Resources Repository
-
ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Health/Medicine | Risk Analysis | Government/Law | Dynamic Transmission | Decision Analysis | Infectious Diseases | Health Systems | Policy/Regulation | Science/Technology | Global -
OrganizationWeb Portal 2024Institute for Clinical and Economic Review (ICER)
ICER is a non-profit organization that evaluates evidence on a range of topics including the value …
ICER is a non-profit organization that evaluates evidence on a range of topics including the value of medical tests, treatments and delivery system innovations and moves that evidence into action to improve the health care system. To accomplish this goal ICER performs analyses on effectiveness and costs, supports specific programs, and develops reports using innovative methods that make it easier to translate evidence into decisions that can align efforts to use evidence to drive improvements in both…
Value of Information | Health/Medicine | Government/Law | Preferences/Values | Priority Setting/Ethics | Evidence Synthesis | Cost-Effectiveness Analysis | Technology Assessment | Infectious Diseases | Chronic Disease/Risk | Mental Health | Health Systems | Business/Industry | Economics/Finance | Science/Technology | North America | Europe -
OrganizationWeb Portal 2024Society for Risk Analysis
The Society for Risk Analysis (SRA) is a multidisciplinary, interdisciplinary, scholarly, international society that provides …
The Society for Risk Analysis (SRA) is a multidisciplinary, interdisciplinary, scholarly, international society that provides an open forum for all those who are interested in risk analysis. Risk analysis is broadly defined to include risk assessment, characterization, communication, management, and policy. It covers risks of concern to individuals, to public- and private-sector organizations, and to society at a local, regional, national, or global level. The Society includes numerous regional organizations around the world as well as several…
Health/Medicine | Risk Analysis | Government/Law | Injuries/Accidents | Environmental Health | Global Governance | Business/Industry | Climate/Environment | Food/Agriculture | Military/Defense | Science/Technology | Global -
Lesson/ModuleWeb Portal, Teaching Resource 2016Scientific Evidence of Factual Causation
This module examines three scientific areas that provide evidence bearing on causation in the “toxic …
This module examines three scientific areas that provide evidence bearing on causation in the “toxic tort” or environmental disease context: epidemiology, toxicology, and genetics. These scientific disciplines are used in civil lawsuits and in regulatory proceedings in which causation or risk is an issue. The module is appropriate for non-scientist law students as well as others interested in learning the science of toxic tort causation, including practicing attorneys, judges, and public policy and public health…
Health/Medicine | Risk Analysis | Government/Law | Evidence Synthesis | Child/Nutrition | Chronic Disease/Risk | Environmental Health | Policy/Regulation | Climate/Environment | Food/Agriculture | Science/Technology | Global | North America | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016DNA Evidence: Case Study in Probabilities
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case …
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case in which federal courts at every level discerned “inaccuracies” in the testimony of a leading expert about probabilities associated with the DNA evidence. By embedding these legal materials in background explanations, critical questions, and short problems, the module supports self-study and class discussions that together can elucidate key principles in scientific reasoning and quantitative analysis and that can help students…
Health/Medicine | Risk Analysis | Government/Law | Probability/Bayes | Test Performance | Injuries/Accidents | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Drug-Induced Birth Defects
Using the currently topical issue of whether SSRI (Selective Serotonin Reuptake Inhibitor) anti-depressants cause birth …
Using the currently topical issue of whether SSRI (Selective Serotonin Reuptake Inhibitor) anti-depressants cause birth defects, the module aims to provide students with a general understanding of the following: (1) human risk factor causation as determined by epidemiologic methods; (2) the limits of non-human toxicological evidence to the assessment of causality in humans; (3) the importance of pharmacovigilance for all medications; (4) special difficulties in identifying causes of human birth defects; (5) the importance of…
Health/Medicine | Risk Analysis | Government/Law | Health Outcomes | Evidence Synthesis | Child/Nutrition | Chronic Disease/Risk | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016Educational Module: Vaccines
This module engages students in learning about association and causation in the context of vaccines, …
This module engages students in learning about association and causation in the context of vaccines, their side effects, and legal issues that could arise as a result of side effects associated with vaccinations. The module employs five case studies. In the first two case studies, a child receives a vaccination, and students must determine whether an event (vaccination) causes a side effect in the child. In the third case study, a child who has not…
Health/Medicine | Risk Analysis | Government/Law | Health Outcomes | Technology Assessment | Infectious Diseases | Health Systems | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
BookPublication 2014Decision Making in Health and Medicine: Integrating Evidence and Values
Decision making in health care involves consideration of a complex set of diagnostic, therapeutic and …
Decision making in health care involves consideration of a complex set of diagnostic, therapeutic and prognostic uncertainties. Medical therapies have side effects, surgical interventions may lead to complications, and diagnostic tests can produce misleading results. Furthermore, patient values and service costs must be considered. Decisions in clinical and health policy require careful weighing of risks and benefits and are commonly a trade-off of competing objectives: maximizing quality of life vs maximizing life expectancy vs minimizing…
Value of Information | Health/Medicine | Government/Law | Probability/Bayes | Preferences/Values | Costing Methods | Health Outcomes | Test Performance | Mathematical Models | Decision Analysis | Cost-Effectiveness Analysis | Health Systems | Economics/Finance | Global | North America | Europe | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ReviewPublication 2012Applying Decision Science to Managing National Forests
This publication is an example of the application of decision science to the management of …
This publication is an example of the application of decision science to the management of federal public forests, in particular to meet sustainability goals and multiple use regulations. Through three case studies, the authors describe four stages of a decision analytic approach: problem structuring (framing the problem and defining objectives and evaluation criteria), problem analysis (defining alternatives, evaluating likely consequences, identifying key uncertainties, and analyzing tradeoffs), decision point (identifying the preferred alternative), and implementation and monitoring…
Value of Information | Risk Analysis | Government/Law | Decision Analysis | Social Determinants | Environmental Health | Policy/Regulation | Climate/Environment