Resources Repository
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GuidelinesPublication 2014Principles of Good Practice for Budget Impact Analysis
This report provides recommendations for conducting a Budget Impact Analysis from the ISPOR 2012 Budget …
This report provides recommendations for conducting a Budget Impact Analysis from the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force. National regulatory agencies such as the National Institute for Health and Clinical Excellence in England and Wales and the Pharmaceutical Benefits Advisory Committee in Australia, as well as managed care organizations in the United States, now require that companies submit estimates of both the cost-effectiveness and the likely impact of the new health-care…
Costing Methods | Health/Medicine | Government/Law | Europe -
GuidelinesPublication 2014Methods for Economic Evaluation Project
This report details the work of the Methods for Economic Evaluation Project (MEEP), which aims …
This report details the work of the Methods for Economic Evaluation Project (MEEP), which aims to promote a consistency in the methods used for economic evaluations. The report is targeted especially at low and middle-income countries (LMICs). The Bill and Melinda Gates Foundation is a major funder of health economic evaluations in LMICs, but there is substantial variation in the methods used and the quality of the analyses produced. The report drew on expertise from…
Costing Methods | Health/Medicine | Priority Setting/Ethics | Benefit-Cost Analysis | Cost-Effectiveness Analysis | Climate/Environment | Education/Labor | Global -
GuidelinesPublication 2013Consolidated Health Economic Evaluation Reporting Standards
These guidelines demonstrate how to present the findings of Health Economic Evaluations. They are aimed …
These guidelines demonstrate how to present the findings of Health Economic Evaluations. They are aimed at researchers and reviewers in no particular region. Previously published checklists or guidance documents related to reporting economic evaluations were identified from a systematic review and subsequent survey of task force members. A two-round, modified Delphi Panel with representatives from academia, clinical practice, industry, and government, as well as the editorial community, was used to identify a minimum set of…
Costing Methods | Health/Medicine | Cost-Effectiveness Analysis | Health Systems | Policy/Regulation | Global -
GuidelinesPublication 2013Decision and Simulation Modeling in Systematic Reviews
The purpose of this review is to provide guidance for determining when incorporating a decision-analytic …
The purpose of this review is to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The purpose of systematic reviews is to synthesize the current scientific literature on a particular topic in the form of evidence reports and technology assessments to assist public and private organizations in developing strategies that improve the quality of health care and decision making. However, there…
Decision Analysis | Health/Medicine | Evidence Synthesis | Mathematical Models | Infectious Diseases | Child/Nutrition | Chronic Disease/Risk | North America -
GuidelinesPublication 2012Model Transparency and Validation: A Report of the ISPOR-SMDM Modeling Task Force-7
This paper discusses how to improve trust in the use of health care models through …
This paper discusses how to improve trust in the use of health care models through validation and transparency. Validation involves face validity (wherein experts evaluate model structure, data sources, assumptions, and results), verification or internal validity (check accuracy of coding), cross validity (comparison of results with other models analyzing same problem), external validity (comparing model results to real-world results), and predictive validity (comparing model results with prospectively observed events). Recommendations are provided for nontechnical description…
Costing Methods | Health/Medicine | Health Outcomes | Mathematical Models | Calibration/Validation -
GuidelinesPublication 2012Conceptualizing a Model: A Report of the ISPOR-SMDM Modeling Task Force-2
This article provides a series of consensus-based best practices regarding the process of model conceptualization, …
This article provides a series of consensus-based best practices regarding the process of model conceptualization, specifically when models are used to inform medical decisions and health-related resource allocation. The authors divide the conceptualization process into two distinct components: the conceptualization of the problem, which converts knowledge of the health care process or decision into a representation of the problem, followed by the conceptualization of the model itself, which matches the attributes and characteristics of a…
Decision Analysis | Health/Medicine | Mathematical Models -
ArticlePublication 2008Economic Burden of Personality Disorders in Mental Health Care
This paper aimed to investigate the economic burden of patients with personality disorders in mental …
This paper aimed to investigate the economic burden of patients with personality disorders in mental health care. The direct and indirect costs were assessed for 1740 study participants with a clinical diagnosis of personality disorders using the Trimbos and Institute for Medical Technology Assessment Questionnaire on Costs Associated with Psychiatric Illness. Results indicated that the mean total costs in the 12 months prior to treatment were €11,126 per patient. Two thirds (66.5%) of these costs consisted…
Costing Methods | Health/Medicine | Evidence Synthesis | Mental Health | Europe -
ArticlePublication 2007Making the Right Decision: Benjamin Franklin in 1736
This paper applies a decision analytic approach to a past decision made by Benjamin Franklin with regard to …
This paper applies a decision analytic approach to a past decision made by Benjamin Franklin with regard to inoculating his son against smallpox. Benjamin Franklin in his autobiography said: “In 1736 I lost one of my sons, a fine boy of four years old, by the smallpox taken in the common way. I long regretted bitterly and still regret that I had not given it to him by inoculation. This I mention for the sake of the parents who…
Decision Analysis | Health/Medicine | Infectious Diseases -
ArticlePublication 2006Can Discrete Event Simulation be of Use in Modeling Major Depression?
This article, published in Cost Effectiveness and Resource Allocation, reviews the published literature on Markov …
This article, published in Cost Effectiveness and Resource Allocation, reviews the published literature on Markov models in depression and identified potential limitations in using this particular modelling approach in this disease area. Additionally, the authors develop a “Discrete Event Simulation” (DES) model to investigate the benefits and drawbacks of this simulation method compared with Markov modelling techniques. The findings of this study indicate that the most important limitation of using Markov models in depression is…
Decision Analysis | Health/Medicine | State-Transition | Microsimulation | Mental Health