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Resources Repository
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BookPublication 1996Cost-Effectiveness in Health and Medicine, 1st Edition
In 1993, the US Public Health Service convened a panel of 13 nongovernment scientists and …
In 1993, the US Public Health Service convened a panel of 13 nongovernment scientists and scholars with expertise in economics, clinical medicine, ethics, and statistics to review the state of cost-effectiveness analysis and to develop recommendations for its conduct and use in health and medicine. Publishing their results in 1996, they proposed the most explicit set of guidelines (together with their rationale) ever defined on the conduct of CEAs. The panel recommended analysts include a "reference-case"…
Priority Setting/Ethics | Preferences/Values | Cost-Effectiveness Analysis | North America | Policy/Regulation | Costing Methods | Health Outcomes | Evidence Synthesis | Value of Information | Health Systems | Economics/Finance | Health/Medicine -
ArticlePublication 2010Alternative Strategies to Reduce Maternal Mortality in India: A Cost-Effectiveness Analysis
This article, published in PLoS Medicine, conducted a cost-effectiveness analysis of strategies to improve pregnancy …
This article, published in PLoS Medicine, conducted a cost-effectiveness analysis of strategies to improve pregnancy and childbirth safety in India. Country- and region-specific data were synthesized using a computer-based model that simulates the natural history of pregnancy and pregnancy-associated complications in individual women, and considers delivery location, attendant, and facility level. Model validation compared projected maternal indicators with empiric data. Strategies consisted of improving coverage of effective interventions that could be provided individually or packaged…
Microsimulation | Cost-Effectiveness Analysis | Asia & Pacific | Maternal/Reproductive Health | Evidence Synthesis | Mathematical Models | Economics/Finance | Health/Medicine | Global -
ArticlePublication 2023Benefits and Costs of COVID-19 Vaccine Mandates
Written mid-pandemic, this article evaluates the direct costs and health benefits of requiring COVID-19 vaccinations …
Written mid-pandemic, this article evaluates the direct costs and health benefits of requiring COVID-19 vaccinations for U.S. federal employees and healthcare and private sector workers. These mandates were controversial and some were halted by litigation. If they had been implemented as intended, the net benefits would depend on the course of the pandemic. If a more transmissible variant (such as Omicron) emerges, the net benefits may be large. If the pandemic instead fades, the benefits…
Benefit-Cost Analysis | State-Transition | North America | Policy/Regulation | Mathematical Models | Infectious Diseases | Business/Industry | Economics/Finance | Government/Law | Health/Medicine -
ArticlePublication 2022Emerging Therapies for COVID-19: The Value of Information From More Clinical Trials
The COVID-19 pandemic necessitated time-sensitive policy and implementation decisions regarding new therapies in the face …
The COVID-19 pandemic necessitated time-sensitive policy and implementation decisions regarding new therapies in the face of uncertainty. This study aimed to quantify consequences of approving therapies or pursuing further research. The authors used a cohort state-transition model for hospitalized patients with COVID-19 to estimate quality-adjusted life-years (QALYs) and costs associated with multiple drug regimens and usual care. For each they assessed immediate approval, use only in research, emergency use authorization or reject. They conducted cost-effectiveness…
Benefit-Cost Analysis | State-Transition | North America | Policy/Regulation | Value of Information | Infectious Diseases | Economics/Finance | Europe -
ReportPublication 2021Valuing COVID-19 Mortality and Morbidity Risks
In this report, the researchers develop an approach for valuing COVID-19 mortality and morbidity risk …
In this report, the researchers develop an approach for valuing COVID-19 mortality and morbidity risk reductions that builds on the U.S. Department of Health and Human Services (HHS) Guidelines for Regulatory Impact Analysis. They review the differences between COVID-19 mortality risks and the types of risks that are more commonly studied, and find that the impacts of these differences on the value of mortality risk reductions (the value per statistical life, VSL) are uncertain. They…
Preferences/Values | Benefit-Cost Analysis | North America | Policy/Regulation | Infectious Diseases | Government/Law -
ArticlePublication 2021Identifying Credible Sources of Health Information in Social Media: Principles and Attributes
Social media is widely used as a source of health information for the general public. …
Social media is widely used as a source of health information for the general public. The potential for information shared through social media to influence health outcomes necessitates action by social media platforms to enhance access and exposure to high-quality, science-based information. This paper summarizes the work of an independent advisory group convened by the National Academy of Medicine that deliberated and gathered information to develop a set of initial principles and attributes that could…
Preferences/Values | Decision Psychology | North America | Policy/Regulation | Social Determinants | Culture/Society | Education/Labor | Health/Medicine | Science/Technology -
ArticlePublication 2021Scientific Theory of Gist Communication and Misinformation Resistance
This article presents a framework for understanding how misinformation shapes decision-making, which has cognitive representations …
This article presents a framework for understanding how misinformation shapes decision-making, which has cognitive representations of gist at its core. The author discusses how the framework goes beyond prior work, and how it can be implemented so that valid scientific messages are more likely to be effective, remembered, and shared through social media, while misinformation is resisted. The distinction between mental representations of the rote facts of a message – its verbatim representation – and…
Preferences/Values | Decision Psychology | North America | Policy/Regulation | Social Determinants | Culture/Society | Health/Medicine | Science/Technology -
Online LearningVideo, Teaching Resource 2021Reporting on COVID-19 Vaccines at the Intersection of Science and Politics
Journalists play a vital role in communicating to the public about COVID-19 vaccines, and currently …
Journalists play a vital role in communicating to the public about COVID-19 vaccines, and currently under challenging circumstances. The science surrounding COVID-19 is rapidly changing, vaccines have been developed at “warp speed” using a new approach, and misinformation is on the rise. Moreover, current and historical injustices and inequities, as well as heightened political polarization, affect what information is consumed, trusted, and acted upon. This webinar offers an opportunity for members of the media to…
Preferences/Values | Decision Psychology | North America | Policy/Regulation | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | Science/Technology -
ArticlePublication 2021Measuring the News and Its Impact on Democracy
Since the 2016 U.S. presidential election, the deliberate spread of misinformation online, and on social …
Since the 2016 U.S. presidential election, the deliberate spread of misinformation online, and on social media in particular, has generated extraordinary concern, in large part because of its potential effects on public opinion, political polarization, and ultimately democratic decision making. Recently, however, some have argued that both the prevalence and consumption of “fake news” per se is extremely low compared with other types of news and news-relevant content. Although neither prevalence nor consumption is a…
Preferences/Values | Decision Psychology | North America | Policy/Regulation | Social Determinants | Culture/Society | Science/Technology