Resources Repository
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ReviewPublication 2001Modeling for Health Care and Other Policy Decisions: Uses, Roles and Validity
This is a review article of the role of modeling approaches to guide decision making …
This is a review article of the role of modeling approaches to guide decision making in health care and other domains. The role of models to support recommendations on the cost-effective use of medical technologies and pharmaceuticals is controversial. At the heart of the controversy is the degree to which experimental or other empirical evidence should be required prior to model use. The authors argue that the controversy stems in part from a misconception that…
Evidence Synthesis | Priority Setting/Ethics | Health/Medicine | Mathematical Models | Technology Assessment | Environmental Health | Health Systems | Policy/Regulation | Business/Industry | Climate/Environment | Economics/Finance | Energy/Engineering | Government/Law | North America -
ReviewPublication 2022Systematic Review of Economic Evaluations of COVID-19 Interventions: Non-Health Impacts and Distributional Issues
The authors conducted a systematic review of economic evaluations of COVID-19 interventions and assessed whether …
The authors conducted a systematic review of economic evaluations of COVID-19 interventions and assessed whether they incorporated non-health impacts and distributional concerns. Among the 70 articles included, more than half (56%) included at least one non-health impact, although only 21% incorporated non-economic consequences. Only 17% examined subgroups of interest. The median ICER for the entire sample was $67,000/quality-adjusted life-year (QALY) (interquartile range [IQR] $9000-$893,000/QALY). Interventions including a pharmaceutical component yielded a median ICER of $93,000/QALY (IQR…
Evidence Synthesis | Health/Medicine | Cost-Effectiveness Analysis | Infectious Diseases | Social Determinants | Culture/Society | Economics/Finance | North America -
ReviewPublication 2020Public Health and Online Misinformation: Challenges and Recommendations
The internet has become a popular resource to learn about health and to investigate one's …
The internet has become a popular resource to learn about health and to investigate one's own health condition. However, given the large amount of inaccurate information online, people can easily become misinformed. Individuals have always obtained information from outside the formal health care system, so how has the internet changed people's engagement with health information? This review explores how individuals interact with health misinformation online, whether it be through search, user-generated content, or mobile apps.…
Evidence Synthesis | Health/Medicine | Social Determinants | Health Systems | Culture/Society | North America -
ReviewPublication 2018Equity Considerations in CEA: Rotavirus Vaccine in LMIC's
The authors used a systematic review of the literature to identify economic evaluations of rotavirus …
The authors used a systematic review of the literature to identify economic evaluations of rotavirus vaccine in LMICs and assess the extent to which equity was considered in the objectives, analysis, and results. They used equity-related indicators provided in the Guidance on Priority Setting in Health Care (GPS-Health) checklist criteria resulting in 18 unique indicators tracked. The authors found that some articles incorporated the indicators in their model inputs (20%) while the majority (80%) presented…
Evidence Synthesis | Health/Medicine | Cost-Effectiveness Analysis | Infectious Diseases | Social Determinants | Global -
ReviewPublication 2018Incorporating MCDA into HTA: A Focus on Lower Income Settings
The authors present key challenges, both methodological and practical against using multicriteria decision analysis (MCDA) …
The authors present key challenges, both methodological and practical against using multicriteria decision analysis (MCDA) in health technology assessment (HTA) as well as solutions to these challenges. They showcase lessons learned from previous applications of MCDS to HTA, including design, criteria of models, approaches for estimating costs and challenges with various approaches. By showing efforts that have succeeded in overcoming these challenges in lower and middle income-countries, they show how MCDA has the potential to…
Priority Setting/Ethics | Health/Medicine | Health Systems | Global -
ReviewPublication 2018Reflective Multicriteria for Healthcare Decision-Making? The EVIDEM Journey
The authors discuss a framework for mulicriteria decision making for healthcare decision making that was …
The authors discuss a framework for mulicriteria decision making for healthcare decision making that was created and used by the EVIDEM Collaboration between 2006 and 2017. This framework originally incorporated healthcare ethics, evidenced-based medicine, health economics, health technology assessment and multicriteria approaches to decision making. The authors present this modified 10th edition framework, which builds on these by enhancing the following 4 areas: universal healthcare, values and ethics, evidence-based interventions, and process transformation. The framework…
Priority Setting/Ethics | Health/Medicine | Health Systems | Global -
ReportPublication 2013Decision and Simulation Modeling Alongside Systematic Reviews
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks …
This chapter is part of a report entitled, Decision and Simulation Modeling in Systematic Reviews, that seeks to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The chapter discusses the role of decision analysis and decision-analytic models in health care, specifically within the context of the current emphasis on evidence-based medicine and the proliferation of systematic reviews. It describes the types of model available…
Evidence Synthesis | Health/Medicine | State-Transition | Dynamic Transmission | Microsimulation | Dynamic Simulation | Health Systems | Clinical Care -
ReviewPublication 2018Patient Variability Seldom Assessed in Cost-Effectiveness Studies
This article in Medical Decision Making reviews 200 articles published in 2014 to determine whether …
This article in Medical Decision Making reviews 200 articles published in 2014 to determine whether each cost-effectiveness analysis (CEA) study reported subgroup results and collected data on the defining characteristics of these subgroups. Since estimates can vary across patient subgroups when characteristics are influenced by preferences, outcome risks, treatment effectiveness, life expectancy, or associated costs it can be important to track and report these differences. The authors identified whether any of the CEA subgroup results…
Preferences/Values | Health/Medicine | Cost-Effectiveness Analysis | Social Determinants | Health Systems | Policy/Regulation | Global -
ReportPublication 2017Investing Early: Taking Stock of Outcomes and Economic Returns from Early Childhood Programs
The past two decades have been characterized by a growing body of research from diverse …
The past two decades have been characterized by a growing body of research from diverse disciplines - child development, psychology, neuroscience, and economics, among others - demonstrating the importance of establishing a strong foundation in the early years of life. The research evidence has served to document the range of early childhood services that can successfully put children and families on the path toward lifelong health and well-being, especially those at greatest risk of poor…
Evidence Synthesis | Health/Medicine | Benefit-Cost Analysis | Child/Nutrition | Social Determinants | Policy/Regulation | Education/Labor