Resources Repository
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Resource PackPublication, Teaching Resource 2018Resource Pack: Model Calibration and Validation
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to …
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to empirical calibration and validation methods for mathematical models used in health decision analysis. Included are a selection of overviews, guidelines, tutorials, and applications. Given the complexity of diseases and variation in data quality, there are invariably a number of parameters that are unobserved or cannot be estimated directly but can be inferred through the process of model calibration. Model calibration…
Dynamic Transmission | Mathematical Models | State-Transition | Microsimulation | Calibration/Validation | Dynamic Simulation | Health/Medicine -
Resource PackPublication, Teaching Resource 2018Resource Pack: Models for Health Decision Science
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to …
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to mathematical models used in health decision science (e.g., microsimulation, dynamic transmission, agent-based, etc.). Resources include overviews, guidelines, tutorials, and applications relevant to a broad range of clinical and public health topics. A decision analytic approach relies on the use of a mathematical model to formally structure the components of the decision over time. Models are particularly useful when multiple data sources…
Dynamic Transmission | Mathematical Models | State-Transition | Microsimulation | Dynamic Simulation | Climate/Environment | Economics/Finance | Health/Medicine | Science/Technology -
ReportPublication 2013Decision and Simulation Modeling Alongside Systematic Reviews
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks …
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The chapter discusses the role of decision analysis and decision-analytic models in health care, specifically within the context of the current emphasis on evidence-based medicine and the proliferation of systematic reviews. It describes the types of model available…
Dynamic Transmission | Evidence Synthesis | State-Transition | Microsimulation | Dynamic Simulation | Health Systems | Clinical Care | Health/Medicine -
ArticlePublication 2018Equity Impact Vaccines May Have on Averting Deaths and Medical Impoverishment
In this analysis, authors estimated the number of deaths averted and the number of cases …
In this analysis, authors estimated the number of deaths averted and the number of cases of medical impoverishment averted of ten antigens and their corresponding vaccines across income quintiles for forty-one low- and middle-income countries. The study found that vaccines administered between 2016 and 2030 would prevent 36 million deaths. Vaccines will have the greatest impact on reducing cases of poverty caused by hepatitis B, helping an estimated 14 million people avoid medical impoverishment. An…
Priority Setting/Ethics | Costing Methods | Health Outcomes | Mathematical Models | Cost-Effectiveness Analysis | Infectious Diseases | Child/Nutrition | Global Governance | Economics/Finance | Health/Medicine | Science/Technology | Sub-Saharan Africa | Middle East & North Africa | Asia & Pacific -
ArticlePublication 2018Trading Bankruptcy for Health: A Discrete-Choice Experiment
This article in Value in Health evaluates the importance of improved health as compared to …
This article in Value in Health evaluates the importance of improved health as compared to improved financial risk protection in the general United States population. Using a discrete-choice experiment, it finds that 31.3% of the population values cure at all costs, and 8.5% of the population use financial solvency to dominate medical decision making. This study shares insight to the US population values and trade-offs between health outcomes and financial health, and highlights the difficult…
Priority Setting/Ethics | Preferences/Values | Health Outcomes | Health Systems | Culture/Society | Economics/Finance | Health/Medicine | North America -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Population Health Outcomes
In this teaching pack on Population Health Outcomes, students learn how to describe outcomes at a …
In this teaching pack on Population Health Outcomes, students learn how to describe outcomes at a population level using quality adjusted life years (QALYs), including how to calculate QALYs, the assumptions underlying them, how to derive QALYs using indirect utility measures, and what are some of the ethical criticisms of QALYs. Materials include an instructor’s note, videos, companion slides, a glossary, an annotated bibliography, and sample exercises. Learning Objectives Define Quality-Adjusted Life Years (QALYs)…
Priority Setting/Ethics | Preferences/Values | Health Outcomes | Injuries/Accidents | Health/Medicine | College | Graduate | Doctoral -
ArticleWeb Portal 2017PLOS Collection: Economic Efficiency of HIV Services
In order to maximize the value for money for HIV services and increase efficiency without …
In order to maximize the value for money for HIV services and increase efficiency without sacrificing quality, robust and up-to-date data on costs, efficiency and its determinants are needed. This PLOS collection, Economic Efficiency of HIV Services, presents recent, high-quality evidence from low- and middle-income countries on costs and technical efficiency of HIV services and their determinants. These data contribute to the current discussion on optimizing resources for HIV services and can provide programmatic guidance for…
Priority Setting/Ethics | Costing Methods | Cost-Effectiveness Analysis | Operations Research | Infectious Diseases | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Dynamic Transmission | Decision Analysis | Risk Analysis | Infectious Diseases | Health Systems | Policy/Regulation | Government/Law | Health/Medicine | Science/Technology | Global -
Online LearningVideo, Teaching Resource 2017Forum. The Opioid Crisis: A Governors Roundtable
Opioid overdoses claim the lives of 91 Americans every day, according to the Centers for …
Opioid overdoses claim the lives of 91 Americans every day, according to the Centers for Disease Control and Prevention. This Forum - The Opioid Crisis: A Governors Roundtable, is part of the series, Policy Controversies, and was presented jointly with PRI’s The World & WGBH News. In this multimedia forum, four former governors offered candid insights into how government policy can help, exploring what works and what doesn’t. They spoke about experiences within their own…
Priority Setting/Ethics | Health Outcomes | Chronic Disease/Risk | Mental Health | Social Determinants | Health Systems | Policy/Regulation | Economics/Finance | Government/Law | Health/Medicine | North America | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Decision Making/Leadership | Policy Translation