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Resources Repository
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ArticlePublication 2013Estimated Mortality Impact of Vaccinations 2011–2020 in 73 GAVI Alliance Countries
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted …
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted by the GAVI Alliance and the Bill & Melinda Gates Foundation to estimate the impact of vaccination in 73 countries supported by the GAVI Alliance. The number of deaths averted in persons projected to be vaccinated during 2011–2020 was estimated for ten antigens: hepatitis B, yellow fever, Haemophilus influenzae type B (Hib), Streptococcus pneumoniae, rotavirus, Neisseria meningitidis serogroup A, Japanese…
Microsimulation | Mathematical Models | Dynamic Transmission | State-Transition | Health Outcomes | Health/Medicine | Latin America & Caribbean | Middle East & North Africa | Infectious Diseases | Global Governance | Economics/Finance | Science/Technology | Sub-Saharan Africa | Asia & Pacific -
Resource PackWeb Portal, Teaching Resource 2023Resource Pack: Maternal Health Models and CEA
This resource pack, curated by the Center for Health Decision Science, provides selected examples of …
This resource pack, curated by the Center for Health Decision Science, provides selected examples of modeling approaches used to conduct analyses relevant to maternal and reproductive health. Some papers focus on a particular problem (e.g., screening for prenatal syphilis, comparison of alternative strategies for safe abortion), while others explore strategies for reducing morbidity and mortality from the entire spectrum of pregnancy and childbirth-related complications. Several of the examples model the primary drivers of maternal mortality (e.g.,…
Microsimulation | Mathematical Models | Calibration/Validation | Health/Medicine | Latin America & Caribbean | Middle East & North Africa | Global | Costing Methods | Evidence Synthesis | Cost-Effectiveness Analysis | Maternal/Reproductive Health | Health Systems | Clinical Care | Science/Technology | Sub-Saharan Africa | Asia & Pacific -
ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Mathematical Models | Calibration/Validation | Health Outcomes | Health/Medicine | Latin America & Caribbean | Middle East & North Africa | Global | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Sub-Saharan Africa | Asia & Pacific -
Resource PackPublication, Teaching Resource 2023Resource Pack: Books on Decision Making and Thinking
This resource pack, curated by the Center for Health Decision Science, features books about how …
This resource pack, curated by the Center for Health Decision Science, features books about how we think, learn, and decide. We aim to provide an introduction to some of the core concepts in decision theory and psychology with this collection, and hope that it will stimulate further inquiry. These books are geared to a general audience; the majority are very accessible reads. The collection is broadly divided into three categories. The first is made up of…
Preferences/Values | Probability/Bayes | Decision Psychology | Decision Theory | Health/Medicine | Culture/Society | Global | Business/Industry | Climate/Environment | Economics/Finance | Science/Technology | High School | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Policy Translation -
ArticlePublication 2017Estimated Economic Impact of Vaccinations in 73 LMIC, 2001-2020
This analysis estimates the economic impact likely to be achieved by efforts to vaccinate against 10 …
This analysis estimates the economic impact likely to be achieved by efforts to vaccinate against 10 vaccine-preventable diseases between 2001 and 2020 in 73 low- and middle-income countries largely supported by Gavi, the Vaccine Alliance. The authors used health impact models to estimate the economic impact of achieving forecasted coverages for vaccination against Haemophilus influenzae type b, hepatitis B, human papillomavirus, Japanese encephalitis, measles, Neisseria meningitidis serogroup A, rotavirus, rubella, Streptococcus pneumoniae and yellow fever. In…
Microsimulation | Dynamic Transmission | State-Transition | Health Outcomes | Health/Medicine | Latin America & Caribbean | Middle East & North Africa | Cost-Effectiveness Analysis | Infectious Diseases | Child/Nutrition | Health Systems | Economics/Finance | Sub-Saharan Africa | Asia & Pacific -
ReportPublication 2021What It Means to Be a Science-Literate Citizen in a Digital World
Science literacy is often held up as crucial for avoiding science-related misinformation and enabling more …
Science literacy is often held up as crucial for avoiding science-related misinformation and enabling more informed individual and collective decision-making. But research has not yet examined whether science literacy actually enables this, nor what skills it would need to encompass to do so. This report addresses three questions to outline what it should mean to be science literate in today’s world: (1) How should we conceptualize science literacy? (2) How can we achieve this science…
Preferences/Values | Decision Psychology | Health/Medicine | Education/Labor | Culture/Society | Global | Social Determinants | Energy/Engineering | Science/Technology | North America -
ArticlePublication 2021COVID-19, Fake News, and Vaccines: Should Regulation Be Implemented?
This article analyzes issues concerning the establishment of compulsory vaccination against COVID-19, as well as …
This article analyzes issues concerning the establishment of compulsory vaccination against COVID-19, as well as the role of misinformation as a disincentive – especially when published by health professionals – and citizen acceptance of measures in this regard. Data from different surveys revealed a high degree of hesitation rather than outright opposition to vaccines. The most frequent complaint related to the COVID-19 vaccination was the fear of side effects. Within the Spanish and European legislative…
Preferences/Values | Decision Psychology | Health/Medicine | Education/Labor | Culture/Society | Global | Infectious Diseases | Social Determinants | Policy/Regulation | Government/Law | Science/Technology -
ArticleWeb Portal 2017PLoS Collection: Prevention, Diagnosis and Treatment of Sexually Transmitted Infections
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted …
Globally, the World Health Organization (WHO) estimates that more than one million new sexually transmitted infections (STIs) occur each day, incurring a very substantial burden of morbidity, mortality and additional infections. The pathogens responsible include bacteria, parasites and viruses, and intensive research is needed to address the substantial barriers to diagnosis and treatment of STIs, and the behavioral challenges of prevention. This PLOS collection, published in collaboration with WHO, focuses on global policy and systems…
Priority Setting/Ethics | Mathematical Models | Dynamic Transmission | Health/Medicine | Latin America & Caribbean | Middle East & North Africa | Costing Methods | Cost-Effectiveness Analysis | Infectious Diseases | Health Systems | Economics/Finance | Sub-Saharan Africa | Asia & Pacific -
ArticlePublication 2010Health and Economic Impact of Rotavirus Vaccination in GAVI-Eligible Countries
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately …
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately borne by children in low-income countries. Motivated by the global recommendation by the WHO that all countries include infant rotavirus vaccination in their national immunization programs, the objective of this analysis was to provide information on the expected health, economic and financial consequences of rotavirus vaccines in the 72 GAVI support-eligible countries. The authors synthesized population-level data from various sources (primarily from…
Mathematical Models | State-Transition | Health Outcomes | Health/Medicine | Latin America & Caribbean | Middle East & North Africa | Cost-Effectiveness Analysis | Infectious Diseases | Child/Nutrition | Economics/Finance | Sub-Saharan Africa | Asia & Pacific