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Resources Repository
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ArticlePublication 2009Cost-Effectiveness of Alternative Pregnancy Termination Strategies in Mexico City
This study evaluated the health and economic outcomes associated with three alternative first-trimester abortion techniques …
This study evaluated the health and economic outcomes associated with three alternative first-trimester abortion techniques in Mexico City using a computer-based model to simulate induced abortion and its potential complications. Strategies included alternative modalities for first-trimester pregnancy termination: hospital-based dilatation and curettage (D&C), hospital-based manual vacuum aspiration (MVA), clinic-based MVA and medical abortion using vaginal misoprostol. Outcomes included number of complications, lifetime costs, life expectancy, and quality-adjusted life expectancy. Assuming all options were equally available,…
Cost-Effectiveness Analysis | Health Outcomes | Health/Medicine | Maternal/Reproductive Health | State-Transition | Latin America & Caribbean -
ArticlePublication 2023Simulation-Based Comparative Effectiveness Analysis of Policies to Improve Global Maternal Health Outcomes
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) …
The Sustainable Development Goals include a target to reduce the global maternal mortality ratio (MMR) to less than 70 maternal deaths per 100,000 live births by 2030, with no individual country exceeding 140. However, on current trends the goals are unlikely to be met. The authors used an empirically calibrated Global Maternal Health microsimulation model, which simulates individual women in 200 countries and territories to evaluate the impact of different interventions and strategies from 2022…
Health Outcomes | Health/Medicine | Maternal/Reproductive Health | Mathematical Models | Microsimulation | Calibration/Validation | Health Systems | Clinical Care | Global -
ArticlePublication 2023Single-Arm Trial Design Estimates Efficacy
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and …
Studies to confirm the efficacy of a single HPV vaccine dose, of vaccine durability, and of vaccination modifications are needed, but randomized controlled trials are costly and face logistical and ethical challenges. In this study, the authors demonstrate proof-of-principle that a single-arm design yields valid estimates with similar precision to a randomized controlled trial.
Health Outcomes | Health/Medicine | Maternal/Reproductive Health | Infectious Diseases | Policy/Regulation | Global -
ArticlePublication 2022Trauma Care in Public and Private Hospitals in Addis Ababa, Ethiopia: Cross-Sectional Observational Study
This study examines the financial risks associated with seeking trauma care for road traffic injuries …
This study examines the financial risks associated with seeking trauma care for road traffic injuries in Addis Ababa, Ethiopia. Conducting a cross-sectional survey from December 2018 to February 2019 in three public and one private hospital, the research analyzes out-of-pocket (OOP) expenditures related to trauma care. Data from 452 trauma cases are collected, encompassing both medical and non-medical costs. Catastrophic health expenditures, defined as OOP health expenditures exceeding 10% of total household expenditures, are assessed,…
Cost-Effectiveness Analysis | Health/Medicine | Injuries/Accidents | Sub-Saharan Africa -
ArticlePublication 2019CEA of Maternal and Neonatal Health Interventions
This article, published in Health Policy and Planning, examines the cost-effectiveness of several maternal and …
This article, published in Health Policy and Planning, examines the cost-effectiveness of several maternal and neonatal health (MNH) interventions in an Ethiopian setting. The authors employ a static life table model to estimate the health impact of a 20% increase in intervention coverage relative to baseline. The results indicate that many MNH interventions are highly cost-effective. This evidence can be useful to inform the ongoing essential health services package revision in Ethiopia.
Cost-Effectiveness Analysis | Health/Medicine | Maternal/Reproductive Health | Child/Nutrition | Health Systems | Sub-Saharan Africa -
ArticlePublication 2019Modelling Hospital Operations from Paper Registry Data
This article, published in BMJ Global Health, aims to evaluate operations management techniques, which are …
This article, published in BMJ Global Health, aims to evaluate operations management techniques, which are underutilized in the Ethiopian health system. Previous research has outlined the limitations of paper-based patient records, but few studies have examined their potential utility for improving management of hospital operations. The authors use data collected from paper registries in an Ethiopian obstetrics ward at Addis Ababa’s Tikur Anbessa Specialized Hospital, Ethiopia’s largest university hospital, to model the ward’s operations. The…
Operations Research | Health/Medicine | Maternal/Reproductive Health | Mathematical Models | Health Systems | Sub-Saharan Africa -
ArticlePublication 2018Cost-Effectiveness of Strategies to Prevent Road Traffic Injuries in Eastern Sub-Saharan Africa and Southeast Asia: New Results from WHO-CHOICE
The authors applied a generalized cost-effectiveness analysis (GCEA) approach, applying a null reference case, in …
The authors applied a generalized cost-effectiveness analysis (GCEA) approach, applying a null reference case, in which the effects of currently implemented interventions were subtracted from current rates of burden, in order to identify the most efficient package of interventions that could be applied to Road Traffic Injuries (RTIs). They used a population model to estimate costs and effectiveness of interventions over a 100 year time frame in eastern sub-Saharan Africa and Southeast Asia. All heath…
Cost-Effectiveness Analysis | Science/Technology | Injuries/Accidents | State-Transition | Policy/Regulation | Culture/Society | Sub-Saharan Africa | Asia & Pacific -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Population Health Outcomes
In this teaching pack on Population Health Outcomes, students learn how to describe outcomes at a …
In this teaching pack on Population Health Outcomes, students learn how to describe outcomes at a population level using quality adjusted life years (QALYs), including how to calculate QALYs, the assumptions underlying them, how to derive QALYs using indirect utility measures, and what are some of the ethical criticisms of QALYs. Materials include an instructor’s note, videos, companion slides, a glossary, an annotated bibliography, and sample exercises. Learning Objectives Define Quality-Adjusted Life Years (QALYs)…
Health Outcomes | Health/Medicine | Injuries/Accidents | Preferences/Values | Priority Setting/Ethics | College | Graduate | Doctoral -
ArticlePublication 2017Adolescent Pregnancy Prevention Program in Zambia
This article, published in Trials, outlines a protocol for a cost-benefit analysis (CBA) and an …
This article, published in Trials, outlines a protocol for a cost-benefit analysis (CBA) and an extended cost-effectiveness analysis (ECEA) of a comprehensive adolescent pregnancy prevention program in Zambia. The study will be conducted alongside a cluster-randomized controlled trial, which tests the hypothesis that economic support with or without community dialogue is an effective strategy for reducing adolescent childbearing rates. The ECEA will estimate the costs of the intervention packages per unit health and non-health gain…
Cost-Effectiveness Analysis | Health/Medicine | Maternal/Reproductive Health | Child/Nutrition | Social Determinants | Health Systems | Sub-Saharan Africa