Resources Repository
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Lesson/ModuleVideo, Teaching Resource 2018Cost-Effectiveness Analysis Recommendations from the 2nd Panel on CEA in Health & Medicine
This video is intended to summarize the main recommendations about the design and conduct of cost-effectiveness …
This video is intended to summarize the main recommendations about the design and conduct of cost-effectiveness analyses from the Second Panel on Cost-Effectiveness in Health and Medicine (2016), including the use of multiple perspectives, and the use of public protocols to detail how the analysis was conducted. This video is part of the Conducting Cost-Effectiveness Analysis with VA Data (HCEA) free course offered by the U.S. Department of Veterans Affairs Health Services Research and Development group…
Cost-Effectiveness Analysis | Health Systems | Health/Medicine | North America | College | Graduate | Doctoral | Professional | Critical Thinking/Analysis | Policy Translation | Quantitative Literacy -
ArticlePublication 2018Should We Treat Acute Hepatitis C? A Decision and Cost-Effectiveness Analysis
This study examines the potential benefits of treating acute hepatitis C virus (HCV) infection compared …
This study examines the potential benefits of treating acute hepatitis C virus (HCV) infection compared to deferring treatment until the chronic phase, utilizing a microsimulation model. By projecting long-term outcomes such as quality-adjusted life years (QALYs) and costs, the analysis evaluates the cost-effectiveness of initiating therapy during the acute phase. Results indicate that treating acute HCV increases QALYs by 0.02 and costs by $483 per patient not at risk of transmitting HCV, yielding an incremental…
Cost-Effectiveness Analysis | Microsimulation | Decision Analysis | Infectious Diseases | Chronic Disease/Risk | Health/Medicine | North America -
Resource PackWeb Portal, Teaching Resource 2018Resource Pack: Mental Health and Modeling
This resource pack, curated by the Center for Health Decision Science, features resources on modeling …
This resource pack, curated by the Center for Health Decision Science, features resources on modeling approaches applied to mental health. We aim to provide an overview of different techniques to guide researchers and practitioners in applying decision science and economic modeling to this public health challenge. More specifically, this resource pack contains review articles comparing different modeling techniques in the evaluation of treatments for depression, bipolar disorder and schizophrenia. The majority of articles in this…
Cost-Effectiveness Analysis | Costing Methods | Health Outcomes | Evidence Synthesis | Mathematical Models | State-Transition | Microsimulation | Chronic Disease/Risk | Mental Health | Health/Medicine | North America | Europe -
Resource PackPublication, Teaching Resource 2018Resource Pack: Model Calibration and Validation
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to …
This resource pack, curated by the Center for Health Decision Science, provides broad exposure to empirical calibration and validation methods for mathematical models used in health decision analysis. Included are a selection of overviews, guidelines, tutorials, and applications. Given the complexity of diseases and variation in data quality, there are invariably a number of parameters that are unobserved or cannot be estimated directly but can be inferred through the process of model calibration. Model calibration…
Calibration/Validation | Mathematical Models | State-Transition | Dynamic Transmission | Microsimulation | Dynamic Simulation | Health/Medicine -
ArticlePublication 2018Equity Impact Vaccines May Have on Averting Deaths and Medical Impoverishment
In this analysis, authors estimated the number of deaths averted and the number of cases …
In this analysis, authors estimated the number of deaths averted and the number of cases of medical impoverishment averted of ten antigens and their corresponding vaccines across income quintiles for forty-one low- and middle-income countries. The study found that vaccines administered between 2016 and 2030 would prevent 36 million deaths. Vaccines will have the greatest impact on reducing cases of poverty caused by hepatitis B, helping an estimated 14 million people avoid medical impoverishment. An…
Cost-Effectiveness Analysis | Priority Setting/Ethics | Costing Methods | Health Outcomes | Mathematical Models | Infectious Diseases | Child/Nutrition | Global Governance | Economics/Finance | Health/Medicine | Science/Technology | Sub-Saharan Africa | Middle East & North Africa | Asia & Pacific -
ArticlePublication 2018DALYS and QALYs – Does the Choice of Measure Matter?
This article discusses the measurement of health benefits as a key issue in health economic …
This article discusses the measurement of health benefits as a key issue in health economic evaluations. Authors adapted two previously published models, a Markov model for human papilloma virus (HPV) vaccination, and a pneumococcal vaccination deterministic model (PNEUMO) that reported outputs in QALYs to estimate DALYs in 3 settings, Argentina, Chile, and the United Kingdom. While the authors found that QALY gains were larger than DALYs avoided in all countries for HPV, differences using QALYs…
Cost-Effectiveness Analysis | Infectious Diseases | Policy/Regulation | Health/Medicine | Latin America & Caribbean | Europe -
ReviewPublication 2018Patient Variability Seldom Assessed in Cost-Effectiveness Studies
This article in Medical Decision Making reviews 200 articles published in 2014 to determine whether …
This article in Medical Decision Making reviews 200 articles published in 2014 to determine whether each cost-effectiveness analysis (CEA) study reported subgroup results and collected data on the defining characteristics of these subgroups. Since estimates can vary across patient subgroups when characteristics are influenced by preferences, outcome risks, treatment effectiveness, life expectancy, or associated costs it can be important to track and report these differences. The authors identified whether any of the CEA subgroup results…
Cost-Effectiveness Analysis | Preferences/Values | Social Determinants | Health Systems | Policy/Regulation | Health/Medicine | Global -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Introduction to Decision Analysis
In this teaching pack on Introduction to Decision Analysis, students are provided a basic introduction to …
In this teaching pack on Introduction to Decision Analysis, students are provided a basic introduction to the field of decision analysis in the context of public health. After differentiating simple "relatively automatic" decisions from those that might require more systematic analysis, students are introduced to the core elements of a decision analysis (e.g., objectives, alternatives, probabilities, and outcomes), and the basic steps of a decision analysis. Materials include an instructor's note, videos, companion slides, a glossary,…
Cost-Effectiveness Analysis | Decision Psychology | Probability/Bayes | Preferences/Values | Decision Analysis | Health/Medicine | Global | College | Graduate | Critical Thinking/Analysis | Quantitative Literacy -
Teaching PackPublication, Teaching Resource 2022Teaching Pack: Cost-Effectiveness Analysis I
In this teaching pack on Economic Evaluation: Cost-Effectiveness Analysis I, students are introduced to economic evaluation …
In this teaching pack on Economic Evaluation: Cost-Effectiveness Analysis I, students are introduced to economic evaluation as it relates to public health and learn to distinguish between cost-effectiveness and benefit-cost analyses. They learn the concepts of opportunity cost, incremental cost-effectiveness analysis and incremental cost-effectiveness ratios. Finally, students are shown the steps used to conduct a shopping spree cost-effectiveness analysis designed to maximize health under a budget constraint. Materials include an instructor's note, videos, companion slides, a…
Cost-Effectiveness Analysis | Decision Analysis | Health/Medicine | College | Graduate | Doctoral | Critical Thinking/Analysis | Quantitative Literacy