- probability/bayes
- preferences/values
- priority setting/ethics
- test performance
- calibration/validation
- approaches and applications
- risk analysis
- benefit-cost analysis
- cost-effectiveness analysis
- technology assessment
- operations research
- child/nutrition
- injuries/accidents
- social determinants
- clinical care
Resources Repository
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ArticlePublication 2010Health and Economic Impact of Rotavirus Vaccination in GAVI-Eligible Countries
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately …
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately borne by children in low-income countries. Motivated by the global recommendation by the WHO that all countries include infant rotavirus vaccination in their national immunization programs, the objective of this analysis was to provide information on the expected health, economic and financial consequences of rotavirus vaccines in the 72 GAVI support-eligible countries. The authors synthesized population-level data from various sources (primarily from…
Cost-Effectiveness Analysis | Child/Nutrition | Health Outcomes | Mathematical Models | State-Transition | Infectious Diseases | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
Online LearningVideo, Teaching Resource 2010TED Talk. The Art of Choosing
In this talk, Sheena Iyengar challenges three key assumptions of the standard economic model of …
In this talk, Sheena Iyengar challenges three key assumptions of the standard economic model of choice: 1) that it is always in the individual’s best interests to choose for themselves, 2) that more choice are always better, and 3) that we should never say no to choice. In particular, she highlights differences in the way people view choice in the US and in other parts of the world. Iyengar argues that if we were to…
Preferences/Values | Child/Nutrition | Decision Psychology | Education/Labor | High School | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership -
ReviewPublication 2010Validation of Population-Based Disease Simulation Models: A Review
This article develops a framework for validating population-based chronic disease simulation models, and reviews the …
This article develops a framework for validating population-based chronic disease simulation models, and reviews the principles and methods for such models. While computer simulation models are used increasingly to support public health research and policy, questions about their quality persist. Based on the review, the authors formulated a set of recommendations for gathering evidence of model credibility. They find that evidence of model credibility derives from examining: 1) the process of model development, 2) the…
Calibration/Validation | Social Determinants | Mathematical Models | Chronic Disease/Risk | Health/Medicine -
ArticlePublication 2009Cost-Effectiveness of HPV Vaccination and Cervical Cancer Screening in Women Aged 30+ Years in the U.S.
The objective of the study was to assess the health and economic outcomes of HPV …
The objective of the study was to assess the health and economic outcomes of HPV vaccination in older U.S. women. The authors conducted a cost-effectiveness analysis with an empirically calibrated model using data from published literature; interventions included HPV vaccination added to screening strategies that differ by test (cytology or HPV DNA testing), frequency, and start age versus screening alone.They found that in the context of annual or biennial screening, HPV vaccination of women aged…
Cost-Effectiveness Analysis | Clinical Care | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Science/Technology | North America -
ArticlePublication 2007Modeling HPV and Cervical Cancer in the U.S. for Analyses of Screening and Vaccination
This paper discusses a model of human papillomavirus (HPV) and cervical cancer that incorporates uncertainty …
This paper discusses a model of human papillomavirus (HPV) and cervical cancer that incorporates uncertainty about the natural history of disease that was used to provide quantitative insight into U.S. policy choices for cervical cancer prevention. The authors developed a stochastic microsimulation of cervical cancer that distinguishes different HPV types by their incidence, clearance, persistence, and progression. For each set of sampled input parameters, likelihood-based goodness-of-fit (GOF) scores were computed based on comparisons between model-predicted…
Calibration/Validation | Clinical Care | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Health/Medicine | Science/Technology | North America -
ReviewPublication 1978Basic Principles of ROC Analysis
The limitations of diagnostic "accuracy" as a measure of decision performance require introduction of the …
The limitations of diagnostic "accuracy" as a measure of decision performance require introduction of the concepts of the "sensitivity" and "specificity" yet even these do not provide a unique description of diagnostic performance because they depend on the arbitrary selection of a decision threshold. The receiver operating characteristic (ROC) curve is shown to be a simple yet complete empirical description of this decision threshold effect, indicating all possible combinations of the relative frequencies of the…
Test Performance | Clinical Care | Health/Medicine