- methods and metrics
- costing methods
- health outcomes
- evidence synthesis
- test performance
- value of information
- mathematical models
- approaches and applications
- risk analysis
- benefit-cost analysis
- cost-effectiveness analysis
- technology assessment
- operations research
- business/industry
- culture/society
- government/law
- health/medicine
Resources Repository
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Lesson/ModuleWeb Portal, Teaching Resource 2016Placing a Bet: New Therapy for Parkinson's Disease
This module is intended for use by business school students. It examines the decision-making process …
This module is intended for use by business school students. It examines the decision-making process at a pharmaceutical company as its chief operating officer decides whether to invest in the development and licensing of a promising treatment for Parkinson’s disease. The module is structured around a drug development case that provides students with opportunities to: (1) analyze a rich and realistic description of the complex scientific and medical results associated with a promising therapeutic molecule…
Test Performance | Technology Assessment | Government/Law | Health/Medicine | Business/Industry | Chronic Disease/Risk | Policy/Regulation | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Drug-Induced Birth Defects
Using the currently topical issue of whether SSRI (Selective Serotonin Reuptake Inhibitor) anti-depressants cause birth …
Using the currently topical issue of whether SSRI (Selective Serotonin Reuptake Inhibitor) anti-depressants cause birth defects, the module aims to provide students with a general understanding of the following: (1) human risk factor causation as determined by epidemiologic methods; (2) the limits of non-human toxicological evidence to the assessment of causality in humans; (3) the importance of pharmacovigilance for all medications; (4) special difficulties in identifying causes of human birth defects; (5) the importance of…
Evidence Synthesis | Risk Analysis | Health Outcomes | Government/Law | Health/Medicine | Child/Nutrition | Chronic Disease/Risk | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Vaccines
This module engages students in learning about association and causation in the context of vaccines, …
This module engages students in learning about association and causation in the context of vaccines, their side effects, and legal issues that could arise as a result of side effects associated with vaccinations. The module employs five case studies. In the first two case studies, a child receives a vaccination, and students must determine whether an event (vaccination) causes a side effect in the child. In the third case study, a child who has not…
Technology Assessment | Risk Analysis | Health Outcomes | Government/Law | Health/Medicine | Infectious Diseases | Health Systems | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Scientific Evidence of Factual Causation
This module examines three scientific areas that provide evidence bearing on causation in the “toxic …
This module examines three scientific areas that provide evidence bearing on causation in the “toxic tort” or environmental disease context: epidemiology, toxicology, and genetics. These scientific disciplines are used in civil lawsuits and in regulatory proceedings in which causation or risk is an issue. The module is appropriate for non-scientist law students as well as others interested in learning the science of toxic tort causation, including practicing attorneys, judges, and public policy and public health…
Evidence Synthesis | Risk Analysis | Government/Law | Health/Medicine | Child/Nutrition | Chronic Disease/Risk | Environmental Health | Policy/Regulation | Climate/Environment | Food/Agriculture | Science/Technology | Global | North America | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016DNA Evidence: Case Study in Probabilities
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case …
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case in which federal courts at every level discerned “inaccuracies” in the testimony of a leading expert about probabilities associated with the DNA evidence. By embedding these legal materials in background explanations, critical questions, and short problems, the module supports self-study and class discussions that together can elucidate key principles in scientific reasoning and quantitative analysis and that can help students…
Test Performance | Risk Analysis | Government/Law | Health/Medicine | Probability/Bayes | Injuries/Accidents | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Models and Practice
This module is an introduction to models and to their role in regulatory decision-making, and …
This module is an introduction to models and to their role in regulatory decision-making, and is intended for non-scientists from a variety of different backgrounds including law, journalism, public policy, and business. The module covers three main themes: (1) Core lessons on using models for policy making; (2) Key questions on the art and science of modeling including how models differ from other scientific techniques; and (3) Key ideas on using models in policy-making including how…
Mathematical Models | Government/Law | Health/Medicine | Business/Industry | Priority Setting/Ethics | Environmental Health | Policy/Regulation | Climate/Environment | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Conceptual Mapping | Decision Making/Leadership -
Tutorial/PrimerPublication, Teaching Resource 2023Conducting Trial-Based Economic Evaluations Using R: A Tutorial
Trial-based economic evaluations are increasingly conducted to support healthcare decision-making but there are inevitable methodological …
Trial-based economic evaluations are increasingly conducted to support healthcare decision-making but there are inevitable methodological challenges. This tutorial provides step-by-step guidance on how to combine appropriate statistical methods using a ready-to-use R script, and addresses missing data, correlated costs and effects, baseline imbalances, and skewness of costs and/or effects. The authors also provide the theoretical background of these methods, and demonstrate their application through a simulated trial-based economic evaluation.
Evidence Synthesis | Costing Methods | Health/Medicine | Economics/Finance | Graduate | Doctoral | Professional | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Budget Impact Analysis
This video is intended to provide a framework for a budget impact analysis (BIA) which …
This video is intended to provide a framework for a budget impact analysis (BIA) which serves to estimate the cost to a payer of adopting a new intervention over a 1-3 year period and the tools necessary to determine if a BIA is appropriate to undertake. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of Veterans Affairs Health Services Research and Development group…
Costing Methods | Health/Medicine | Business/Industry | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
Lesson/ModuleVideo, Teaching Resource 2018Evidence Synthesis Part II: Quantitative Pooling
This video is intended to provide researchers with an introduction to the second part of conducting …
This video is intended to provide researchers with an introduction to the second part of conducting a meta-analysis: quantitatively pooling. The goal of this meta-analysis is to synthesize multiple published estimates from parameters of interest (such as disease-related mortality or the efficacy of a treatment) into a single input for use in a decision model. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of…
Evidence Synthesis | Mathematical Models | Health/Medicine | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy