Resources Repository
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GuidelinesPublication 2012Modeling Using Discrete Event Simulation: A Report of the ISPOR-SMDM Modeling Task Force-4
This paper reports on consensus-based guidelines on the application of DES in a health care …
This paper reports on consensus-based guidelines on the application of DES in a health care setting, covering the range of issues to which DES can be applied. Discrete event simulation (DES) is a form of computer-based modeling that provides an intuitive and flexible approach to representing complex systems. The article works through the different stages of the modeling process: structural development, parameter estimation, model implementation, model analysis, and representation and reporting. Recommendations are made for…
Calibration/Validation | Evidence Synthesis | Mathematical Models | Dynamic Simulation | Health/Medicine -
GuidelinesPublication 2012Modeling Good Research Practices - Overview: A Report of the ISPOR-SMDM Modeling Task Force-1
This paper provides an overview of the work of the joint Task Force between the …
This paper provides an overview of the work of the joint Task Force between the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) and the Society for Medical Decision Making (SMDM), provides the overarching recommendations, and discusses future work that is needed. The audience for these papers includes anyone who build models, stakeholders who utilize their results, and those concerned with the use of models to support decision making. This article is part 1 of…
Calibration/Validation | Costing Methods | Health Outcomes | Value of Information | Mathematical Models | State-Transition | Dynamic Transmission | Microsimulation | Dynamic Simulation | Decision Analysis | Infectious Diseases | Health/Medicine -
GuidelinesPublication 2012Model Parameter Estimation and Uncertainty Analysis: A Report of the ISPOR-SMDM Modeling Task Force-6
This paper discusses methods for the reporting of uncertainty, both in terms of deterministic sensitivity …
This paper discusses methods for the reporting of uncertainty, both in terms of deterministic sensitivity analysis techniques and probabilistic methods. Stochastic (first-order) uncertainty is distinguished from both parameter (second-order) uncertainty and from heterogeneity, with structural uncertainty relating to the model itself forming another level of uncertainty. The article describes the process of estimating model inputs, whether these are point estimates or distributions. It also explores the link between parameter uncertainty, decision uncertainty, and value-of-information analysis.…
Calibration/Validation | Value of Information | Mathematical Models | Health/Medicine -
ReviewPublication 2012From Efficacy to Equity: Literature Review
Resource allocation is a challenging issue faced by health policy decision makers requiring careful consideration …
Resource allocation is a challenging issue faced by health policy decision makers requiring careful consideration of many factors. The aim of this study was to analyse the peer-reviewed literature to identify criteria reported in empirical studies that involved healthcare decisionmakers and in studies describing multicriteria tools.
Priority Setting/Ethics | Social Determinants | Health/Medicine -
ArticlePublication 2012Expert Elicitation of VSL
This article uses expert elicitation to address the monetary value of avoided premature mortality, which …
This article uses expert elicitation to address the monetary value of avoided premature mortality, which typically dominates the quantified benefits of air pollution regulations. Formal expert elicitation methods are one means of characterizing associated uncertainties. The authors undertake a pilot study that elicits quantitative probabilistic judgments of uncertainties in value per statistical life (VSL) estimates for use in an air pollution context. The two-stage elicitation addresses uncertainties in both a base case VSL for a…
Preferences/Values | Benefit-Cost Analysis | Policy/Regulation | Climate/Environment | College | Graduate | Critical Thinking/Analysis -
ArticlePublication 2012Value of Family Planning for Improving Maternal Health in Rural Afghanistan
This article, published in the Afghanistan Journal of Public Health, uses a model designed to …
This article, published in the Afghanistan Journal of Public Health, uses a model designed to simulate the natural history of pregnancy and associated maternal mortality and morbidity contextualized to Afghanistan to assess the cost-effectiveness of family planning in the rural Maywand district of Kandahar. Using total fertility rate, pregnancy-related complications, maternal mortality ratio, lifetime risk of maternal death, and proportionate mortality ratio as outcomes, the model finds that increasing family planning from 8% to 30-50% could…
Cost-Effectiveness Analysis | Health Outcomes | Maternal/Reproductive Health | Policy/Regulation | Health/Medicine | Asia & Pacific -
ArticlePublication 2012Health and Economic Outcomes of Interventions to Reduce Pregnancy-Related Mortality in Nigeria
This paper examines the cost-effectiveness and impact of individual and integrated packages of interventions aimed …
This paper examines the cost-effectiveness and impact of individual and integrated packages of interventions aimed to reduce maternal mortality in Nigeria, a country with extremely high maternal mortality rates. Using a previously validated model adapted to the Nigerian context, the study finds that an increase of access to family planning is the most effective individual strategy, which not only reduces pregnancy-related mortality but also proves to be economically efficient. However, relying solely on family planning…
Cost-Effectiveness Analysis | Health Outcomes | State-Transition | Maternal/Reproductive Health | Health Systems | Policy/Regulation | Economics/Finance | Health/Medicine | Sub-Saharan Africa -
ReportPublication 2012Mortality Risks in Environment, Health and Transport
This report presents a major meta-analysis of value of a statistical life (VSL) estimates derived …
This report presents a major meta-analysis of value of a statistical life (VSL) estimates derived from surveys around the world. The analysis seeks to explain the differences in the estimates, for example across countries. Differences in incomes and the magnitude of the risk reduction were found to be the factors having the strongest impact, but numerous other policy-relevant factors are also important. The report also presents advice on how VSL estimates can be best used…
Preferences/Values | Benefit-Cost Analysis | Policy/Regulation | Climate/Environment | College | Graduate | Critical Thinking/Analysis -
ArticlePublication 2011Cost-Effectiveness of Psychotherapy for Cluster C Personality Disorders
This article, published in the Journal of Clinical Psychiatry, describes a probabilistic Markov cohort model …
This article, published in the Journal of Clinical Psychiatry, describes a probabilistic Markov cohort model that compares the cost-effectiveness of five treatment modalities (long-term outpatient psychotherapy, short-term and long-term day hospital psychotherapy, and short-term and long-term inpatient psychotherapy) for patients with cluster C personality disorders. The analyses are conducted from the societal and payer perspectives. Patient-level data comes from 466 patients with cluster C personality disorders who were admitted to 6 specialist centers of psychotherapy…
Cost-Effectiveness Analysis | State-Transition | Mental Health | Health/Medicine | Europe