Resources Repository
-
GuidelinesPublication 2013Guide to the Methods of Technology Appraisal 2013
The National Institute for Health and Care Excellence (NICE, or the Institute) provides guidance to …
The National Institute for Health and Care Excellence (NICE, or the Institute) provides guidance to the NHS in England on the clinical and cost effectiveness of selected new and established technologies. The Institute undertakes appraisals of health technologies at the request of the Department of Health. Guidance produced by the Institute on health technologies is also applied selectively in Northern Ireland, Scotland and Wales. The purpose of this document is to provide an overview of…
Priority Setting/Ethics | Cost-Effectiveness Analysis | Technology Assessment | Health Systems | Policy/Regulation | Government/Law | Health/Medicine | Europe -
GuidelinesPublication 2013Consolidated Health Economic Evaluation Reporting Standards
These guidelines demonstrate how to present the findings of Health Economic Evaluations. They are aimed …
These guidelines demonstrate how to present the findings of Health Economic Evaluations. They are aimed at researchers and reviewers in no particular region. Previously published checklists or guidance documents related to reporting economic evaluations were identified from a systematic review and subsequent survey of task force members. A two-round, modified Delphi Panel with representatives from academia, clinical practice, industry, and government, as well as the editorial community, was used to identify a minimum set of…
Costing Methods | Cost-Effectiveness Analysis | Health Systems | Policy/Regulation | Health/Medicine | Global -
GuidelinesPublication 2013Decision and Simulation Modeling in Systematic Reviews
The purpose of this review is to provide guidance for determining when incorporating a decision-analytic …
The purpose of this review is to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The purpose of systematic reviews is to synthesize the current scientific literature on a particular topic in the form of evidence reports and technology assessments to assist public and private organizations in developing strategies that improve the quality of health care and decision making. However, there…
Decision Analysis | Evidence Synthesis | Mathematical Models | Infectious Diseases | Child/Nutrition | Chronic Disease/Risk | Health/Medicine | North America -
GuidelinesPublication 2013Economic Analyses to Support Decisions about HPV Vaccination in Low- and Middle-Income Countries: Consensus Report and Guide
Low- and middle-income countries need to consider economic issues such as cost-effectiveness, affordability and sustainability …
Low- and middle-income countries need to consider economic issues such as cost-effectiveness, affordability and sustainability before introducing a program for human papillomavirus (HPV) vaccination. However, many such countries lack the technical capacity and data to conduct their own analyses. This report describes the consensus of an expert group convened by the World Health Organization, prioritizing key issues to be addressed when considering economic analyses to support HPV vaccine introduction in these countries. The expert group…
Costing Methods | Health Outcomes | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Economics/Finance | Health/Medicine | Science/Technology | Sub-Saharan Africa | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
GuidelinesPublication 2012Conceptualizing a Model: A Report of the ISPOR-SMDM Modeling Task Force-2
This article provides a series of consensus-based best practices regarding the process of model conceptualization, …
This article provides a series of consensus-based best practices regarding the process of model conceptualization, specifically when models are used to inform medical decisions and health-related resource allocation. The authors divide the conceptualization process into two distinct components: the conceptualization of the problem, which converts knowledge of the health care process or decision into a representation of the problem, followed by the conceptualization of the model itself, which matches the attributes and characteristics of a…
Decision Analysis | Mathematical Models | Health/Medicine -
GuidelinesPublication 2012Model Parameter Estimation and Uncertainty Analysis: A Report of the ISPOR-SMDM Modeling Task Force-6
This paper discusses methods for the reporting of uncertainty, both in terms of deterministic sensitivity …
This paper discusses methods for the reporting of uncertainty, both in terms of deterministic sensitivity analysis techniques and probabilistic methods. Stochastic (first-order) uncertainty is distinguished from both parameter (second-order) uncertainty and from heterogeneity, with structural uncertainty relating to the model itself forming another level of uncertainty. The article describes the process of estimating model inputs, whether these are point estimates or distributions. It also explores the link between parameter uncertainty, decision uncertainty, and value-of-information analysis.…
Calibration/Validation | Value of Information | Mathematical Models | Health/Medicine -
GuidelinesPublication 2011HPV Vaccine Introduction in LMIC's: Guidance on the Use of Cost-Effectiveness Models
This article is a literature review of HPV vaccination models suitable for low-income and middle-income …
This article is a literature review of HPV vaccination models suitable for low-income and middle-income country use to provide information about the feasibility of using such models in a developing country setting. The authors evaluated models in terms of their capacity, requirements, limitations and comparability. Their literature review identified six HPV vaccination models suitable for low-income and middle-income country use and representative of the literature in terms of provenance and model structure. Each model was…
Calibration/Validation | Mathematical Models | Cost-Effectiveness Analysis | Infectious Diseases | Chronic Disease/Risk | Health Systems | Clinical Care | Health/Medicine | Science/Technology | Global -
GuidelinesPublication 2011Calibrating Models in Economic Evaluation
This article provides guidance on the theoretical underpinnings of different calibration methods used for mathematical …
This article provides guidance on the theoretical underpinnings of different calibration methods used for mathematical models for economic evaluations. The calibration process is divided into seven steps and different potential methods at each step are discussed, focusing on the particular features of disease models in economic evaluation. The seven steps are (i) Which parameters should be varied in the calibration process? (ii) Which calibration targets should be used? (iii) What measure of goodness of fit…
Calibration/Validation | Mathematical Models | Health/Medicine -
GuidelinesPublication 2007Preference Measurement in Economic Analysis
This guide includes an overview of the concepts of preference measurement and quality-adjusted life years, …
This guide includes an overview of the concepts of preference measurement and quality-adjusted life years, a description of the most common techniques used for measuring preferences in economic evaluation, a summary of experience measuring preferences in the VA Cooperative Studies Program.
Preferences/Values | Health Outcomes | Health/Medicine | North America