by assessing consequences in both the health and non-health domains. The ECEA approach proves novel in that it includes equity and non-health benefits (FRP) in the economic evaluation of health policies, which enables multiple criteria to factor in the decision-making process. More important, the ECEA approach enables the design of benefits packages, such as essential universal health care and the highest-priority package, based on the quantitative…
Priority Setting/Ethics | Health/Medicine | Global | Health Systems | Cost-Effectiveness Analysis | Social Determinants | Global Governance -
ArticlePublication 2018Resource Allocation in Decision Support Frameworks
Multi-criteria decision-making frameworks expand on typical decision analyses (cost-effectiveness and cost-benefit) by explicitly incorporating value …
Multi-criteria decision-making frameworks expand on typical decision analyses (cost-effectiveness and cost-benefit) by explicitly incorporating value tradeoffs from decision makers and summarizing the performance of investment options. This is done across all chosen dimensions of value, based on the weights provided by the decision makers, but comes at a cost. Currently there is no widely accepted method to suggest how to determine a budget constraint using multi-attribute models or to measure willingness to pay for incremental…
Priority Setting/Ethics | Health/Medicine | Global | Health Systems | Benefit-Cost Analysis | Cost-Effectiveness Analysis -
ReviewPublication 2018Incorporating MCDA into HTA: A Focus on Lower Income Settings
The authors present key challenges, both methodological and practical against using multicriteria decision analysis (MCDA) …
The authors present key challenges, both methodological and practical against using multicriteria decision analysis (MCDA) in health technology assessment (HTA) as well as solutions to these challenges. They showcase lessons learned from previous applications of MCDS to HTA, including design, criteria of models, approaches for estimating costs and challenges with various approaches. By showing efforts that have succeeded in overcoming these challenges in lower and middle income-countries, they show how MCDA has the potential to…
Priority Setting/Ethics | Health/Medicine | Global | Health Systems -
ReviewPublication 2018Reflective Multicriteria for Healthcare Decision-Making? The EVIDEM Journey
The authors discuss a framework for mulicriteria decision making for healthcare decision making that was …
The authors discuss a framework for mulicriteria decision making for healthcare decision making that was created and used by the EVIDEM Collaboration between 2006 and 2017. This framework originally incorporated healthcare ethics, evidenced-based medicine, health economics, health technology assessment and multicriteria approaches to decision making. The authors present this modified 10th edition framework, which builds on these by enhancing the following 4 areas: universal healthcare, values and ethics, evidence-based interventions, and process transformation. The framework…
Priority Setting/Ethics | Health/Medicine | Global | Health Systems -
ArticleWeb Portal 2017PLoS Collection: Prevention, Diagnosis and Treatment of Sexually Transmitted Infections
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted …
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted infections (STIs) occur each day, incurring a very substantial burden of morbidity, mortality and additional infections. The pathogens responsible include bacteria, parasites and viruses, and intensive research is needed to address the substantial barriers to diagnosis and treatment of STIs, and the behavioral challenges of prevention. This PLOS collection, published in collaboration with WHO, focuses on global policy and systems…
Priority Setting/Ethics | Health/Medicine | Middle East & North Africa | Health Systems | Costing Methods | Mathematical Models | Dynamic Transmission | Cost-Effectiveness Analysis | Infectious Diseases | Economics/Finance | Sub-Saharan Africa | Latin America & Caribbean | Asia & Pacific