Resources Repository
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ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Risk Analysis | Dynamic Transmission | Decision Analysis | Infectious Diseases | Health Systems | Policy/Regulation | Government/Law | Health/Medicine | Science/Technology | Global -
Resource PortalWeb Portal, Teaching Resource 2024Decision Sciences Institute
The Decision Sciences Institute (DSI) was founded in 1968 as the American Institute for the …
The Decision Sciences Institute (DSI) was founded in 1968 as the American Institute for the Decision Sciences (renamed to the Decision Science Institute in 1986). DSI is an independent non-profit organization with a mission to enrich the discipline of decision sciences and improve educational programs and instruction in decision sciences. DSI conducts annual meetings at the national and the regional levels, and produces a monthly news publication called “Decision Line” as well as two journals,…
Operations Research | Decision Analysis | Business/Industry | Climate/Environment | Health/Medicine | Global | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2017OR-Library
The OR-Library serves as an educator tool by providing a collection of test data sets …
The OR-Library serves as an educator tool by providing a collection of test data sets for a variety of problems in operations research (OR). They were developed and used by J E Beasley and he has made them available for use by any students and teachers interested in OR subject provided he is acknowledged and identified as their author. J E Beasley completed his PhD in Management Science at Imperial College, London, was a faculty member…
Operations Research | Business/Industry | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
Tutorial/PrimerPublication, Teaching Resource 2017Guide to Regulatory Impact Analysis
Regulatory impact analyses (RIAs) weigh the benefits of regulations against the burdens they impose and …
Regulatory impact analyses (RIAs) weigh the benefits of regulations against the burdens they impose and are invaluable tools for informing decision makers. The Consumer’s Guide to Regulatory Impact Analysis: Ten Tips for Being an Informed Policymaker offers 10 tips for non-specialist policymakers and interested stakeholders who will be reading RIAs as consumers.
Risk Analysis | Benefit-Cost Analysis | Government/Law | Global -
Tools/ModelsPublication, Teaching Resource 2017Publicly Available Software Tools for Decision-Makers During an Emergent Epidemic
Epidemics and emerging infectious diseases are becoming an increasing threat to global populations-challenging public health …
Epidemics and emerging infectious diseases are becoming an increasing threat to global populations-challenging public health practitioners, decision makers and researchers to plan, prepare, identify and respond to outbreaks in near real-timeframes. The aim of this research is to evaluate the range of public domain and freely available software epidemic modelling tools. Twenty freely utilizable software tools underwent assessment of software usability, utility and key functionalities. Stochastic and agent based tools were found to be highly…
Dynamic Simulation | Mathematical Models | Dynamic Transmission | Infectious Diseases | Health Systems | Climate/Environment | Health/Medicine | Science/Technology | Global | Graduate | Doctoral | Professional | Quantitative Literacy -
ArticlePublication 2017Using Data-Driven Agent-Based Models to Forecast Emerging Infectious Diseases
This paper describes an agent-based model framework developed to forecast the 2014-15 Ebola epidemic, which …
This paper describes an agent-based model framework developed to forecast the 2014-15 Ebola epidemic, which was subsequently used in the Ebola forecasting challenge. Producing timely and reliable forecasts for an epidemic of an emerging infectious disease is a challenge. Epidemiologists and policy makers have to deal with poor data quality, limited understanding of the disease dynamics, a rapidly changing social environment and the uncertainty around the effects of various interventions in place. In this setting,…
Dynamic Simulation | Microsimulation | Calibration/Validation | Infectious Diseases | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2017Designing an Optimal HIV Programme for South Africa
This 2017 study compares the traditional and a novel method of comparing cost-effectiveness interventions in …
This 2017 study compares the traditional and a novel method of comparing cost-effectiveness interventions in the context of HIV in South Africa, using a modeling approach. The authors argue that the assumptions of a) independence of interventions, and b) linear scale-up effects do not hold because South Africa has a large domestically funded HIV program with highly saturated coverage levels. The authors therefore aim to better allocate resources for HIV interventions in South Africa when…
Operations Research | Priority Setting/Ethics | Mathematical Models | Cost-Effectiveness Analysis | Infectious Diseases | Health Systems | Economics/Finance | Health/Medicine | Sub-Saharan Africa -
ArticlePublication 2017Policy Makers, the International Community and the Population: Case Study on HIV/AIDS
A four-period game is developed between a policy maker, the international community, and the population. …
A four-period game is developed between a policy maker, the international community, and the population. This research supplements, through implementing strategic interaction, earlier research analyzing "one player at a time." The first two players distribute funds between preventing and treating diseases. The population reacts by degree of risky behavior which may cause no disease, disease contraction, recovery, sickness/death. More funds to prevention implies less disease contraction but higher death rate given disease contraction. The cost…
Decision Psychology | Priority Setting/Ethics | Mathematical Models | Infectious Diseases | Health Systems | Global Governance | Economics/Finance | Government/Law | Health/Medicine | Global -
ArticlePublication 2017Likelihood Approach for Calibration of Stochastic Epidemic Models
Stochastic transmission dynamic models are especially useful for studying the early emergence of novel pathogens …
Stochastic transmission dynamic models are especially useful for studying the early emergence of novel pathogens given the importance of chance events when the number of infectious individuals is small. However, methods for parameter estimation and prediction for these types of stochastic models remain limited. This paper describes a calibration and prediction framework for stochastic compartmental transmission models of epidemics. The proposed method applies a linear noise approximation to describe the size of the fluctuations, and…
Dynamic Simulation | Dynamic Transmission | Calibration/Validation | Infectious Diseases | Health Systems | Health/Medicine | Global