Resources Repository
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ArticlePublication 2021New Microsimulation Models to Inform Cervical Cancer Control
Health decision models consider the lifetime natural history of human papillomavirus (HPV) infection and pathogenesis …
Health decision models consider the lifetime natural history of human papillomavirus (HPV) infection and pathogenesis of cervical cancer, and estimate the long-term impact of preventive interventions. We propose a new health decision modeling framework that de-emphasizes previously used cytologic-colposcopic-histologic diagnoses, which are subjective and lack reproducibility, relying instead on HPV type and duration of infection as the major determinants of model transition probabilities. We posit that new model health states and corollary transitions are universal,…
Calibration/Validation | Cost-Effectiveness Analysis | Mathematical Models | Microsimulation | Decision Analysis | Infectious Diseases | Global -
ArticlePublication 2020Expanding Oral Disease Treatment is Cost Effective
This study developed a stochastic microsimulation model of oral health conditions, type-2 diabetes (T2D), T2D-related …
This study developed a stochastic microsimulation model of oral health conditions, type-2 diabetes (T2D), T2D-related microvascular diseases, and CVD, to project the cost-effectiveness of expanding periodontal treatment coverage among patients with T2D and periodontitis. Previous randomized trials found that treating periodontitis improved glycemic control in patients with type 2 diabetes (T2D), thus lowering the risks of developing T2D-related microvascular diseases and cardiovascular disease (CVD). The micro-simulation model parameters were obtained from the nationally representative National…
Calibration/Validation | Cost-Effectiveness Analysis | Mathematical Models | Microsimulation | Chronic Disease/Risk | Health/Medicine | North America | Graduate -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Introduction to Decision Analysis
In this teaching pack on Introduction to Decision Analysis, students are provided a basic introduction to …
In this teaching pack on Introduction to Decision Analysis, students are provided a basic introduction to the field of decision analysis in the context of public health. After differentiating simple "relatively automatic" decisions from those that might require more systematic analysis, students are introduced to the core elements of a decision analysis (e.g., objectives, alternatives, probabilities, and outcomes), and the basic steps of a decision analysis. Materials include an instructor's note, videos, companion slides, a glossary,…
Cost-Effectiveness Analysis | Decision Psychology | Probability/Bayes | Preferences/Values | Decision Analysis | Health/Medicine | Global | College | Graduate | Critical Thinking/Analysis | Quantitative Literacy -
ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Calibration/Validation | Cost-Effectiveness Analysis | Health Outcomes | Mathematical Models | Infectious Diseases | Chronic Disease/Risk | Health Systems | Health/Medicine | Global | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2011Health and Economic Impact of HPV 16/18 Vaccination and Cervical Cancer Screening in Eastern Africa
In this article the authors use epidemiologic data from Kenya, Mozambique, Tanzania, Uganda, and Zimbabwe …
In this article the authors use epidemiologic data from Kenya, Mozambique, Tanzania, Uganda, and Zimbabwe to develop models of HPV-related infection and disease. For each country, they assessed HPV vaccination of girls before age 12 followed by screening with HPV DNA testing once, twice, or three times per lifetime (at ages 35, 40, 45). For women over age 30, they assessed only screening (with HPV DNA testing up to three times per lifetime or VIA…
Calibration/Validation | Cost-Effectiveness Analysis | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Clinical Care | Economics/Finance | Health/Medicine | Science/Technology | Sub-Saharan Africa -
GuidelinesPublication 2011HPV Vaccine Introduction in LMIC's: Guidance on the Use of Cost-Effectiveness Models
This article is a literature review of HPV vaccination models suitable for low-income and middle-income …
This article is a literature review of HPV vaccination models suitable for low-income and middle-income country use to provide information about the feasibility of using such models in a developing country setting. The authors evaluated models in terms of their capacity, requirements, limitations and comparability. Their literature review identified six HPV vaccination models suitable for low-income and middle-income country use and representative of the literature in terms of provenance and model structure. Each model was…
Calibration/Validation | Cost-Effectiveness Analysis | Mathematical Models | Infectious Diseases | Chronic Disease/Risk | Health Systems | Clinical Care | Health/Medicine | Science/Technology | Global -
ReviewPublication 2011Simulation Models of Obesity: A Review of the Literature
Simulation models combine information from a variety of sources to provide a useful tool for …
Simulation models combine information from a variety of sources to provide a useful tool for examining how the effects of obesity unfold over time and impact population health. They can aid in the understanding of the complex interaction of the drivers of diet and activity and their relation to health outcomes. This paper provided an overview of different types of simulation models used to evaluate the potential impact of policies to address the obesity epidemic.…
Calibration/Validation | Cost-Effectiveness Analysis | Mathematical Models | State-Transition | Microsimulation | Decision Analysis | Child/Nutrition | Chronic Disease/Risk | Economics/Finance | Food/Agriculture | Health/Medicine -
ArticlePublication 2010Model Uncertainty in Economic Evaluation of Health Interventions: Rotavirus Vaccination in Vietnam
Motivated by observed discrepancies between 2 published studies on the cost-effectiveness of rotavirus vaccination in …
Motivated by observed discrepancies between 2 published studies on the cost-effectiveness of rotavirus vaccination in Vietnam, the authors' objectives were to illustrate a specific, systematic approach to assessing model (structure and process) uncertainty and to quantify explicitly the contributions of different sources of variation in the outputs of different studies that share the same research question. On the basis of a series of working definitions of key model elements, the authors developed 5 alternative computer…
Calibration/Validation | Cost-Effectiveness Analysis | Mathematical Models | State-Transition | Infectious Diseases | Economics/Finance | Health/Medicine | Asia & Pacific -
BookPublication 2009Encyclopedia of Medical Decision Making
This encyclopedia addresses both prescriptive and descriptive decision making through a conceptual structure consisting of six …
This encyclopedia addresses both prescriptive and descriptive decision making through a conceptual structure consisting of six components of classical decision analysis. It includes articles that have been prepared by more than 200 contributors from around the world. The alphabetical organization of the encyclopedia facilitates access to information. A Reader’s Guide, organized by category of the decisionmaking process includes the following 7 components: Identification of the decision maker - in other words, who must choose. In general, there…
Cost-Effectiveness Analysis | Decision Psychology | Preferences/Values | Costing Methods | Evidence Synthesis | Test Performance | Value of Information | Mathematical Models | Decision Analysis | Benefit-Cost Analysis | Technology Assessment | Health/Medicine