Resources Repository
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ArticlePublication 2019Estimation of Eating Disorders Prevalence by Age and Associations with Mortality in a Simulated Nationally Representative U.S. Cohort
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, …
This analysis models the individual-level disease dynamics of eating disorders (ED) in the United States, and estimates the association of increased treatment coverage with ED-related mortality. Using an individual-level Markov state transition model calibrated to nationally-representative US survey data from 2007 and 2011, the authors simulated a virtual cohort of 100,000 individuals (50% male) from birth to age 40 years and modelled 4 ED diagnoses: anorexia nervosa, bulimia nervosa, binge eating disorder, and other specified…
Microsimulation | Mental Health | Child/Nutrition | Health Outcomes | Calibration/Validation | North America -
ArticlePublication 2021Measuring the Impact of COVID-19 Vaccine Misinformation on Vaccination Intent in the U.K. and U.S.
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight …
Widespread acceptance of a vaccine for SARS-CoV-2 will be the next major step to fight the COVID-19 pandemic, but high uptake achievement will be a challenge and may be impeded by online misinformation. This article is a randomized controlled trial in the U.K. and the U.S. with the objective to quantify how exposure to online misinformation around COVID-19 vaccines affects intent to vaccinate to protect oneself or others. The authors report that in both countries…
Decision Psychology | Child/Nutrition | Infectious Diseases | Preferences/Values | Social Determinants | Culture/Society | Health/Medicine | Science/Technology | North America | Europe -
ArticlePublication 2017Misinformation Lingers in Memory: Failure of Three Pro-Vaccination Strategies
People's inability to update their memories in light of corrective information may have important public …
People's inability to update their memories in light of corrective information may have important public health consequences, as in the case of vaccination choice. The authors compare three potentially effective strategies in vaccine promotion: (1) one contrasting myths vs. facts, (2) one employing fact and icon boxes, and (3) one showing images of non-vaccinated sick children. Beliefs in the autism/vaccines link and in vaccines side effects, along with intention to vaccinate a future child, were…
Decision Psychology | Child/Nutrition | Infectious Diseases | Preferences/Values | Culture/Society | Government/Law | Health/Medicine | Science/Technology | North America -
ArticlePublication 2019Countering Misinformation with Lessons from Public Health
The internet is often praised as a tool for freedom of speech, democracy, and truth. …
The internet is often praised as a tool for freedom of speech, democracy, and truth. However, the internet increasingly has become polluted by misinformation – the inadvertent spread of misleading and false information – and disinformation – the deliberate and coordinated spread of misleading and false information. Individuals online knowingly and unknowingly spread dangerous rumors and propaganda at an alarming rate, which can mislead or manipulate the worldview of those who encounter it. False information…
Decision Psychology | Child/Nutrition | Infectious Diseases | Preferences/Values | Social Determinants | Culture/Society | Health/Medicine | Science/Technology | Global | North America -
Resource PackWeb Portal, Teaching Resource 2018Resource Pack: Cervical Cancer Models
This resource pack, curated by the Center for Health Decision Science, is a collection of …
This resource pack, curated by the Center for Health Decision Science, is a collection of models of HPV-related cervical cancer, differing in design, structure and features based on analytic objectives. In many ways, HPV and its related diseases represent a prototypical public health problem given the communicable and non-communicable nature of disease, opportunities for intervention along the entire disease spectrum (e.g., primary and secondary prevention, diagnosis, treatment), the varied ages at which interventions are targeted…
Dynamic Simulation | Microsimulation | Infectious Diseases | Mathematical Models | State-Transition | Dynamic Transmission | Calibration/Validation | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health Systems | Clinical Care | Business/Industry | Economics/Finance | Health/Medicine | Science/Technology | Global -
ArticlePublication 2017Estimated Economic Impact of Vaccinations in 73 LMIC, 2001-2020
This analysis estimates the economic impact likely to be achieved by efforts to vaccinate against 10 …
This analysis estimates the economic impact likely to be achieved by efforts to vaccinate against 10 vaccine-preventable diseases between 2001 and 2020 in 73 low- and middle-income countries largely supported by Gavi, the Vaccine Alliance. The authors used health impact models to estimate the economic impact of achieving forecasted coverages for vaccination against Haemophilus influenzae type b, hepatitis B, human papillomavirus, Japanese encephalitis, measles, Neisseria meningitidis serogroup A, rotavirus, rubella, Streptococcus pneumoniae and yellow fever. In…
Microsimulation | Child/Nutrition | Infectious Diseases | Health Outcomes | State-Transition | Dynamic Transmission | Cost-Effectiveness Analysis | Health Systems | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2017Using Data-Driven Agent-Based Models to Forecast Emerging Infectious Diseases
This paper describes an agent-based model framework developed to forecast the 2014-15 Ebola epidemic, which …
This paper describes an agent-based model framework developed to forecast the 2014-15 Ebola epidemic, which was subsequently used in the Ebola forecasting challenge. Producing timely and reliable forecasts for an epidemic of an emerging infectious disease is a challenge. Epidemiologists and policy makers have to deal with poor data quality, limited understanding of the disease dynamics, a rapidly changing social environment and the uncertainty around the effects of various interventions in place. In this setting,…
Dynamic Simulation | Microsimulation | Infectious Diseases | Calibration/Validation | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2016Cost-Effectiveness of Diagnosing HIV Infection During Early Infancy in South Africa
In this study the clinical impact and cost-effectiveness of four different early infant HIV diagnosis …
In this study the clinical impact and cost-effectiveness of four different early infant HIV diagnosis (EID) testing strategies for HIV-exposed infants in South Africa were compared using a microsimulation model. The strategies included (1) no EID (diagnosis only after illness), (2) and (3) testing once (at birth alone or at 6 weeks of age alone), and (4) testing twice (at birth and 6 weeks of age). Findings showed that the testing at birth alone strategy…
Microsimulation | Child/Nutrition | Infectious Diseases | Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa -
ReviewPublication 2016Decision Support for Infectious Disease Control
This report from RAND reviews decision-support tools, including models and nonmodeling approaches, that are relevant to …
This report from RAND reviews decision-support tools, including models and nonmodeling approaches, that are relevant to infectious disease prevention, detection, and response and aligns these tools with real-world policy questions that the tools can help address. This overview is designed to help modelers and other technical experts understand the questions that policymakers will raise and the decisions they must make. The report also presents policymakers with the capabilities and limitations of the different tools that may…
Dynamic Simulation | Microsimulation | Infectious Diseases | Mathematical Models | State-Transition | Dynamic Transmission | Global Governance | Government/Law | Health/Medicine | Military/Defense | Global