Resources Repository
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ArticlePublication 2017OOP Expenditures for Cardiovascular Disease
This article, published in BMJ Global Health, aims to estimate the magnitude and intensity of …
This article, published in BMJ Global Health, aims to estimate the magnitude and intensity of catastrophic health expenditure (CHE) and factors associated with CHE for the prevention and treatment of cardiovascular disease in hospitals in Addis Ababa. Seeking prevention and treatment services for cardiovascular disease in Addis Ababa was found to pose substantial financial burden on households, affecting the poorest and those who reside outside Addis Ababa more. Economic and geographic inequalities should therefore be…
Health/Medicine | Sub-Saharan Africa | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health Systems -
ArticlePublication 2017Using Data-Driven Agent-Based Models to Forecast Emerging Infectious Diseases
This paper describes an agent-based model framework developed to forecast the 2014-15 Ebola epidemic, which …
This paper describes an agent-based model framework developed to forecast the 2014-15 Ebola epidemic, which was subsequently used in the Ebola forecasting challenge. Producing timely and reliable forecasts for an epidemic of an emerging infectious disease is a challenge. Epidemiologists and policy makers have to deal with poor data quality, limited understanding of the disease dynamics, a rapidly changing social environment and the uncertainty around the effects of various interventions in place. In this setting,…
Health/Medicine | Sub-Saharan Africa | Microsimulation | Calibration/Validation | Dynamic Simulation | Infectious Diseases -
ArticlePublication 2017Household Expenditures on Pneumonia and Diarrhoea Treatment
This article, published in BMJ Global Health, quantifies household out-of-pocket (OOP) expenditure for treatment of …
This article, published in BMJ Global Health, quantifies household out-of-pocket (OOP) expenditure for treatment of childhood pneumonia and diarrhoea and estimates its impact on poverty for different socioeconomic groups in Ethiopia. The study finds that wealthier and urban households have higher OOP payments, but poorer and rural households are more likely to be impoverished due to medical payments. The present circumstances call for revisiting the existing health financing strategy for high-priority services that place a…
Health/Medicine | Sub-Saharan Africa | Costing Methods | Infectious Diseases | Child/Nutrition | Health Systems -
ArticlePublication 2016Assessing Medical Impoverishment by Cause
This article, published in BMC Medicine, utilizes a cost and epidemiological model to propose an …
This article, published in BMC Medicine, utilizes a cost and epidemiological model to propose an assessment of the burden of medical impoverishment in Ethiopia (i.e., the number of households crossing a poverty line due to out-of-pocket (OOP) direct medical expenses). Among 20 leading causes of mortality, the authors estimate the burden of medical impoverishment to be around 350,000 poverty cases, with the top three causes of medical impoverishment attributed to diarrhea, lower respiratory infections, and…
Health/Medicine | Sub-Saharan Africa | Costing Methods | Health Systems -
ArticlePublication 2016Cost-Effectiveness of Diagnosing HIV Infection During Early Infancy in South Africa
In this study the clinical impact and cost-effectiveness of four different early infant HIV diagnosis …
In this study the clinical impact and cost-effectiveness of four different early infant HIV diagnosis (EID) testing strategies for HIV-exposed infants in South Africa were compared using a microsimulation model. The strategies included (1) no EID (diagnosis only after illness), (2) and (3) testing once (at birth alone or at 6 weeks of age alone), and (4) testing twice (at birth and 6 weeks of age). Findings showed that the testing at birth alone strategy…
Health/Medicine | Sub-Saharan Africa | Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Child/Nutrition -
ArticlePublication 2016Prevention and Treatment of Cardiovascular Disease
This article, published in Cost Effectiveness and Resource Allocation, aims to assess the cost-effectiveness of …
This article, published in Cost Effectiveness and Resource Allocation, aims to assess the cost-effectiveness of prevention and treatment of ischemic heart disease (IHD) and stroke in an Ethiopian setting. Fifteen single interventions and sixteen intervention packages are assessed from a healthcare provider perspective. The results indicate that the escalating burden of CVD and its risk factors warrants timely action. Selected CVD intervention packages could be scaled up at a modest budget increase, but the level…
Health/Medicine | Sub-Saharan Africa | Cost-Effectiveness Analysis | Chronic Disease/Risk | Health Systems -
ArticlePublication 2016Quality Improvement for Cardiovascular Disease Care in Low- and Middle-Income Countries: A Systematic Review
The majority of global cardiovascular disease (CVD) burden falls on people living in low- and …
The majority of global cardiovascular disease (CVD) burden falls on people living in low- and middle-income countries (LMICs). As part of the Disease Control Priorities Three (DCP3) Study efforts addressing quality improvement, the authors reviewed and summarized currently available evidence on interventions to improve quality of clinic-based CVD prevention and management in LMICs. Using a narrative review of published comparative clinical trials that evaluated efficacy or effectiveness of clinic-based CVD prevention and management quality improvement…
Health/Medicine | Sub-Saharan Africa | Health Outcomes | Evidence Synthesis | Chronic Disease/Risk | Health Systems | Middle East & North Africa | Latin America & Caribbean | Asia & Pacific -
ArticlePublication 2016Inequalities in Maternal and Child Health Utilization
This article, published in BMC Health Services Research, aims to measure changes in inequality in …
This article, published in BMC Health Services Research, aims to measure changes in inequality in access to maternal and child health (MCH) interventions and the effect of primary health care (PHC) facilities expansion on the inequality in access to care in Ethiopia. The authors utilize The Demographic and Health Survey datasets from Ethiopia (2005 and 2011) to calculate changes in utilization of MCH interventions and child morbidity and estimate concentration and horizontal inequity indices. The…
Health/Medicine | Sub-Saharan Africa | Maternal/Reproductive Health | Child/Nutrition | Health Systems -
ArticlePublication 2015Cost-Effectiveness of First-Line Antiretroviral Therapy for HIV-Infected African Children Less Than 3 Years of Age
This article compares the cost-effectiveness of different strategies of first-line antiretroviral therapy (no ART, first-line nevirapine …
This article compares the cost-effectiveness of different strategies of first-line antiretroviral therapy (no ART, first-line nevirapine with second-line lopinavir/ritonavir, and first-line lopinavir/ritonavir with second-line nevirapine) for HIV-infected children less than 3 years of age in Africa, using the Cost-Effectiveness of Preventing AIDS Complications- Pediatric model and data obtained from the International Maternal, Pediatric, and Adolescent Clinical Trial P1060 trial. Results demonstrated that both ART regimens were very cost-effective compared to no ART. First-line lopinavir/ritonavir led to longer…
Health/Medicine | Sub-Saharan Africa | Microsimulation | Cost-Effectiveness Analysis | Infectious Diseases | Child/Nutrition