Resources Repository
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ReviewPublication 2017Validation and Calibration of Structural Models that Combine Information from Multiple Sources
This is a review of calibration and validation methods in mathematical modeling. Such models that …
This is a review of calibration and validation methods in mathematical modeling. Such models that attempt to capture structural relationships between their components and combine information from multiple sources are increasingly used in medicine. The authors provide an overview of methods for model validation and calibration and survey studies comparing alternative approaches. Model validation entails a confrontation of models with data, background knowledge, and other models, and can inform judgments about model credibility. Calibration involves…
Calibration/Validation | Health/Medicine | Mathematical Models -
ArticlePublication 2017Likelihood Approach for Calibration of Stochastic Epidemic Models
Stochastic transmission dynamic models are especially useful for studying the early emergence of novel pathogens …
Stochastic transmission dynamic models are especially useful for studying the early emergence of novel pathogens given the importance of chance events when the number of infectious individuals is small. However, methods for parameter estimation and prediction for these types of stochastic models remain limited. This paper describes a calibration and prediction framework for stochastic compartmental transmission models of epidemics. The proposed method applies a linear noise approximation to describe the size of the fluctuations, and…
Calibration/Validation | Health/Medicine | Dynamic Transmission | Dynamic Simulation | Infectious Diseases | Health Systems | Global -
Teaching PackWeb Portal, Teaching Resource 2018Teaching Pack: Teaching Prototypes for Decision Analysis
These videos, developed by Professor Myriam Hunink during an immersion residency at the Center for …
These videos, developed by Professor Myriam Hunink during an immersion residency at the Center for Health Decision Science (CHDS) Media Hub, reflect experiments to augment brick and mortar teaching with multimedia materials that emphasize visualization of basic concepts. The first video introduces decision making under uncertainty, and illustrates the use of probability and odds to quantitatively express uncertainty. The second and third videos introduce probability revision visually and analytically, showing how an initial probability is…
Probability/Bayes | Health/Medicine | Test Performance | Value of Information | Chronic Disease/Risk | Health Systems | North America | Europe | High School | College | Graduate | Doctoral | Critical Thinking/Analysis | Graphics/Visualization | Quantitative Literacy -
OrganizationWeb Portal 2024International Society for Bayesian Analysis (ISBA)
The International Society for Bayesian Analysis (ISBA) was founded in 1992 to promote the development …
The International Society for Bayesian Analysis (ISBA) was founded in 1992 to promote the development and application of Bayesian analysis. By sponsoring and organizing meetings, publishing the electronic journal Bayesian Analysis, and other activities, ISBA provides an international community for those interested in Bayesian analysis and its applications, and includes interest sections on topics such as biostatistics/pharmaceuticals, computation, economics/finance/business, education research/practice, environmental sciences, industrial statistics, nonparametrics and objective Bayes. Bayesian Analysis is the electronic journal…
Probability/Bayes | Health/Medicine | Decision Theory | Business/Industry | Climate/Environment | Education/Labor | Science/Technology | Global -
Resource PackWeb Portal, Teaching Resource 2023Resource Pack: Decision Science Textbooks
This resource pack, curated by the Center for Health Decision Science, features introductory textbooks in …
This resource pack, curated by the Center for Health Decision Science, features introductory textbooks in decision analysis. These textbooks are mainly aimed at health professional schools but also public policy, law, business and engineering. Each textbook is accompanied by a downloadable PDF document with information on each chapter. The textbooks are broadly organized into three groups. The first group contains books on general decision analysis. They inform the reader on overarching decision analytic topics, such…
Probability/Bayes | Health/Medicine | Decision Theory | Preferences/Values | Costing Methods | Test Performance | Value of Information | Mathematical Models | Decision Analysis | Cost-Effectiveness Analysis | Economics/Finance | Science/Technology | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Conceptual Mapping | Decision Making/Leadership | Quantitative Literacy -
Resource PortalWeb Portal, Teaching Resource 2024MIDAS
MIDAS is a collaborative network of research scientists who use computational, statistical and mathematical models …
MIDAS is a collaborative network of research scientists who use computational, statistical and mathematical models to understand infectious disease dynamics and thereby assist the nation to prepare for, detect and respond to infectious disease threats. Midas focuses on research topics such as: Dynamics of emergence and spread of pathogens; Identification and surveillance of infectious diseases; Effectiveness and consequences of intervention strategies; Host/pathogen interactions; Ecological, climatic, economic and evolutionary dimensions of infectious diseases; The roles of behavior and behavioral adaptation in…
Calibration/Validation | Health/Medicine | Mathematical Models | Dynamic Transmission | Dynamic Simulation | Risk Analysis | Cost-Effectiveness Analysis | Technology Assessment | Infectious Diseases | Health Systems | Policy/Regulation | Climate/Environment | Science/Technology | Global | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Conceptual Mapping | Quantitative Literacy -
Online LearningVideo, Teaching Resource 2023Khan Videos: Conditional Probability
These three videos, produced by Khan Academy, focus on conditional probability. Conditional probability with Bayes' …
These three videos, produced by Khan Academy, focus on conditional probability. Conditional probability with Bayes' Theorem (~5 min). Created by Brit Cruise, this video presents conditional probability visually using trees. Conditional probability and independence (~4 min). This video uses conditional probability to see if events are independent or not. Conditional probability tree diagram (~11 min). This video uses a tree diagram to work out the following conditional probability question: If someone fails a drug test, what is the…
Probability/Bayes | Health/Medicine | Science/Technology | High School | College | Graduate | Quantitative Literacy -
Lesson/ModuleWeb Portal, Teaching Resource 2016DNA Evidence: Case Study in Probabilities
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case …
This educational module on DNA evidence presents trial testimony, exhibits, and opinions in a case in which federal courts at every level discerned “inaccuracies” in the testimony of a leading expert about probabilities associated with the DNA evidence. By embedding these legal materials in background explanations, critical questions, and short problems, the module supports self-study and class discussions that together can elucidate key principles in scientific reasoning and quantitative analysis and that can help students…
Probability/Bayes | Health/Medicine | Test Performance | Risk Analysis | Injuries/Accidents | Government/Law | Science/Technology | Global | North America | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy -
ArticlePublication 2015Cancer Models and Real-World Data: Better Together
Decision-analytic models synthesize available data on disease burden and intervention effectiveness to project estimates of …
Decision-analytic models synthesize available data on disease burden and intervention effectiveness to project estimates of the long-term consequences of care. While models have been influential in informing US cancer screening guidelines under ideal conditions, incorporating detailed data on real-world screening practice has been limited given the complexity of screening processes and behaviors throughout diverse health delivery systems in the United States. The authors describe the synergies that exist between decision-analytic models and health care utilization…
Calibration/Validation | Health/Medicine | Evidence Synthesis | Mathematical Models | Chronic Disease/Risk | Health Systems | Clinical Care | Science/Technology | North America