Resources Repository
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GuidelinesPublication 2012Modeling Good Research Practices - Overview: A Report of the ISPOR-SMDM Modeling Task Force-1
This paper provides an overview of the work of the joint Task Force between the …
This paper provides an overview of the work of the joint Task Force between the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) and the Society for Medical Decision Making (SMDM), provides the overarching recommendations, and discusses future work that is needed. The audience for these papers includes anyone who build models, stakeholders who utilize their results, and those concerned with the use of models to support decision making. This article is part 1 of…
Calibration/Validation | Value of Information | Costing Methods | Health Outcomes | Mathematical Models | State-Transition | Dynamic Transmission | Microsimulation | Dynamic Simulation | Decision Analysis | Infectious Diseases | Health/Medicine -
GuidelinesPublication 2012Model Parameter Estimation and Uncertainty Analysis: A Report of the ISPOR-SMDM Modeling Task Force-6
This paper discusses methods for the reporting of uncertainty, both in terms of deterministic sensitivity …
This paper discusses methods for the reporting of uncertainty, both in terms of deterministic sensitivity analysis techniques and probabilistic methods. Stochastic (first-order) uncertainty is distinguished from both parameter (second-order) uncertainty and from heterogeneity, with structural uncertainty relating to the model itself forming another level of uncertainty. The article describes the process of estimating model inputs, whether these are point estimates or distributions. It also explores the link between parameter uncertainty, decision uncertainty, and value-of-information analysis.…
Calibration/Validation | Value of Information | Mathematical Models | Health/Medicine -
ToolWeb Portal 2023CDC Resource Portal: Diagnostic Tests for SARS-CoV-2
The Centers for Disease Control and Prevention (CDC) provides a broad range of resources about …
The Centers for Disease Control and Prevention (CDC) provides a broad range of resources about diagnostic tests for SARS-CoV-2 aimed at the general public, health professionals and laboratory personnel. The overviews and guidelines for health professionals provide comprehensive information about the current available diagnostics, their strengths and limitations, their performance characteristics and guidelines for their use and interpretation. Selected topics included are provided below. Overview of Testing for SARS-CoV-2, the Virus That Causes COVID-19. Interim…
Test Performance | Infectious Diseases | Clinical Care | Health/Medicine | Science/Technology | North America -
ToolInteractive 2020COVID-19 Antibody Tests: Calculator for Interpreting Test Results
Antibody testing can determine previous exposure to SARS-CoV-2 virus. This interactive calculator, linked to the article …
Antibody testing can determine previous exposure to SARS-CoV-2 virus. This interactive calculator, linked to the article below* on antibody testing for SARS-CoV-2 virus, allows users to vary the prior probability of infection, the sensitivity of SARS-CoV-2 antibody testing, and the specificity of SARS-CoV-2 antibody testing. Key points made in the article accompanying the interactive include: (1) antibody testing is likely to be most useful 2 weeks after infection, (2) sensitivity and specificity will vary over time and…
Test Performance | Probability/Bayes | Technology Assessment | Infectious Diseases | Clinical Care | Health/Medicine | Science/Technology -
GuidelinesPublication 2017Guidelines for Regulatory Impact Analysis: A Primer
This “Frequently Asked Question” style document gives a brief overview of Regulatory Impact Analysis (RIA), …
This “Frequently Asked Question” style document gives a brief overview of Regulatory Impact Analysis (RIA), a method used by the US government to assess the consequences of proposed policies and their alternatives. The document is aimed at those who are new to the topic. RIAs apply a framework for collecting, organizing, and evaluating data. They help ensure that regulatory actions are justified and necessary to achieve social goals, and that these actions are implemented in the…
Benefit-Cost Analysis | Business/Industry | Government/Law | North America -
GuidelinesWeb Portal 2013Handbook for Diagnostic Test Accuracy
The Cochrane handbook for reviews of diagnostic test accuracy is produced by the Cochrane Diagnostic …
The Cochrane handbook for reviews of diagnostic test accuracy is produced by the Cochrane Diagnostic Test Accuracy Working Group. This group was constituted by the Steering Group of the Cochrane Collaboration to implement the publication of systematic reviews of diagnostic test accuracy within the Cochrane Collaboration. The handbook is structured as Part 1. Cochrane Reviews which contains four chapters and Part 2. General Methods for Cochrane Reviews of Diagnostic Test Accuracy which contains seven chapters. This web…
Test Performance | Evidence Synthesis | Health Systems | Health/Medicine | Global -
GuidelinesPublication 2014EPA Guidelines for Preparing Economic Analyses
The US Environmental Protection Agency (EPA) Guidelines for Preparing Economic Analyses provide a framework for …
The US Environmental Protection Agency (EPA) Guidelines for Preparing Economic Analyses provide a framework for assessing the impacts of environmental regulations and policies that has been extensively peer-reviewed and is widely-applied both within and outside of the agency. The Guidelines discuss: (1) statutory and executive order requirements for conducting economic analyses; (2) identifying the need for policy action; (3) regulatory and non-regulatory approaches to pollution control; (4) baseline definition; (5) discounting future benefits and costs;…
Benefit-Cost Analysis | Preferences/Values | Priority Setting/Ethics | Decision Analysis | Environmental Health | Policy/Regulation | Climate/Environment | Government/Law | North America | Critical Thinking/Analysis -
GuidelinesPublication 2014Methods for Economic Evaluation Project
This report details the work of the Methods for Economic Evaluation Project (MEEP), which aims …
This report details the work of the Methods for Economic Evaluation Project (MEEP), which aims to promote a consistency in the methods used for economic evaluations. The report is targeted especially at low and middle-income countries (LMICs). The Bill and Melinda Gates Foundation is a major funder of health economic evaluations in LMICs, but there is substantial variation in the methods used and the quality of the analyses produced. The report drew on expertise from…
Benefit-Cost Analysis | Priority Setting/Ethics | Costing Methods | Cost-Effectiveness Analysis | Climate/Environment | Education/Labor | Health/Medicine | Global -
GuidelinesPublication 2012Model Transparency and Validation: A Report of the ISPOR-SMDM Modeling Task Force-7
This paper discusses how to improve trust in the use of health care models through …
This paper discusses how to improve trust in the use of health care models through validation and transparency. Validation involves face validity (wherein experts evaluate model structure, data sources, assumptions, and results), verification or internal validity (check accuracy of coding), cross validity (comparison of results with other models analyzing same problem), external validity (comparing model results to real-world results), and predictive validity (comparing model results with prospectively observed events). Recommendations are provided for nontechnical description…
Calibration/Validation | Costing Methods | Health Outcomes | Mathematical Models | Health/Medicine