Resources Repository
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ReviewPublication 2018Equity Considerations in CEA: Rotavirus Vaccine in LMIC's
The authors used a systematic review of the literature to identify economic evaluations of rotavirus …
The authors used a systematic review of the literature to identify economic evaluations of rotavirus vaccine in LMICs and assess the extent to which equity was considered in the objectives, analysis, and results. They used equity-related indicators provided in the Guidance on Priority Setting in Health Care (GPS-Health) checklist criteria resulting in 18 unique indicators tracked. The authors found that some articles incorporated the indicators in their model inputs (20%) while the majority (80%) presented…
Global | Evidence Synthesis | Cost-Effectiveness Analysis | Infectious Diseases | Social Determinants | Health/Medicine -
ReviewPublication 2018Primary & Secondary Prevention Interventions for Cardiovascular Disease in LMIC's
Motivated by the need for evidence on cardiovascular disease (CVD) interventions offering good value for …
Motivated by the need for evidence on cardiovascular disease (CVD) interventions offering good value for the money, the authors conducted a systematic review, including 50 studies. Included studies were those that reported full economic evaluations of individual and population-based interventions (pharmacologic and non-pharmacologic), for primary and secondary prevention of CVD among adults in LMIC. The majority of the studies were of modelled evaluations, with significant heterogeneity in methods. Most of the economic evaluations evaluated were…
Global | Costing Methods | Health Outcomes | Evidence Synthesis | Chronic Disease/Risk | Health/Medicine -
ArticlePublication 2018Resource Allocation in Decision Support Frameworks
Multi-criteria decision-making frameworks expand on typical decision analyses (cost-effectiveness and cost-benefit) by explicitly incorporating value …
Multi-criteria decision-making frameworks expand on typical decision analyses (cost-effectiveness and cost-benefit) by explicitly incorporating value tradeoffs from decision makers and summarizing the performance of investment options. This is done across all chosen dimensions of value, based on the weights provided by the decision makers, but comes at a cost. Currently there is no widely accepted method to suggest how to determine a budget constraint using multi-attribute models or to measure willingness to pay for incremental…
Global | Priority Setting/Ethics | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Health Systems | Health/Medicine -
ReviewPublication 2018Incorporating MCDA into HTA: A Focus on Lower Income Settings
The authors present key challenges, both methodological and practical against using multicriteria decision analysis (MCDA) …
The authors present key challenges, both methodological and practical against using multicriteria decision analysis (MCDA) in health technology assessment (HTA) as well as solutions to these challenges. They showcase lessons learned from previous applications of MCDS to HTA, including design, criteria of models, approaches for estimating costs and challenges with various approaches. By showing efforts that have succeeded in overcoming these challenges in lower and middle income-countries, they show how MCDA has the potential to…
Global | Priority Setting/Ethics | Health Systems | Health/Medicine -
ReviewPublication 2018Reflective Multicriteria for Healthcare Decision-Making? The EVIDEM Journey
The authors discuss a framework for mulicriteria decision making for healthcare decision making that was …
The authors discuss a framework for mulicriteria decision making for healthcare decision making that was created and used by the EVIDEM Collaboration between 2006 and 2017. This framework originally incorporated healthcare ethics, evidenced-based medicine, health economics, health technology assessment and multicriteria approaches to decision making. The authors present this modified 10th edition framework, which builds on these by enhancing the following 4 areas: universal healthcare, values and ethics, evidence-based interventions, and process transformation. The framework…
Global | Priority Setting/Ethics | Health Systems | Health/Medicine -
ArticlePublication 2018Examining Evaluation Methods for Health Equity Policies
This article reviews diverse methods for evaluating public policies that address social determinants of health …
This article reviews diverse methods for evaluating public policies that address social determinants of health equity. Understanding approaches to evaluating public policies is essential in strengthening the evidence base that informs policy change. Examining 50 studies in the article, the authors find that most studies evaluating policies for health equity outcomes use observational research designs and regression techniques to analyze impact. Furthermore, the studies reviewed primarily relied on secondary data, and nearly three out of…
Global | Health Outcomes | Evidence Synthesis | Social Determinants | Global Governance | Government/Law -
ReviewPublication 2018Patient Variability Seldom Assessed in Cost-Effectiveness Studies
This article in Medical Decision Making reviews 200 articles published in 2014 to determine whether …
This article in Medical Decision Making reviews 200 articles published in 2014 to determine whether each cost-effectiveness analysis (CEA) study reported subgroup results and collected data on the defining characteristics of these subgroups. Since estimates can vary across patient subgroups when characteristics are influenced by preferences, outcome risks, treatment effectiveness, life expectancy, or associated costs it can be important to track and report these differences. The authors identified whether any of the CEA subgroup results…
Global | Preferences/Values | Cost-Effectiveness Analysis | Social Determinants | Health Systems | Policy/Regulation | Health/Medicine -
ArticlePublication 2017Costing of National STI Program Implementation, 2016-2021
In 2016 the World Health Assembly adopted the Global Strategy on Sexually Transmitted Infections (STI) …
In 2016 the World Health Assembly adopted the Global Strategy on Sexually Transmitted Infections (STI) 2016–2021 aiming to reduce curable STIs by 90% by 2030. This analysis costed scaling-up priority interventions to achieve coverage targets. Strategy-targeted declines in Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum and Trichomonas vaginalis were applied to WHO-estimated regional burdens at 2012 levels. Case management was costed for the curable STIs, symptomatic Herpes Simplex Virus 2 (HSV-2), and non-STI vaginal syndromes, with incrementally expanding diagnoses. Service…
Global | Costing Methods | Evidence Synthesis | Infectious Diseases | Clinical Care | Economics/Finance | Health/Medicine -
ArticlePublication 2017Estimating the Fitness Cost and Benefit of Cefixime Resistance in Neisseria Gonorrhoeae
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more …
Gonorrhoea is one of the most common bacterial sexually transmitted infections in England, and more than half of annual infections occur in men who have sex with men (MSM). As the bacterium has developed resistance to each first-line antibiotic in turn, an improved understanding is needed of fitness benefits and costs of antibiotic resistance to inform control policy and planning. The authors developed a stochastic compartmental model representing the natural history and transmission of cefixime-sensitive…
Global | Dynamic Transmission | Decision Analysis | Risk Analysis | Infectious Diseases | Health Systems | Policy/Regulation | Government/Law | Health/Medicine | Science/Technology