Resources Repository
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BookPublication 1980Clinical Decision Analysis
This text was conceived and developed in the Harvard T.H. Chan School of Public Health …
This text was conceived and developed in the Harvard T.H. Chan School of Public Health at the Center for the Analysis of Health Practices. The book had its origins in a set of classroom materials developed during the academic year 1974-75 for an elective course in medical decision making at the Harvard Medical School. In this book students are shown how to structure clinical decision problems, how to systematically formulate the intertwining roles of diagnosis and treatment, how to…
Cost-Effectiveness Analysis | Health Outcomes | Value of Information | North America | Child/Nutrition | Probability/Bayes | Preferences/Values | Costing Methods | Test Performance | State-Transition | Decision Analysis | Infectious Diseases | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Global | Europe | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ArticlePublication 2019Estimation of Eating Disorders Prevalence by Age and Associations with Mortality in a Simulated Nationally Representative U.S. Cohort
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, …
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, and estimates the association of increased treatment coverage with ED-related mortality. Using an individual-level Markov state transition model calibrated to nationally-representative US survey data from 2007 and 2011, the authors simulated a virtual cohort of 100,000 individuals (50% male) from birth to age 40 years and modelled 4 ED diagnoses: anorexia nervosa, bulimia nervosa, binge eating disorder, and other specified…
Calibration/Validation | Health Outcomes | North America | Child/Nutrition | Microsimulation | Mental Health -
ArticlePublication 2021Measuring the Impact of COVID-19 Vaccine Misinformation on Vaccination Intent in the U.K. and U.S.
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight …
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight the COVID-19 pandemic, but high uptake achievement will be a challenge and may be impeded by online misinformation. This article is a randomized controlled trial in the U.K. and the U.S. with the objective to quantify how exposure to online misinformation around COVID-19 vaccines affects intent to vaccinate to protect oneself or others. The authors report that in both countries…
North America | Child/Nutrition | Decision Psychology | Preferences/Values | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | Science/Technology | Europe -
ArticlePublication 2017Misinformation Lingers in Memory: Failure of Three Pro-Vaccination Strategies
People's inability to update their memories in light of corrective information may have important public …
People's inability to update their memories in light of corrective information may have important public health consequences, as in the case of vaccination choice. The authors compare three potentially effective strategies in vaccine promotion: (1) one contrasting myths vs. facts, (2) one employing fact and icon boxes, and (3) one showing images of non-vaccinated sick children. Beliefs in the autism/vaccines link and in vaccines side effects, along with intention to vaccinate a future child, were…
North America | Child/Nutrition | Decision Psychology | Preferences/Values | Infectious Diseases | Culture/Society | Government/Law | Health/Medicine | Science/Technology -
ArticlePublication 2019Countering Misinformation with Lessons from Public Health
The internet is often praised as a tool for freedom of speech, democracy, and truth. …
The internet is often praised as a tool for freedom of speech, democracy, and truth. However, the internet increasingly has become polluted by misinformation – the inadvertent spread of misleading and false information – and disinformation – the deliberate and coordinated spread of misleading and false information. Individuals online knowingly and unknowingly spread dangerous rumors and propaganda at an alarming rate, which can mislead or manipulate the worldview of those who encounter it. False information…
North America | Child/Nutrition | Decision Psychology | Preferences/Values | Infectious Diseases | Social Determinants | Culture/Society | Health/Medicine | Science/Technology | Global -
ArticlePublication 2017Estimated Economic Impact of Vaccinations in 73 LMIC, 2001-2020
This analysis estimates the economic impact likely to be achieved by efforts to vaccinate against 10 …
This analysis estimates the economic impact likely to be achieved by efforts to vaccinate against 10 vaccine-preventable diseases between 2001 and 2020 in 73 low- and middle-income countries largely supported by Gavi, the Vaccine Alliance. The authors used health impact models to estimate the economic impact of achieving forecasted coverages for vaccination against Haemophilus influenzae type b, hepatitis B, human papillomavirus, Japanese encephalitis, measles, Neisseria meningitidis serogroup A, rotavirus, rubella, Streptococcus pneumoniae and yellow fever. In…
Cost-Effectiveness Analysis | Health Outcomes | Latin America & Caribbean | Child/Nutrition | State-Transition | Dynamic Transmission | Microsimulation | Infectious Diseases | Health Systems | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Asia & Pacific -
OrganizationWeb Portal 2024Agency for Healthcare Research and Quality (AHRQ)
The Agency for Healthcare Research and Quality (AHRQ) is the nation's lead federal agency for …
The Agency for Healthcare Research and Quality (AHRQ) is the nation's lead federal agency for research on health care quality, costs, outcomes and patient safety. AHRQ is the health services research arm of the U.S. Department of Health and Human Services (HHS), complementing the biomedical research mission of its sister agency, the National Institutes of Health. The agency is home to research centers that specialize in major areas of health care research, including: clinical practice…
Cost-Effectiveness Analysis | Health Outcomes | North America | Child/Nutrition | Costing Methods | Test Performance | Decision Analysis | Technology Assessment | Infectious Diseases | Maternal/Reproductive Health | Chronic Disease/Risk | Mental Health | Injuries/Accidents | Social Determinants | Health Systems | Policy/Regulation | Economics/Finance | Government/Law | Health/Medicine | Science/Technology -
ArticlePublication 2010Health and Economic Impact of Rotavirus Vaccination in GAVI-Eligible Countries
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately …
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately borne by children in low-income countries. Motivated by the global recommendation by the WHO that all countries include infant rotavirus vaccination in their national immunization programs, the objective of this analysis was to provide information on the expected health, economic and financial consequences of rotavirus vaccines in the 72 GAVI support-eligible countries. The authors synthesized population-level data from various sources (primarily from…
Cost-Effectiveness Analysis | Health Outcomes | Latin America & Caribbean | Child/Nutrition | Mathematical Models | State-Transition | Infectious Diseases | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Asia & Pacific -
ArticlePublication 2023Cost-Effectiveness and Long-Term Savings of the Bright Bodies Intervention for Childhood Obesity
This study evaluates the cost-effectiveness of Bright Bodies, a family-based pediatric weight management intervention, using …
This study evaluates the cost-effectiveness of Bright Bodies, a family-based pediatric weight management intervention, using a microsimulation model projecting 10-year BMI trajectories of children with obesity. Data from a randomized controlled trial and follow-up study inform the model, which estimates the intervention's effect on BMI reduction and incremental costs compared to clinical control. Results indicate that Bright Bodies reduces BMI by 1.67 kg/m2 per year over 10 years, with an incremental cost of $360 per…
Cost-Effectiveness Analysis | North America | Child/Nutrition | Microsimulation | Health/Medicine