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Conducting Trial-Based Economic Evaluations Using R: A Tutorial

2023

Trial-based economic evaluations are increasingly conducted to support healthcare decision-making but there are inevitable methodological challenges. This tutorial provides step-by-step guidance on how to combine appropriate statistical methods using a ready-to-use R script, and addresses missing data, correlated costs and effects, baseline imbalances, and skewness of costs and/or effects. The authors also provide the theoretical background of these methods, and demonstrate their application through a simulated trial-based economic evaluation.  

 

Source:

Ben ÂJ, van Dongen JM, El Alili M et al. Conducting Trial-Based Economic Evaluations Using R: A Tutorial. PharmacoEconomics 2023; 41: 1403-1413. https://doi.org/10.1007/s40273-023-01301-7