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Resources Repository
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ArticlePublication 2016Cost-Effectiveness of Routine Vaccination With a Live-Attenuated Dengue Vaccine: Model Comparison
Large Phase III trials across Asia and Latin America have demonstrated the efficacy of a recombinant, …
Large Phase III trials across Asia and Latin America have demonstrated the efficacy of a recombinant, live-attenuated dengue vaccine (Dengvaxia) over the first 25 months following vaccination. Subsequent data collected in the longer-term follow-up phase, however, have raised concerns about a potential increase in hospitalization risk of subsequent dengue infections, in particular among young, dengue-naïve vaccinees. This paper reports predictions from eight independent modelling groups on the long-term safety, public health impact, and cost-effectiveness of routine…
Mathematical Models | Cost-Effectiveness Analysis | Dynamic Transmission | Climate/Environment | Health Systems | Child/Nutrition | Infectious Diseases | Global Governance | Economics/Finance | Health/Medicine | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2015Extended Cost-Effectiveness Analysis of Treatment and Prevention of Diarrhoea in Ethiopia
This article, published in BMJ Open, aims to illustrate the size and distribution of benefits …
This article, published in BMJ Open, aims to illustrate the size and distribution of benefits due to the treatment and prevention of diarrhoea (i.e., rotavirus vaccination) in Ethiopia. The authors use an economic model to examine the impacts of universal public finance (UPF) of diarrhoeal treatment alone, as opposed to diarrhoeal treatment along with rotavirus vaccination using extended cost-effectiveness analysis (ECEA). The study finds that diarrhoeal treatment paired with rotavirus vaccination is more cost effective…
Priority Setting/Ethics | Cost-Effectiveness Analysis | Climate/Environment | Health Systems | Social Determinants | Child/Nutrition | Costing Methods | Health Outcomes | Infectious Diseases | Environmental Health | Economics/Finance | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2020Online Competition between Pro- and Anti-Vaccination Views
Distrust in scientific expertise is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, …
Distrust in scientific expertise is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks as happened for measles in 2019. Homemade remedies and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice. There is a lack of understanding about how this distrust evolves at the system level. Authors provide a map of the contention surrounding vaccines that has…
Preferences/Values | Decision Psychology | Government/Law | Health Systems | Social Determinants | Infectious Diseases | Policy/Regulation | Culture/Society | Health/Medicine | Science/Technology | North America -
ArticlePublication 2016Accounting for Technical, Ethical, and Political Factors in Priority Setting
This article investigates two cases of priority setting to explore how, in addition to technical …
This article investigates two cases of priority setting to explore how, in addition to technical considerations, ethical and political factors shape the allocation of health resources. First, they discuss how Thai authorities adjudicated a coverage decision for HLA-B*1502 screening, which meets the national cost-effectiveness threshold for only some of the conditions it can detect. Second, they consider England’s Cancer Drugs Fund to investigate the interplay of technical decision making and political reality. The findings suggest four concluding…
Priority Setting/Ethics | Cost-Effectiveness Analysis | Government/Law | Climate/Environment | Health Systems | Chronic Disease/Risk | Policy/Regulation | Health/Medicine | Science/Technology | Global | Europe -
ArticlePublication 2017Policy Makers, the International Community and the Population: Case Study on HIV/AIDS
A four-period game is developed between a policy maker, the international community, and the population. …
A four-period game is developed between a policy maker, the international community, and the population. This research supplements, through implementing strategic interaction, earlier research analyzing "one player at a time." The first two players distribute funds between preventing and treating diseases. The population reacts by degree of risky behavior which may cause no disease, disease contraction, recovery, sickness/death. More funds to prevention implies less disease contraction but higher death rate given disease contraction. The cost…
Priority Setting/Ethics | Mathematical Models | Decision Psychology | Government/Law | Health Systems | Infectious Diseases | Global Governance | Economics/Finance | Health/Medicine | Global -
ArticlePublication 2020Infectious Disease Pandemic Planning and Response: Incorporating Decision Analysis
During a pandemic, decisions must be made under rapidly changing, uncertain conditions. Despite advances in …
During a pandemic, decisions must be made under rapidly changing, uncertain conditions. Despite advances in analytical methods for gaining early situational awareness (i.e., of a disease’s transmissibility and severity) and for predicting the likely effectiveness of interventions, a major gap exists globally in terms of integrating this information in policy documents. The authors argue that mathematical and statistical models are important tools for pandemic planning and response. Once an outbreak of pandemic potential has been…
Mathematical Models | Decision Analysis | Government/Law | Health Systems | Health/Medicine | Global -
ArticlePublication 2021Why the Backfire Effect Does Not Explain the Durability of Political Misperceptions
Previous research indicated that corrective information can sometimes provoke a so-called “backfire effect” in which …
Previous research indicated that corrective information can sometimes provoke a so-called “backfire effect” in which respondents more strongly endorsed a misperception about a controversial political or scientific issue when their beliefs or predispositions were challenged. This article shows how subsequent research and media coverage seized on this finding, distorting its generality and exaggerating its role relative to other factors in explaining the durability of political misperceptions. To the contrary, an emerging research consensus finds that…
Preferences/Values | Decision Psychology | Government/Law | Social Determinants | Culture/Society | Health/Medicine | Science/Technology | North America -
ArticlePublication 2021Misinformation in and About Science
Humans learn about the world by collectively acquiring information, filtering it, and sharing what we …
Humans learn about the world by collectively acquiring information, filtering it, and sharing what we know. Misinformation undermines this process. The repercussions are extensive. Without reliable and accurate sources of information, we cannot hope to halt climate change, make reasoned democratic decisions, or control a global pandemic. Most analyses of misinformation focus on popular and social media, but the scientific enterprise faces a parallel set of problems – from hype and hyperbole to publication bias…
Preferences/Values | Decision Psychology | Government/Law | Social Determinants | Culture/Society | Science/Technology | Global | North America -
ArticlePublication 2021Misinformation and Public Opinion of Science and Health
This article summarizes the literature on misinformation, beginning with an overview of the most common …
This article summarizes the literature on misinformation, beginning with an overview of the most common definitions of misinformation (and related terms) in the communication literature and then a review of academic studies in the areas of science and health. The author acknowledges four overarching questions that have emerged prominently in recent years: (1) What does “misinformation” (and the terms that are oftentimes treated synonymously) mean? (2) How big of a problem is it in areas…
Preferences/Values | Decision Psychology | Climate/Environment | Social Determinants | Culture/Society | Energy/Engineering | Education/Labor | Science/Technology | Global | North America