Resources Repository
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ArticlePublication 2015Population Health Model (POHEM): An Overview
This paper provides an overview of the rationale, methodology and applications of the Population Health …
This paper provides an overview of the rationale, methodology and applications of the Population Health Model (POHEM). POHEM is a health microsimulation model, developed at Statistics Canada in the early 1990s. The authors describe that POHEM draws together rich multivariate data from a wide range of sources to simulate the lifecycle of the Canadian population, specifically focusing on aspects of health. The model dynamically simulates individuals’ disease states, risk factors, and health determinants, in order…
Mathematical Models | Calibration/Validation | Costing Methods | Evidence Synthesis | Microsimulation | Chronic Disease/Risk | Health Systems | Policy/Regulation | Clinical Care | Economics/Finance | Health/Medicine | North America -
BookPublication 2016Foundations of Decision Analysis
This book is described by the authors as emerging from what they have learned by …
This book is described by the authors as emerging from what they have learned by "teaching decision analysis to thousands of people in the United States and around the world in university classes and special professional educational programs". The early chapters and certain later chapters are written to be accessible to a general audience. Chapters 1 through 17 introduce the foundations of decision analysis without requiring significant mathematical sophistication. Chapter 26 discusses multi-attribute decision problems…
Decision Psychology | Decision Theory | Probability/Bayes | Decision Analysis | Operations Research | Business/Industry | Economics/Finance | Energy/Engineering | Government/Law | Health/Medicine | Military/Defense | Global -
ReportPublication 2015Modeling to Improve Policy Decisions in the Americas: Noncommunicable Diseases
In the Region of the Americas, noncommunicable diseases (NCDs) are a clear threat not only …
In the Region of the Americas, noncommunicable diseases (NCDs) are a clear threat not only to human health, but also to a country’s economic development and growth. The evidence on both of these counts is compelling. In 2012, cardiovascular disease, diabetes, cancers, chronic respiratory conditions including asthma, and other NCDs were the cause of 4.5 million deaths in the Americas. Of that total number, 1.5 million of them were premature, occurring among people aged 30-69…
Mathematical Models | State-Transition | Priority Setting/Ethics | Costing Methods | Microsimulation | Decision Analysis | Cost-Effectiveness Analysis | Chronic Disease/Risk | Mental Health | Health/Medicine | Latin America & Caribbean -
ArticlePublication 2014Cost-Effectiveness of Female HPV Vaccination in 179 Countries: A PRIME Modelling Study
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), …
The authors present a simple generic model, Papillomavirus Rapid Interface for Modelling and Economics (PRIME), used to assess cost-effectiveness and health effects of vaccination of girls against HPV before sexual debut in terms of burden of cervical cancer and mortality. The PRIME models incidence according to proposed vaccine efficacy against HPV 16/18, vaccine coverage, cervical cancer incidence and mortality, and HPV type distribution. It assumes lifelong vaccine protection and no changes to other screening programs…
Mathematical Models | Calibration/Validation | Health Outcomes | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Health/Medicine | Global | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
Lesson/ModuleWeb Portal, Teaching Resource 2014Life Saving Maths: How Does Vaccination Work?
This learning module explores decision-making in vaccinations, and unpacks how epidemics spread through herd immunity. …
This learning module explores decision-making in vaccinations, and unpacks how epidemics spread through herd immunity. Through video clips, Dr. Julia Gog and Dr. Andrew Conlan explain simple mathematical models for infectious disease to illustrate the importance of immunization. Related resources, such as activities, worksheets, and presentations, are available to help students investigate the effects of vaccination. These activities are recommended to be used together but can also be used independently. They are aimed at a…
Mathematical Models | Dynamic Transmission | Infectious Diseases | Health/Medicine | Science/Technology | Global | High School | Critical Thinking/Analysis | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2014Maths and Our Health
This learning module provides teaching packs to explore biomedical real-world applications of probability and statistics …
This learning module provides teaching packs to explore biomedical real-world applications of probability and statistics in decision-making. Each pack provides videos and supplemental materials, including presentations, worksheets, and games. Topics include: “Eating Bacon Sandwiches is Bad for You!” Evaluating Risk Epidemics: Modelling with Mathematics Life Saving Maths: How Does Vaccination Work? The Economics of Health: How Do We Decide? The Test is Positive: But What Are the Odds It’s Wrong?
Mathematical Models | Decision Theory | Test Performance | Decision Analysis | Infectious Diseases | Child/Nutrition | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Science/Technology | Global | Middle School | High School | Critical Thinking/Analysis | Decision Making/Leadership | Quantitative Literacy -
ReviewPublication 2014Markov Modeling & Discrete Event Simulation in Health Care: Systematic Comparison
This review assesses whether the use of Markov modeling (MM) or discrete event simulation (DES) …
This review assesses whether the use of Markov modeling (MM) or discrete event simulation (DES) for cost-effectiveness analysis (CEA) may alter healthcare resource allocation decisions. A systematic literature search and review of empirical and non-empirical studies comparing MM and DES techniques used in the CEA of healthcare technologies was conducted. The primary advantages described for DES over MM were the ability to model queuing for limited resources, capture individual patient histories, accommodate complexity and uncertainty,…
Mathematical Models | State-Transition | Microsimulation | Health Systems | Clinical Care | Health/Medicine -
ArticlePublication 2014Indemics: Interactive Computing Framework for Data Intensive Epidemic Modeling
The design and prototype implementation of Indemics (Interactive EpidemicSimulation) is described, a modeling environment utilizing …
The design and prototype implementation of Indemics (Interactive EpidemicSimulation) is described, a modeling environment utilizing high-performance computing technologies for supporting complex epidemic simulations. Indemics can support policy analysts and epidemiologists interested in planning and control of pandemics. Indemics goes beyond traditional epidemic simulations by providing a way to represent and analyze policy-based as well as individual-based adaptive interventions. Users can also stop the simulation at any point, assess the state of the simulated system, and…
Mathematical Models | Dynamic Transmission | Infectious Diseases | Health/Medicine | Science/Technology -
GuidelinesPublication 2012Model Transparency and Validation: A Report of the ISPOR-SMDM Modeling Task Force-7
This paper discusses how to improve trust in the use of health care models through …
This paper discusses how to improve trust in the use of health care models through validation and transparency. Validation involves face validity (wherein experts evaluate model structure, data sources, assumptions, and results), verification or internal validity (check accuracy of coding), cross validity (comparison of results with other models analyzing same problem), external validity (comparing model results to real-world results), and predictive validity (comparing model results with prospectively observed events). Recommendations are provided for nontechnical description…
Mathematical Models | Calibration/Validation | Costing Methods | Health Outcomes | Health/Medicine