Resources Repository
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ArticlePublication 2011Health and Economic Impact of HPV 16/18 Vaccination and Cervical Cancer Screening in Eastern Africa
In this article the authors use epidemiologic data from Kenya, Mozambique, Tanzania, Uganda, and Zimbabwe …
In this article the authors use epidemiologic data from Kenya, Mozambique, Tanzania, Uganda, and Zimbabwe to develop models of HPV-related infection and disease. For each country, they assessed HPV vaccination of girls before age 12 followed by screening with HPV DNA testing once, twice, or three times per lifetime (at ages 35, 40, 45). For women over age 30, they assessed only screening (with HPV DNA testing up to three times per lifetime or VIA…
Cost-Effectiveness Analysis | Calibration/Validation | Health/Medicine | Sub-Saharan Africa | Microsimulation | Infectious Diseases | Chronic Disease/Risk | Clinical Care | Economics/Finance | Science/Technology -
ArticlePublication 2010Health and Economic Impact of Rotavirus Vaccination in GAVI-Eligible Countries
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately …
Rotavirus infection is responsible for about 500,000 deaths annually, and the disease burden is disproportionately borne by children in low-income countries. Motivated by the global recommendation by the WHO that all countries include infant rotavirus vaccination in their national immunization programs, the objective of this analysis was to provide information on the expected health, economic and financial consequences of rotavirus vaccines in the 72 GAVI support-eligible countries. The authors synthesized population-level data from various sources (primarily from…
Cost-Effectiveness Analysis | Health Outcomes | Health/Medicine | Sub-Saharan Africa | Mathematical Models | State-Transition | Infectious Diseases | Child/Nutrition | Economics/Finance | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2023Out-of-Pocket Expenditures & Financial Risks Associated with Treatment of Vaccine-Preventable Diseases in Ethiopia
This study investigates out-of-pocket (OOP) expenditures and associated catastrophic health expenditures (CHEs) for vaccine-preventable diseases …
This study investigates out-of-pocket (OOP) expenditures and associated catastrophic health expenditures (CHEs) for vaccine-preventable diseases (VPDs) in Ethiopia. Through a cross-sectional costing analysis, data on OOP direct medical and nonmedical expenditures were collected from 995 households in 54 health facilities nationwide. The study focuses on VPDs in children under 5 years for pneumonia, diarrhea, measles, and pertussis, and in children under 15 years for meningitis. Mean OOP expenditures per disease episode ranged from $5·6 to…
Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa | Costing Methods | Mathematical Models | Child/Nutrition | Chronic Disease/Risk -
ArticlePublication 2022Modeling the Relative Risk of Incidence and Mortality of Select Vaccine-Preventable Diseases
Immunization is one of the most effective public health interventions, saving millions of lives every …
Immunization is one of the most effective public health interventions, saving millions of lives every year. Ethiopia has seen gradual improvements in immunization coverage and access to child health care services; however, inequalities in child mortality across wealth quintiles and regions remain persistent. This paper models the relative distributional incidence and mortality of four vaccine-preventable diseases (VPDs) (rotavirus diarrhea, human papillomavirus, measles, and pneumonia) by wealth quintile and geographic region in Ethiopia. The authors approach…
Evidence Synthesis | Health/Medicine | Sub-Saharan Africa | Priority Setting/Ethics | Infectious Diseases | Social Determinants -
ArticlePublication 2022Re-Evaluating the Health Impact and Cost-Effectiveness of Tuberculosis Prevention for Modern ART Cohorts
TB preventive therapy (TPT) is widely accepted to be cost-effective for reducing TB incidence in …
TB preventive therapy (TPT) is widely accepted to be cost-effective for reducing TB incidence in HIV-infected individuals receiving antiretroviral therapy (ART). However, as individuals initiate ART earlier in the course of disease, TB incidence is lower, and it is unclear how ART cost-effectiveness has changed. This study assessed the cost-effectiveness of TPT in contemporary ART cohorts. The authors developed a microsimulation model of TB and HIV and parameterised it using data from a large HIV…
Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa | Microsimulation | Infectious Diseases | Global -
ArticlePublication 2022Healthcare Cost of Overweight & Obesity in South Africa
This analysis estimates the healthcare cost associated with treatment of weight-related conditions from the perspective …
This analysis estimates the healthcare cost associated with treatment of weight-related conditions from the perspective of the South African public sector payer. The authors report that the total cost of overweight and obesity is estimated to be ZAR33,194 million in 2020, representing approximately 15% of government health expenditure and equivalent to 0.67% of GDP. This analysis is an example of a bottom-up gross costing approach. The study draws South African data from multiple sources to estimate…
Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa | Costing Methods | Chronic Disease/Risk | Health Systems -
ArticlePublication 2022Trauma Care in Public and Private Hospitals in Addis Ababa, Ethiopia: Cross-Sectional Observational Study
This study examines the financial risks associated with seeking trauma care for road traffic injuries …
This study examines the financial risks associated with seeking trauma care for road traffic injuries in Addis Ababa, Ethiopia. Conducting a cross-sectional survey from December 2018 to February 2019 in three public and one private hospital, the research analyzes out-of-pocket (OOP) expenditures related to trauma care. Data from 452 trauma cases are collected, encompassing both medical and non-medical costs. Catastrophic health expenditures, defined as OOP health expenditures exceeding 10% of total household expenditures, are assessed,…
Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa | Injuries/Accidents -
ArticlePublication 2020Burden of Household OOP Health Expenditures
This article, published in Health Policy and Planning, estimates the incidence of catastrophic and impoverishing …
This article, published in Health Policy and Planning, estimates the incidence of catastrophic and impoverishing health expenditures using data from the 2015/16 Ethiopian household consumption and expenditure and welfare monitoring surveys. The authors compute the incidence of catastrophic health expenditures (CHE) at 10% and 25% thresholds of total household consumption and 40% threshold of household capacity to pay. Impoverishing health expenditures (IHE) are calculated using Ethiopia's national poverty line (ETB 7184 per adult per year).…
Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa | Health Systems -
ArticlePublication 2020Economic Evaluation of HBV Birth Dose Vaccination
This article, published in Cost Effectiveness and Resource Allocation, examines the cost-effectiveness of a birth …
This article, published in Cost Effectiveness and Resource Allocation, examines the cost-effectiveness of a birth dose of HBV vaccine in a medical setting in Ethiopia. The authors construct a decision analytic model with a Markov process to estimate the costs and effects of a birth dose of HBV vaccine, compared with current practices in Ethiopia. Based on the cost-effectiveness findings, introducing a birth dose of HBV vaccine in Ethiopia would likely be highly cost-effective. Such…
Cost-Effectiveness Analysis | Health/Medicine | Sub-Saharan Africa | Infectious Diseases | Health Systems