Resources Repository
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ArticlePublication 2013Estimated Mortality Impact of Vaccinations 2011–2020 in 73 GAVI Alliance Countries
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted …
From August to December 2011, a multidisciplinary group with expertise in mathematical modeling was constituted by the GAVI Alliance and the Bill & Melinda Gates Foundation to estimate the impact of vaccination in 73 countries supported by the GAVI Alliance. The number of deaths averted in persons projected to be vaccinated during 2011–2020 was estimated for ten antigens: hepatitis B, yellow fever, Haemophilus influenzae type B (Hib), Streptococcus pneumoniae, rotavirus, Neisseria meningitidis serogroup A, Japanese…
Microsimulation | Mathematical Models | Dynamic Transmission | State-Transition | Science/Technology | Health Outcomes | Infectious Diseases | Global Governance | Economics/Finance | Health/Medicine | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2011Dynamic Policies for Controlling Spread of Emerging Infections
This paper illustrates the design and implementation of a dynamic health policy for the control …
This paper illustrates the design and implementation of a dynamic health policy for the control of a novel strain of influenza, where two types of interventions are assumed to be available during the epidemic: (1) vaccines and antiviral drugs, and (2) transmission reducing measures, such as social distancing or mask use, that may be turned "on" or "off" repeatedly during the course of epidemic. A modeling approach is described for developing dynamic health policies that allow…
Dynamic Simulation | Mathematical Models | Dynamic Transmission | Science/Technology | Infectious Diseases | Health Systems | Policy/Regulation | Health/Medicine | Global -
ArticlePublication 2008Health and Economic Implications of HPV Vaccination in the U.S.
This article reports on a study using models of HPV-16 and HPV-18 transmission and cervical …
This article reports on a study using models of HPV-16 and HPV-18 transmission and cervical carcinogenesis to compare the health and economic outcomes of vaccinating preadolescent girls in the US (at 12 years of age), and vaccinating older girls and women in catch-up programs (to 18, 21, or 26 years of age). The study also examined the health benefits of averting other HPV-16-related and HPV-18-related cancers, the prevention of HPV-6-related and HPV-11-related genital warts and…
Microsimulation | Calibration/Validation | Dynamic Transmission | Science/Technology | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Clinical Care | Economics/Finance | Health/Medicine | North America -
ArticlePublication 2008Mathematical Models of Cervical Cancer Prevention in the Asia Pacific Region
This article reports on a model-based approach to estimate averted cervical cancer cases and deaths, …
This article reports on a model-based approach to estimate averted cervical cancer cases and deaths, disability-adjusted life years (DALYs) and incremental cost-effectiveness ratios (I$/DALY averted) for vaccination of young adolescent girls against human papillomavirus (HPV) types 16 and 18. The authors used population-based and epidemiologic data for 25 countries in Asia (22 GAVI-Alliance eligible countries, Thailand, China and Japan). They found that an absolute reduction in lifetime cancer risk varied across countries, depending on incidence,…
Microsimulation | Mathematical Models | Calibration/Validation | Science/Technology | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Economics/Finance | Health/Medicine | Asia & Pacific -
ArticlePublication 2008Mathematical Models of Cervical Cancer Prevention in Latin America and the Caribbean
This article reports on a model-based approach estimated averted cervical cancer cases and deaths, disability-adjusted …
This article reports on a model-based approach estimated averted cervical cancer cases and deaths, disability-adjusted life years (DALYs) and incremental cost-effectiveness ratios (I$/DALY averted) for human papillomavirus (HPV) vaccination of young adolescent girls using population and epidemiologic data for 33 countries in Latin America and the Caribbean (LAC). The authors found that an absolute reduction in lifetime cancer risk varied between countries, depending on incidence, proportion attributable to HPV-16 and 18, and population age-structure; for…
Microsimulation | Calibration/Validation | State-Transition | Science/Technology | Costing Methods | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Economics/Finance | Health/Medicine | Latin America & Caribbean -
ArticlePublication 2021Identifying Credible Sources of Health Information in Social Media: Principles and Attributes
Social media is widely used as a source of health information for the general public. …
Social media is widely used as a source of health information for the general public. The potential for information shared through social media to influence health outcomes necessitates action by social media platforms to enhance access and exposure to high-quality, science-based information. This paper summarizes the work of an independent advisory group convened by the National Academy of Medicine that deliberated and gathered information to develop a set of initial principles and attributes that could…
Decision Psychology | Education/Labor | Science/Technology | Preferences/Values | Social Determinants | Policy/Regulation | Culture/Society | Health/Medicine | North America -
ArticlePublication 2021Misinformation and Public Opinion of Science and Health
This article summarizes the literature on misinformation, beginning with an overview of the most common …
This article summarizes the literature on misinformation, beginning with an overview of the most common definitions of misinformation (and related terms) in the communication literature and then a review of academic studies in the areas of science and health. The author acknowledges four overarching questions that have emerged prominently in recent years: (1) What does “misinformation” (and the terms that are oftentimes treated synonymously) mean? (2) How big of a problem is it in areas…
Decision Psychology | Education/Labor | Science/Technology | Preferences/Values | Social Determinants | Climate/Environment | Culture/Society | Energy/Engineering | Global | North America -
ArticlePublication 2021COVID-19, Fake News, and Vaccines: Should Regulation Be Implemented?
This article analyzes issues concerning the establishment of compulsory vaccination against COVID-19, as well as …
This article analyzes issues concerning the establishment of compulsory vaccination against COVID-19, as well as the role of misinformation as a disincentive – especially when published by health professionals – and citizen acceptance of measures in this regard. Data from different surveys revealed a high degree of hesitation rather than outright opposition to vaccines. The most frequent complaint related to the COVID-19 vaccination was the fear of side effects. Within the Spanish and European legislative…
Decision Psychology | Education/Labor | Science/Technology | Preferences/Values | Infectious Diseases | Social Determinants | Policy/Regulation | Culture/Society | Government/Law | Health/Medicine | Global -
ArticlePublication 2020New Fronts in the War on Misinformation
The countless false claims that have spread alongside the novel coronavirus – inaccurate advice about …
The countless false claims that have spread alongside the novel coronavirus – inaccurate advice about how to prevent the virus, for example, and conspiracy theories about its origins – are just the latest manifestation of an ongoing problem: the online proliferation of misinformation about science and health. The National Academies hosted and helped organize three events focused on countering misinformation: The MisinfoCon conference, a Wikipedia Edit-a-thon, and a meeting to explore ways to expand successful…
Decision Psychology | Education/Labor | Science/Technology | Preferences/Values | Infectious Diseases | Social Determinants | Policy/Regulation | Culture/Society | Government/Law | Health/Medicine | North America